Search Results - "Franks, M."

Recurrent cortical circuits implement concentration-invariant odor coding by Bolding, Kevin A, Franks, Kevin M

“…Animals rely on olfaction to find food, attract mates, and avoid predators. To support these behaviors, they must be able to identify odors across different…”
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The Control of mRNA Decapping and P-Body Formation by Franks, Tobias M., Lykke-Andersen, Jens

“…mRNA decapping is a critical step in eukaryotic cytoplasmic mRNA turnover. Cytoplasmic mRNA decapping is catalyzed by Dcp2 in conjunction with its coactivator…”
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Conflict translates environmental and social risk into business costs by Franks, Daniel M., Davis, Rachel, Bebbington, Anthony J., Ali, Saleem H., Kemp, Deanna, Scurrah, Martin

“…Sustainability science has grown as a field of inquiry, but has said little about the role of large-scale private sector actors in socio-ecological systems…”
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Complementary codes for odor identity and intensity in olfactory cortex by Bolding, Kevin A, Franks, Kevin M

“…The ability to represent both stimulus identity and intensity is fundamental for perception. Using large-scale population recordings in awake mice, we find…”
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Embryo-scale, single-cell spatial transcriptomics by Srivatsan, Sanjay R, Regier, Mary C, Barkan, Eliza, Franks, Jennifer M, Packer, Jonathan S, Grosjean, Parker, Duran, Madeleine, Saxton, Sarah, Ladd, Jon J, Spielmann, Malte, Lois, Carlos, Lampe, Paul D, Shendure, Jay, Stevens, Kelly R, Trapnell, Cole

“…Spatial patterns of gene expression manifest at scales ranging from local (e.g., cell-cell interactions) to global (e.g., body axis patterning). However,…”
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Reversible, Specific, Active Aggregates of Endogenous Proteins Assemble upon Heat Stress by Wallace, Edward W.J., Kear-Scott, Jamie L., Pilipenko, Evgeny V., Schwartz, Michael H., Laskowski, Pawel R., Rojek, Alexandra E., Katanski, Christopher D., Riback, Joshua A., Dion, Michael F., Franks, Alexander M., Airoldi, Edoardo M., Pan, Tao, Budnik, Bogdan A., Drummond, D. Allan

“…Heat causes protein misfolding and aggregation and, in eukaryotic cells, triggers aggregation of proteins and RNA into stress granules. We have carried out…”
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Mineral security essential to achieving the Sustainable Development Goals by Franks, Daniel M., Keenan, Julia, Hailu, Degol

“…Minerals are essential ingredients of the Sustainable Development Goals, but in contrast to other natural resources, they are missing from the goals and…”
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Nup98 recruits the Wdr82-Set1A/COMPASS complex to promoters to regulate H3K4 trimethylation in hematopoietic progenitor cells by Franks, Tobias M, McCloskey, Asako, Shokirev, Maxim, Benner, Chris, Rathore, Annie, Hetzer, Martin W

“…Recent studies have shown that a subset of nucleoporins (Nups) can detach from the nuclear pore complex and move into the nuclear interior to regulate…”
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Tailings facility disclosures reveal stability risks by Franks, Daniel M., Stringer, Martin, Torres-Cruz, Luis A., Baker, Elaine, Valenta, Rick, Thygesen, Kristina, Matthews, Adam, Howchin, John, Barrie, Stephen

“…Tailings facility failures represent a significant risk to the environment and communities globally, but until now little data was available on the global…”
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Recurrent Circuitry Dynamically Shapes the Activation of Piriform Cortex by Franks, Kevin M., Russo, Marco J., Sosulski, Dara L., Mulligan, Abigail A., Siegelbaum, Steven A., Axel, Richard

“…In the piriform cortex, individual odorants activate a unique ensemble of neurons that are distributed without discernable spatial order. Piriform neurons…”
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Hyperphosphorylation amplifies UPF1 activity to resolve stalls in nonsense-mediated mRNA decay by Durand, Sébastien, Franks, Tobias M., Lykke-Andersen, Jens

“…Many gene expression factors contain repetitive phosphorylation sites for single kinases, but the functional significance is poorly understood. Here we present…”
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Th17 lymphocytes drive vascular and neuronal deficits in a mouse model of postinfectious autoimmune encephalitis by Platt, Maryann P., Bolding, Kevin A., Wayne, Charlotte R., Chaudhry, Sarah, Cutforth, Tyler, Franks, Kevin M., Agalliu, Dritan

