Search Results - "Frank, S. J."
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Serum amyloid P component (SAP) modulates antidepressant effects through promoting membrane insertion of the serotonin transporter
Published in Neuropsychopharmacology (New York, N.Y.) (01-02-2023)“…Serum amyloid P component (SAP) is a universal constituent of human amyloid deposits including those in Alzheimer's disease. SAP has been observed to be…”
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Delineation of Domains Within the Cannabinoid CB1 and Dopamine D2 Receptors That Mediate the Formation of the Heterodimer Complex
Published in Journal of molecular neuroscience (01-05-2014)“…Both the cannabinoid CB1 receptor (CB1) and dopamine D2 receptor (D2R) are G protein-coupled receptors that are linked to inhibitory Gαi/o protein, whereby…”
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A Physical Interaction between the Dopamine Transporter and DJ-1 Facilitates Increased Dopamine Reuptake
Published in PloS one (25-08-2015)“…The regulation of the dopamine transporter (DAT) impacts extracellular dopamine levels after release from dopaminergic neurons. Furthermore, a variety of…”
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Uncoupling the D1- N- Methyl-D-Aspartate (NMDA) Receptor Complex Promotes NMDA-Dependent Long-Term Potentiation and Working Memory
Published in Biological psychiatry (1969) (01-02-2010)“…Background Although dopamine D1 receptors are involved in working memory, how D1 receptors contribute to this process remains unclear. Numerous studies have…”
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NCS-1 in the Dentate Gyrus Promotes Exploration, Synaptic Plasticity, and Rapid Acquisition of Spatial Memory
Published in Neuron (Cambridge, Mass.) (10-09-2009)“…The molecular underpinnings of exploration and its link to learning and memory remain poorly understood. Here we show that inducible, modest overexpression of…”
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Endosomal recycling and dopamine neurotransmission: Exploring the links between the retromer and Parkinson's disease
Published in Synapse (New York, N.Y.) (01-03-2022)“…The retromer complex is an evolutionarily conserved protein complex involved in the endosomal recycling of various cargo proteins. It is ubiquitously expressed…”
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Dopamine transporter cell surface localization facilitated by a direct interaction with the dopamine D2 receptor
Published in The EMBO journal (18-04-2007)“…Altered synaptic dopamine levels have been implicated in several neurological/neuropsychiatric disorders, including drug addiction and schizophrenia. However,…”
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Regulation of Dopamine D1 Receptor Function by Physical Interaction with the NMDA Receptors
Published in The Journal of neuroscience (04-02-2004)“…Functional interactions between dopamine D1-like receptors and NMDA subtype glutamate receptors have been implicated in the maintenance of normal brain…”
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Neuroprotective effects of extracellular DJ‐1 on reperfusion injury in SH‐SY5Y cells
Published in Synapse (New York, N.Y.) (01-05-2017)“…Using an in vitro model of ischemic stroke we treated differentiated SH‐SY5Y cells to oxygen‐glucose deprivation (OGD) followed by a reperfusion period where…”
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10
Unified theory regarding A/P and M/L balance in quiet stance
Published in Journal of neurophysiology (01-06-1996)“…1. Control of posture in quiet stance has been quantified by center of pressure (COP) changes in the anterior-posterior (A/P) and medial-lateral (M/L)…”
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Compensatory postural adaptations during continuous, variable amplitude perturbations reveal generalized rather than sequence-specific learning
Published in Experimental brain research (01-06-2008)“…We examined changes in the motor organization of postural control in response to continuous, variable amplitude oscillations evoked by a translating platform…”
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12
Prolactin modulates phosphorylation, signaling and trafficking of epidermal growth factor receptor in human T47D breast cancer cells
Published in Oncogene (07-12-2006)“…Prolactin (PRL) is a polypeptide hormone produced by the anterior pituitary gland and other sites that acts both systemically and locally to cause lactation…”
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13
Influence of Postural Anxiety on Postural Reactions to Multi-Directional Surface Rotations
Published in Journal of neurophysiology (01-12-2004)“…1 Department of Kinesiology, University of Waterloo, Waterloo, Ontario N2L 3G1 Canada; 2 Department of Physical Education and Kinesiology, Brock University,…”
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Direct interaction between GluR2 and GAPDH regulates AMPAR-mediated excitotoxicity
Published in Molecular brain (26-04-2012)“…Over-activation of AMPARs (α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid subtype glutamate receptors) is implicated in excitotoxic neuronal death…”
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Centrally Initiated Postural Adjustments in Parkinsonian Patients On and Off Levodopa
Published in Journal of neurophysiology (01-11-2000)“… 1 Department of Kinesiology, University of Waterloo, Waterloo, Ontario N2L 3G1, Canada; 2 Neurological Sciences Institute, Oregon Health Sciences…”
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An evaluation of sensorimotor integration during locomotion toward a target in Parkinson’s disease
Published in Neuroscience (2005)“…Recent research suggests that basal ganglia dysfunction may result in problems integrating concurrent vision and proprioception during movement. We evaluated…”
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17
Effect of nutrition on the GH responsiveness of liver and adipose tissue in dairy cows
Published in Journal of endocrinology (01-10-2007)“…Dairy cows enter a period of energy insufficiency after parturition. In liver, this energy deficit leads to reduced expression of the liver-specific GH…”
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Addition of short-term androgen deprivation therapy to dose-escalated radiation therapy improves failure-free survival for select men with intermediate-risk prostate cancer
Published in Annals of oncology (01-09-2012)“…Dose-escalated (DE) radiation therapy (RT) and androgen deprivation therapy (ADT) improve prostate cancer outcomes over standard-dose RT. The benefit of adding…”
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Control of Dynamic Stability During Gait Termination on a Slippery Surface
Published in Journal of neurophysiology (01-01-2005)“…Gait and Posture Laboratory, Kinesiology Department, University of Waterloo, Waterloo, Ontario, Canada Submitted 26 April 2004; accepted in final form 22 July…”
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Protein-Protein Coupling/Uncoupling Enables Dopamine D2 Receptor Regulation of AMPA Receptor-Mediated Excitotoxicity
Published in The Journal of neuroscience (27-04-2005)“…here is considerable evidence that dopamine D2 receptors can modulate AMPA receptor-mediated neurotoxicity. However, the molecular mechanism underlying this…”
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