Search Results - "Franke, Aaron S."

Fluorescence Linked Enzyme Chemoproteomic Strategy for Discovery of a Potent and Selective DAPK1 and ZIPK Inhibitor by Carlson, David A, Franke, Aaron S, Weitzel, Douglas H, Speer, Brittany L, Hughes, Philip F, Hagerty, Laura, Fortner, Christopher N, Veal, James M, Barta, Thomas E, Zieba, Bartosz J, Somlyo, Avril V, Sutherland, Cindy, Deng, Jing Ti, Walsh, Michael P, MacDonald, Justin A, Haystead, Timothy A. J

“…DAPK1 and ZIPK (also called DAPK3) are closely related serine/threonine protein kinases that regulate programmed cell death and phosphorylation of non-muscle…”
Get full text

Smooth and Cardiac Muscle-selective Knock-out of Krüppel-like Factor 4 Causes Postnatal Death and Growth Retardation by Yoshida, Tadashi, Gan, Qiong, Franke, Aaron S., Ho, Ruoya, Zhang, Jifeng, Chen, Y. Eugene, Hayashi, Matsuhiko, Majesky, Mark W., Somlyo, Avril V., Owens, Gary K.

“…Krüppel-like factor 4 (Klf4) is a transcription factor involved in differentiation and proliferation in multiple tissues. We demonstrated previously that…”
Get full text

The cAMP-responsive Rap1 Guanine Nucleotide Exchange Factor, Epac, Induces Smooth Muscle Relaxation by Down-regulation of RhoA Activity by Zieba, Bartosz J., Artamonov, Mykhaylo V., Jin, Li, Momotani, Ko, Ho, Ruoya, Franke, Aaron S., Neppl, Ronald L., Stevenson, Andra S., Khromov, Alexander S., Chrzanowska-Wodnicka, Magdalena, Somlyo, Avril V.

“…Agonist activation of the small GTPase, RhoA, and its effector Rho kinase leads to down-regulation of smooth muscle (SM) myosin light chain phosphatase…”
Get full text

Signaling Pathways That Control Rho Kinase Activity Maintain the Embryonic Epicardial Progenitor State by Artamonov, Mykhaylo V., Jin, Li, Franke, Aaron S., Momotani, Ko, Ho, Ruoya, Dong, Xiu Rong, Majesky, Mark W., Somlyo, Avril V.

“…This study identifies signaling pathways that play key roles in the formation and maintenance of epicardial cells, a source of progenitors for coronary smooth…”
Get full text

Myosin Cross-Bridge Kinetics and the Mechanism of Catch by Franke, Aaron S., Mooers, Susan U., Narayan, Srinivasa R., Siegman, Marion J., Butler, Thomas M.

“…Catch force in molluscan smooth muscle requires little, if any, energy input and is controlled by the phosphorylation state of the thick filament-associated…”
Get full text

The cAMP responsive Rap1 guanine nucleotide exchange factor, Epac, induces smooth muscle relaxation by down regulation of RhoA activity by Zieba, Bartosz Jakub, Artamonov, Mykhaylo V, Jin, Li, Momotani, Ko, Ho, Ruoya, Franke, Aaron S, Neppl, Ronald L, Stevenson, Andra S, Khromov, Alexander S, Chrzanowska‐Wodnicka, Magdalena, Somlyo, Avril V

“…This study reports a new mechanism of cAMP mediated relaxation of Ca2+sensitized force, in smooth muscle (SM) through Epac, a GTP exchange factor for the small…”
Get full text

Myosin crossbridge kinetics and the mechanism of catch: Single turnover of myosin-bound ADP in catch muscle by Franke, Aaron S

Get full text