Search Results - "Frankson, Rochelle"

Therapeutic Targeting of Oncogenic Tyrosine Phosphatases by Frankson, Rochelle, Yu, Zhi-Hong, Bai, Yunpeng, Li, Qinglin, Zhang, Ruo-Yu, Zhang, Zhong-Yin

“…Protein tyrosine phosphatases (PTP) are exciting and novel targets for cancer drug discovery that work in concert with protein tyrosine kinases (PTK) in…”
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Structure of ‘linkerless’ hydroxamic acid inhibitor-HDAC8 complex confirms the formation of an isoform-specific subpocket by Tabackman, Alexa A., Frankson, Rochelle, Marsan, Eric S., Perry, Kay, Cole, Kathryn E.

“…Histone deacetylases (HDACs) catalyze the hydrolysis of acetylated lysine side chains in histone and non-histone proteins, and play a critical role in the…”
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Structure of ‘linkerless’ hydroxamic acid inhibitor-HDAC8 complex confirms the formation of an isoform-specific subpocket by Tabackman, Alexa A., Frankson, Rochelle, Marsan, Eric S., Perry, Kay, Cole, Kathryn E.

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GroEL/ES inhibitors as potential antibiotics by Abdeen, Sanofar, Salim, Nilshad, Mammadova, Najiba, Summers, Corey M., Frankson, Rochelle, Ambrose, Andrew J., Anderson, Gregory G., Schultz, Peter G., Horwich, Arthur L., Chapman, Eli, Johnson, Steven M.

“…[Display omitted] We recently reported results from a high-throughput screening effort that identified 235 inhibitors of the Escherichia coli GroEL/ES…”
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