“…Antibodies against neuronal receptors and synaptic proteins are associated with a group of ill-defined central nervous system (CNS) autoimmune diseases termed…”
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Initial recommendations for performing, benchmarking and reporting single-cell proteomics experiments by Gatto, Laurent, Aebersold, Ruedi, Cox, Juergen, Demichev, Vadim, Derks, Jason, Emmott, Edward, Franks, Alexander M., Ivanov, Alexander R., Kelly, Ryan T., Khoury, Luke, Leduc, Andrew, MacCoss, Michael J., Nemes, Peter, Perlman, David H., Petelski, Aleksandra A., Rose, Christopher M., Schoof, Erwin M., Van Eyk, Jennifer, Vanderaa, Christophe, Yates, John R., Slavov, Nikolai

“…Analyzing proteins from single cells by tandem mass spectrometry (MS) has recently become technically feasible. While such analysis has the potential to…”
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BioMethyl: an R package for biological interpretation of DNA methylation data by Wang, Yue, Franks, Jennifer M, Whitfield, Michael L, Cheng, Chao

“…Abstract Motivation The accumulation of publicly available DNA methylation datasets has resulted in the need for tools to interpret the specific cellular…”
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Parallel processing by distinct classes of principal neurons in the olfactory cortex by Nagappan, Shivathmihai, Franks, Kevin M

“…Understanding how distinct neuron types in a neural circuit process and propagate information is essential for understanding what the circuit does and how it…”
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Odor identity coding by distributed ensembles of neurons in the mouse olfactory cortex by Roland, Benjamin, Deneux, Thomas, Franks, Kevin M, Bathellier, Brice, Fleischmann, Alexander

“…Olfactory perception and behaviors critically depend on the ability to identify an odor across a wide range of concentrations. Here, we use calcium imaging to…”
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Global skin gene expression analysis of early diffuse cutaneous systemic sclerosis shows a prominent innate and adaptive inflammatory profile by Skaug, Brian, Khanna, Dinesh, Swindell, William R, Hinchcliff, Monique E, Frech, Tracy M, Steen, Virginia D, Hant, Faye N, Gordon, Jessica K, Shah, Ami A, Zhu, Lisha, Zheng, W Jim, Browning, Jeffrey L, Barron, Alexander M S, Wu, Minghua, Visvanathan, Sudha, Baum, Patrick, Franks, Jennifer M, Whitfield, Michael L, Shanmugam, Victoria K, Domsic, Robyn T, Castelino, Flavia V, Bernstein, Elana J, Wareing, Nancy, Lyons, Marka A, Ying, Jun, Charles, Julio, Mayes, Maureen D, Assassi, Shervin

“…Determine global skin transcriptome patterns of early diffuse systemic sclerosis (SSc) and how they differ from later disease. Skin biopsy RNA from 48 patients…”
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Preparation for voluntary movement in healthy and clinical populations: Evidence from startle by Carlsen, Anthony N, Maslovat, Dana, Franks, Ian M

“…Highlights ► Presenting a startling acoustic stimulus (SAS) during simple RT tasks results in substantial RT facilitation suggesting a subcortical mechanism…”
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Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction by Lam, Hilaire C, Cloonan, Suzanne M, Bhashyam, Abhiram R, Haspel, Jeffery A, Singh, Anju, Sathirapongsasuti, J Fah, Cervo, Morgan, Yao, Hongwei, Chung, Anna L, Mizumura, Kenji, An, Chang Hyeok, Shan, Bin, Franks, Jonathan M, Haley, Kathleen J, Owen, Caroline A, Tesfaigzi, Yohannes, Washko, George R, Quackenbush, John, Silverman, Edwin K, Rahman, Irfan, Kim, Hong Pyo, Mahmood, Ashfaq, Biswal, Shyam S, Ryter, Stefan W, Choi, Augustine M K

“…Chronic obstructive pulmonary disease (COPD) involves aberrant airway inflammatory responses to cigarette smoke (CS) that are associated with epithelial cell…”
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Recurrent circuitry is required to stabilize piriform cortex odor representations across brain states by Bolding, Kevin A, Nagappan, Shivathmihai, Han, Bao-Xia, Wang, Fan, Franks, Kevin M

“…Pattern completion, or the ability to retrieve stable neural activity patterns from noisy or partial cues, is a fundamental feature of memory. Theoretical…”
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