Search Results - "Franklyn, Kate"
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Definition and initial validation of a Lupus Low Disease Activity State (LLDAS)
Published in Annals of the rheumatic diseases (01-09-2016)“…Treating to low disease activity is routine in rheumatoid arthritis, but no comparable goal has been defined for systemic lupus erythematosus (SLE). We sought…”
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The need to define treatment goals for systemic lupus erythematosus
Published in Nature reviews. Rheumatology (01-09-2014)“…Active systemic lupus erythematosus (SLE) can manifest in heterogeneous clinical forms, making description of SLE clinical states difficult in patients with…”
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Association of the lupus low disease activity state (LLDAS) with health-related quality of life in a multinational prospective study
Published in Arthritis research & therapy (20-03-2017)“…Systemic lupus erythematosus (SLE) is associated with significant impairment of health-related quality of life (HR-QoL). Recently, meeting a definition of a…”
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Frequency and predictors of the lupus low disease activity state in a multi-national and multi-ethnic cohort
Published in Arthritis research & therapy (09-11-2016)“…Systemic lupus erythematosus (SLE) is a chronic heterogeneous disease with considerable burden from disease activity and damage. A novel clinical treatment…”
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Does expert opinion match the operational definition of the lupus low disease activity state (LLDAS)? A case based construct validity study
Published in Seminars in arthritis and rheumatism (01-06-2017)“…Abstract Objective To evaluate the construct validity of the Lupus Low Disease Activity State (LLDAS), a treatment target in systemic lupus erythematosus…”
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Comparative Effectiveness of Adalimumab vs Tofacitinib in Patients With Rheumatoid Arthritis in Australia
Published in JAMA network open (01-06-2023)“…There is a need for observational studies to supplement evidence from clinical trials, and the target trial emulation (TTE) framework can help avoid biases…”
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