Search Results - "Franken, P"
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1
The plant strengthening root endophyte Piriformospora indica: potential application and the biology behind
Published in Applied microbiology and biotechnology (01-12-2012)“…The successful conversion of plant production systems from conventional resource-exhausting to sustainable strategies depends on knowledge-based management of…”
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2
Circadian clock genes and sleep homeostasis
Published in The European journal of neuroscience (01-05-2009)“…Circadian and sleep‐homeostatic processes both contribute to sleep timing and sleep structure. Elimination of circadian rhythms through lesions of the…”
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3
The alfa and beta of tumours: a review of parameters of the linear-quadratic model, derived from clinical radiotherapy studies
Published in Radiation oncology (London, England) (16-05-2018)“…Prediction of radiobiological response is a major challenge in radiotherapy. Of several radiobiological models, the linear-quadratic (LQ) model has been best…”
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4
Effects of hyperthermia on DNA repair pathways: one treatment to inhibit them all
Published in Radiation oncology (London, England) (07-08-2015)“…The currently available arsenal of anticancer modalities includes many DNA damaging agents that can kill malignant cells. However, efficient DNA repair…”
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5
Principal cells of the brainstem's interaural sound level detector are temporal differentiators rather than integrators
Published in eLife (14-06-2018)“…The brainstem's lateral superior olive (LSO) is thought to be crucial for localizing high-frequency sounds by coding interaural sound level differences (ILD)…”
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6
Columnar processing of border ownership in primate visual cortex
Published in eLife (30-11-2021)“…To understand a visual scene, the brain segregates figures from background by assigning borders to foreground objects. Neurons in primate visual cortex encode…”
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7
Language Functions in Preterm-Born Children: A Systematic Review and Meta-analysis
Published in Pediatrics (Evanston) (01-04-2012)“…Preterm-born children (<37 weeks' gestation) have higher rates of language function problems compared with term-born children. It is unknown whether these…”
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8
Synaptic dysfunction, memory deficits and hippocampal atrophy due to ablation of mitochondrial fission in adult forebrain neurons
Published in Cell death and differentiation (01-01-2016)“…Well-balanced mitochondrial fission and fusion processes are essential for nervous system development. Loss of function of the main mitochondrial fission…”
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9
Hyperthermia: The Optimal Treatment to Overcome Radiation Resistant Hypoxia
Published in Cancers (09-01-2019)“…Regions of low oxygenation (hypoxia) are a characteristic feature of solid tumors, and cells existing in these regions are a major factor influencing radiation…”
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10
Mild hyperthermia inhibits homologous recombination, induces BRCA2 degradation, and sensitizes cancer cells to poly (ADP-ribose) polymerase-1 inhibition
Published in Proceedings of the National Academy of Sciences - PNAS (14-06-2011)“…Defective homologous recombination (HR) DNA repair imposed by BRCA1 or BRCA2 deficiency sensitizes cells to poly (ADP-ribose) polymerase (PARP)-1 inhibition…”
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11
Phosphate utilization by the fungal root endophyte Piriformospora indica
Published in Plant and soil (01-08-2016)“…Background and aim The root endophytic fungus Piriformospora indica increases plant resistance and tolerance to stress and promotes plant growth, but its…”
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12
Language outcome related to brain structures in school-aged preterm children: A systematic review
Published in PloS one (04-06-2018)“…Preterm children often have language problems. This atypical language development is probably due to atypical brain development. We conducted a systematic…”
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13
Spike-phase coupling patterns reveal laminar identity in primate cortex
Published in eLife (17-04-2023)“…The cortical column is one of the fundamental computational circuits in the brain. In order to understand the role neurons in different layers of this circuit…”
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14
Variation in Clinical Application of Hyperthermic Intraperitoneal Chemotherapy: A Review
Published in Cancers (11-01-2019)“…Peritoneal metastasis (PM) originating from gastrointestinal and gynecological malignancies are associated with a poor prognosis and rapid disease progression…”
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15
Glycinergic axonal inhibition subserves acute spatial sensitivity to sudden increases in sound intensity
Published in eLife (14-06-2021)“…Locomotion generates adventitious sounds which enable detection and localization of predators and prey. Such sounds contain brisk changes or transients in…”
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16
Tumour–stroma interactions in colorectal cancer: converging on β-catenin activation and cancer stemness
Published in British journal of cancer (17-06-2008)“…Sporadic cases of colorectal cancer are primarily initiated by gene mutations in members of the canonical Wnt pathway, ultimately resulting in β -catenin…”
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17
Single blind randomized phase III trial to investigate the benefit of a focal lesion ablative microboost in prostate cancer (FLAME-trial): study protocol for a randomized controlled trial
Published in Current controlled trials in cardiovascular medicine (05-12-2011)“…The treatment results of external beam radiotherapy for intermediate and high risk prostate cancer patients are insufficient with five-year biochemical relapse…”
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18
The systemic control of circadian gene expression
Published in Diabetes, obesity & metabolism (01-09-2015)“…The mammalian circadian timing system consists of a central pacemaker in the brain's suprachiasmatic nucleus (SCN) and subsidiary oscillators in nearly all…”
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19
Radiovirotherapy: principles and prospects in oncology
Published in Current pharmaceutical design (2012)“…Radiovirotherapy is defined as the use of viruses to deliver radioisotopic treatment into infected cells. Oncolytic viruses are able to selectively target and…”
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20
Chromatin mobility is increased at sites of DNA double-strand breaks
Published in Journal of cell science (01-05-2012)“…DNA double-strand breaks (DSBs) can efficiently kill cancer cells, but they can also produce unwanted chromosome rearrangements when DNA ends from different…”
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