Search Results - "Frank, V."
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Crystal Structure of the Ribosome Bound to EF-Tu and Aminoacyl-tRNA
Published in Science (American Association for the Advancement of Science) (30-10-2009)“…The ribosome selects a correct transfer RNA (tRNA) for each amino acid added to the polypeptide chain, as directed by messenger RNA. Aminoacyl-tRNA is…”
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2
Structure of the 70S Ribosome Complexed with mRNA and tRNA
Published in Science (American Association for the Advancement of Science) (29-09-2006)“…The crystal structure of the bacterial 70S ribosome refined to 2.8 angstrom resolution reveals atomic details of its interactions with messenger RNA (mRNA) and…”
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3
Expanded use of sense codons is regulated by modified cytidines in tRNA
Published in Proceedings of the National Academy of Sciences - PNAS (02-07-2013)“…Codon use among the three domains of life is not confined to the universal genetic code. With only 22 tRNA genes in mammalian mitochondria, exceptions from the…”
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Cell culture media for recombinant protein expression in Chinese hamster ovary (CHO) cells: History, key components, and optimization strategies
Published in Biotechnology progress (01-11-2018)“…The culture of Chinese Hamster Ovary (CHO) cells for modern industrial applications, such as expression of recombinant proteins, requires media that support…”
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Mechanism for expanding the decoding capacity of transfer RNAs by modification of uridines
Published in Nature structural & molecular biology (01-06-2007)“…One of the most prevalent base modifications involved in decoding is uridine 5-oxyacetic acid at the wobble position of tRNA. It has been known for several…”
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6
GTPase activation of elongation factor EF-Tu by the ribosome during decoding
Published in The EMBO journal (18-03-2009)“…We have used single‐particle reconstruction in cryo‐electron microscopy to determine a structure of the Thermus thermophilus ribosome in which the ternary…”
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Ecofriendly Antifouling Marine Coatings
Published in ACS sustainable chemistry & engineering (06-04-2015)“…Foul release coatings were first used on vessels in the early 1990s, but despite early excitement about the technology, they have had a prolonged modest market…”
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8
Energy relaxation in a vacuum capacitor-resistor circuit: measurement of multiple decays with divergent time constants
Published in AIP advances (01-03-2024)“…The decay of the electrical energy in a resistor-vacuum capacitor circuit is shown to involve multiple relaxation processes, with dramatically different time…”
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HFpEF, a Disease of the Vasculature: A Closer Look at the Other Half
Published in Mayo Clinic proceedings (01-09-2018)“…Patients with heart failure are commonly divided into those with reduced ejection fraction (EF<40%) and those with preserved ejection fraction (HFpEF; EF>50%)…”
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10
Aqueous Self-Assembly of Giant Bottlebrush Block Copolymer Surfactants as Shape-Tunable Building Blocks
Published in Journal of the American Chemical Society (28-05-2014)“…Programmed self-assembly of well-defined molecular building blocks enables the fabrication of precisely structured nanomaterials. In this work, we explore a…”
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11
Environmentally Benign Sol–Gel Antifouling and Foul-Releasing Coatings
Published in Accounts of chemical research (18-02-2014)“…Biofouling on ships and boats, characterized by aquatic bacteria and small organisms attaching to the hull, is an important global issue, since over 80000 tons…”
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12
The central role of protein S12 in organizing the structure of the decoding site of the ribosome
Published in RNA (Cambridge) (01-12-2013)“…The ribosome decodes mRNA by monitoring the geometry of codon-anticodon base-pairing using a set of universally conserved 16S rRNA nucleotides within the…”
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13
An Introduction to Primary Care and Psychology
Published in The American psychologist (01-05-2014)“…The health care system in the United States has been less effective and more expensive than it needs to be, but the organizational and political will to…”
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14
Bayesian Adaptive Randomization Trial of Passive Scattering Proton Therapy and Intensity-Modulated Photon Radiotherapy for Locally Advanced Non-Small-Cell Lung Cancer
Published in Journal of clinical oncology (20-06-2018)“…Purpose This randomized trial compared outcomes of passive scattering proton therapy (PSPT) versus intensity-modulated (photon) radiotherapy (IMRT), both with…”
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A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine
Published in Journal of molecular biology (14-02-2020)“…Three of six arginine codons (CGU, CGC, and CGA) are decoded by two Escherichia coli tRNAArg isoacceptors. The anticodon stem and loop (ASL) domains of…”
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16
Collective Behavior in Quantum Interference: A Supplementary Superposition Principle
Published in Annalen der Physik (01-01-2023)“…An interferometer in which all of its components are treated as quantum bodies is examined with the standard interpretation and with a model in which its…”
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17
Response rates to single-agent chemotherapy after exposure to immune checkpoint inhibitors in advanced non-small cell lung cancer
Published in Lung cancer (Amsterdam, Netherlands) (01-10-2017)“…•In NSCLC, overall response rate to single-agent chemotherapy after anti-PD1 failure was 39%.•Eleven out of 28 patients achieved a response (8 confirmed, 3…”
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18
Shading and watering as a tool to mitigate the impacts of climate change in sea turtle nests
Published in PloS one (01-06-2015)“…Increasing sand temperatures resulting from climate change may negatively impact sea turtle nests by altering sex ratios and decreasing reproductive output. We…”
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Induction of Multiple Alternative Mitogenic Signaling Pathways Accompanies the Emergence of Drug-Tolerant Cancer Cells
Published in Cancers (29-02-2024)“…Drug resistance can evolve from a subpopulation of cancer cells that initially survive drug treatment and then gradually form a pool of drug-tolerant cells…”
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Reductive Side of Water Splitting in Artificial Photosynthesis: New Homogeneous Photosystems of Great Activity and Mechanistic Insight
Published in Journal of the American Chemical Society (10-11-2010)“…Rhodamine photosensitizers (PSs) substituting S or Se for O in the xanthene ring give turnover numbers (TONs) as high as 9000 for the generation of hydrogen…”
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