Search Results - "Frank de Araújo, Eliseu"

Tolerogenic Plasmacytoid Dendritic Cells Control Paracoccidioides brasiliensis Infection by Inducting Regulatory T Cells in an IDO-Dependent Manner by Araújo, Eliseu Frank de, Medeiros, Daniella Helena, Galdino, Nayane Alves de Lima, Condino-Neto, Antônio, Calich, Vera Lúcia Garcia, Loures, Flávio Vieira

“…Plasmacytoid dendritic cells (pDCs), considered critical for immunity against viruses, were recently associated with defense mechanisms against fungal…”
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Mannosyl-recognizing receptors induce an M1-like phenotype in macrophages of susceptible mice but an M2-like phenotype in mice resistant to a fungal infection by Feriotti, Claudia, Loures, Flávio V, Frank de Araújo, Eliseu, da Costa, Tania Alves, Calich, Vera L G

“…In addition to alpha1,3 glucan, mannan and mannan-linked proteins are expressed in the outer layer of Paracoccidioides brasiliensis yeasts. The recognition of…”
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Pulmonary paracoccidioidomycosis in AhR deficient hosts is severe and associated with defective Treg and Th22 responses by de Araújo, Eliseu Frank, Preite, Nycolas Willian, Veldhoen, Marc, Loures, Flávio Vieira, Calich, Vera Lúcia Garcia

“…© The Author(s) 2020. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing,…”
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TNF-α and CD8+ T cells mediate the beneficial effects of nitric oxide synthase-2 deficiency in pulmonary paracoccidioidomycosis by Bernardino, Simone, Pina, Adriana, Felonato, Maíra, Costa, Tânia A, Frank de Araújo, Eliseu, Feriotti, Cláudia, Bazan, Silvia Boschi, Keller, Alexandre C, Leite, Katia R M, Calich, Vera L G

“…Nitric oxide (NO), a key antimicrobial molecule, was previously shown to exert a dual role in paracoccidioidomycosis, an endemic fungal infection in Latin…”
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The IDO-AhR Axis Controls Th17/Treg Immunity in a Pulmonary Model of Fungal Infection by de Araújo, Eliseu Frank, Feriotti, Claudia, Galdino, Nayane Alves de Lima, Preite, Nycolas Willian, Calich, Vera Lúcia Garcia, Loures, Flávio Vieira

“…In infectious diseases, the enzyme indoleamine 2,3 dioxygenase-1 (IDO1) that catalyzes the tryptophan (Trp) degradation along the kynurenines (Kyn) pathway has…”
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NOD-Like Receptor P3 Inflammasome Controls Protective Th1/Th17 Immunity against Pulmonary Paracoccidioidomycosis by Feriotti, Claudia, de Araújo, Eliseu Frank, Loures, Flavio Vieira, da Costa, Tania Alves, Galdino, Nayane Alves de Lima, Zamboni, Dario Simões, Calich, Vera Lucia Garcia

“…The NOD-like receptor P3 (NLRP3) inflammasome is an intracellular multimeric complex that triggers the activation of inflammatory caspases and the maturation…”
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Loss- and Gain-of-Function Approaches Indicate a Dual Role Exerted by Regulatory T Cells in Pulmonary Paracoccidioidomycosis by Bazan, Silvia B, Costa, Tania A, de Araújo, Eliseu Frank, Feriotti, Claudia, Loures, Flávio V, Pretel, Fernando D, Calich, Vera L G

“…Paracoccidioidomycosis (PCM), is a pulmonary fungal disease whose severity depends on the adequate development of T cell immunity. Although regulatory T (Treg)…”
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Disease Tolerance Mediated by Phosphorylated Indoleamine-2,3 Dioxygenase Confers Resistance to a Primary Fungal Pathogen by de Araújo, Eliseu Frank, Loures, Flávio Vieira, Feriotti, Cláudia, Costa, Tania, Vacca, Carmine, Puccetti, Paolo, Romani, Luigina, Calich, Vera Lúcia Garcia

“…Resistance to primary fungal pathogens is usually attributed to the proinflammatory mechanisms of immunity conferred by interferon-γ activation of phagocytes…”
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Anti-CD25 treatment depletes Treg cells and decreases disease severity in susceptible and resistant mice infected with Paracoccidioides brasiliensis by Felonato, Maíra, Pina, Adriana, de Araujo, Eliseu Frank, Loures, Flávio V, Bazan, Silvia B, Feriotti, Cláudia, Calich, Vera L G

“…Regulatory T (Treg) cells are fundamental in the control of immunity and excessive tissue pathology. In paracoccidioidomycosis, an endemic mycosis of Latin…”
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Myeloid Dendritic Cells (DCs) of Mice Susceptible to Paracoccidioidomycosis Suppress T Cell Responses whereas Myeloid and Plasmacytoid DCs from Resistant Mice Induce Effector and Regulatory T Cells by Pina, Adriana, de Araujo, Eliseu Frank, Felonato, Maíra, Loures, Flávio V, Feriotti, Claudia, Bernardino, Simone, Barbuto, José Alexandre M, Calich, Vera L G

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CD28 Exerts Protective and Detrimental Effects in a Pulmonary Model of Paracoccidioidomycosis by Felonato, Maíra, Pina, Adriana, Bernardino, Simone, Loures, Flávio V, de Araujo, Eliseu Frank, Calich, Vera L.G

“…T-cell immunity has been claimed as the main immunoprotective mechanism against Paracoccidioides brasiliensis infection, the most important fungal infection in…”
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CpG-ODN Shapes Alum Adjuvant Activity Signaling via MyD88 and IL-10 by Mirotti, Luciana, Alberca Custódio, Ricardo Wesley, Gomes, Eliane, Rammauro, Florencia, de Araujo, Eliseu Frank, Garcia Calich, Vera Lucia, Russo, Momtchilo

“…Aluminum-containing adjuvants usually referred as Alum are considered as T helper type-2 (Th2) adjuvants, while agonists of toll-like receptors (TLRs) are…”
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Tnf-α and [CD8.sup.+] T cells mediate the beneficial effects of nitric oxide synthase-2 deficiency in pulmonary paracoccidioidomycosis by Bernardino, Simone, Pina, Adriana, Felonato, Maira, Costa, Tania A, de Araujo, Eliseu Frank, Feriotti, Claudia, Bazan, Silvia Boschi, Keller, Alexandre C, Leite, Katia R.M, Calich, Vera L.G

“…Background: Nitric oxide (NO), a key antimicrobial molecule, was previously shown to exert a dual role in paracoccidioidomycosis, an endemic fungal infection…”
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