Search Results - "Frank, SJ"
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Technology Insight: PET and PET/CT in head and neck tumor staging and radiation therapy planning
Published in Nature clinical practice. Oncology (01-10-2005)“…The evolving utilization of functional imaging, mainly 2-[18F]fluoro-2-deoxyglucose (18FDG) imaging, with positron emission tomography (PET) and PET/CT, is…”
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Metalloproteinases and the modulation of GH signaling
Published in Journal of endocrinology (01-09-2002)“…The metzincin metalloproteinase, tumor necrosis factor-alpha-converting enzyme (TACE), also known as ADAM (a disintegrin and metalloproteinase) 17, has…”
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Structural mutations of the T cell receptor ζ chain and its role in T cell activation
Published in Science (American Association for the Advancement of Science) (13-07-1990)“…T cell hybridomas that express zeta zeta, but not zeta eta, dimers in their T cell receptors (TCRs) produce interleukin-2 (IL-2) and undergo an inhibition of…”
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PRELIMINARY DESIGN OF A PROTOTYPE OPTICALLY STIMULATED LUMINESCENT DOSIMETER READER FOR MATERIAL CHARACTERIZATION
Published in Health physics (1958) (01-07-2018)“…Optically stimulated luminescent (OSL) materials form the basis for dating techniques, while several OSL materials are commonly used for radiation dosimetry…”
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Definitive radiation therapy for squamous cell carcinoma of the vagina
Published in International journal of radiation oncology, biology, physics (01-05-2005)“…To evaluate outcome and describe clinical treatment guidelines for patients with primary squamous cell carcinoma of the vagina treated with definitive…”
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Dairy cows experience selective reduction of the hepatic growth hormone receptor during the periparturient period
Published in Journal of endocrinology (01-05-2004)“…At parturition, dairy cows experience a 70% reduction in plasma IGF-I. This reduction coincides with decreased abundance of GHR1A, the liver-specific…”
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Phase I study of vandetanib with radiation therapy with or without cisplatin in locally advanced head and neck squamous cell carcinoma
Published in Head & neck (01-03-2016)“…Background Vandetanib, added to cisplatin and radiation therapy (RT) overcomes chemoradiation therapy (CRT) and epidermal growth factor receptor (EGFR)…”
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Favorable patient reported outcomes following IMRT for early carcinomas of the tonsillar fossa: Results from a symptom assessment study
Published in Radiotherapy and oncology (01-10-2015)“…Abstract Background A questionnaire-based study was conducted to assess long-term patient reported outcomes (PROs) following definitive IMRT-based treatment…”
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Clinical outcomes and patterns of disease recurrence following intensity modulated proton therapy for oropharyngeal squamous carcinoma: results from a single institution prospective study
Published in International journal of radiation oncology, biology, physics (12-02-2016)Get full text
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Towards a Politics of Communion. By AnnaRowlands. London: T & T Clark, 2021. Pp. xvi, 315. £75.00 ( HB )/£25.99 ( PB )
Published in Heythrop journal (01-01-2023)Get full text
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Tumor necrosis factor-alpha converting enzyme (TACE) is a growth hormone binding protein (GHBP) sheddase: the metalloprotease TACE/ADAM-17 is critical for (PMA-induced) GH receptor proteolysis and GHBP generation
Published in Endocrinology (Philadelphia) (01-12-2000)“…The GH binding protein (GHBP), which exists in many vertebrates, is a circulating high affinity binding protein corresponding to the extracellular domain of…”
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TH‐C‐BRD‐09: Successes and Limitations of Online Range Adaptive Spot Scanning Proton Therapy for NSCLC
Published in Medical physics (Lancaster) (01-06-2014)“…Purpose: To determine the ability to adapt discrete spot‐scanning proton therapy (SSPT) plans based on geometric changes of anatomy to minimize normal tissue…”
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Caveolar and lipid raft localization of the growth hormone receptor and its signaling elements: impact on growth hormone signaling
Published in The Journal of biological chemistry (14-05-2004)“…The growth hormone receptor (GHR) is a cell surface receptor that mediates the somatogenic and metabolic effects of the growth hormone (GH). GHR signaling is…”
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Growth hormone-induced phosphorylation of epidermal growth factor (EGF) receptor in 3T3-F442A cells. Modulation of EGF-induced trafficking and signaling
Published in The Journal of biological chemistry (23-05-2003)“…Growth hormone (GH) promotes signaling by causing activation of the non-receptor tyrosine kinase, JAK2, which associates with the GH receptor. GH causes…”
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Constitutive α‐secretase cleavage of the β‐amyloid precursor protein in the furin‐deficient LoVo cell line: involvement of the pro‐hormone convertase 7 and the disintegrin metalloprotease ADAM10
Published in Journal of neurochemistry (01-03-2001)“…The β‐amyloid precursor protein (βAPP) undergoes a physiological cleavage triggered by one or several proteolytic activities referred to as α‐secretases,…”
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Insulin increases the abundance of the growth hormone receptor in liver and adipose tissue of periparturient dairy cows
Published in The Journal of nutrition (01-05-2004)“…After parturition, increased growth hormone (GH) secretion is important to preserve the metabolic homeostasis of energy-deficient dairy cows. Elevated plasma…”
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Growth Hormone Receptor Is a Target for Presenilin-dependent γ-Secretase Cleavage
Published in The Journal of biological chemistry (13-05-2005)“…Growth hormone receptor (GHR) is a cytokine receptor superfamily member that binds growth hormone (GH) via its extracellular domain and signals via interaction…”
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Growth hormone signalling and its regulation: Preventing too much of a good thing
Published in Growth Hormone & IGF Research (01-08-2001)“…Growth hormone (GH) is a major growth-promoting and metabolic regulatory hormone. Interaction of GH with its cell surface GH receptor (GHR), by virtue of…”
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