Search Results - "Frank, Konrad"
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MET amplification status in therapy-naïve adeno- and squamous cell carcinomas of the lung
Published in Clinical cancer research (15-02-2015)“…MET is a potential therapeutic target in lung cancer and both MET tyrosine kinase inhibitors and monoclonal antibodies have entered clinical trials. MET…”
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2
Sleep-disordered breathing in patients with cardiovascular diseases cannot be detected by ESS, STOP-BANG, and Berlin questionnaires
Published in Clinical research in cardiology (01-11-2018)“…Sleep-disordered breathing (SDB) is highly prevalent in patients with cardiovascular diseases (CVD) and associated with poor outcome. At least 50% of heart…”
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3
Only I Know Now, of Course, How to Deal With it, or Better to Deal With it: A Mixed Methods Phase II Study of a Cognitive and Behavioral Intervention for the Management of Episodic Breathlessness
Published in Journal of pain and symptom management (01-05-2022)“…Episodic breathlessness is characterized by increased breathlessness intensity, and it is burdensome for patients. A vicious cycle of…”
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4
Definition of a fluorescence in-situ hybridization score identifies high- and low-level FGFR1 amplification types in squamous cell lung cancer
Published in Modern pathology (01-11-2012)“…We recently reported fibroblast growth factor receptor-type 1 ( FGFR1 ) amplification to be associated with therapeutically tractable FGFR1 dependency in…”
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5
Risk-adapted robotic stereotactic body radiation therapy for inoperable early-stage non-small-cell lung cancer
Published in Strahlentherapie und Onkologie (01-02-2018)“…Purpose To evaluate efficacy and toxicity of stereotactic body radiation therapy (SBRT) with CyberKnife® (Accuray, Sunnyvale, CA, USA) in a selected cohort of…”
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6
Spectrum of Uveitis in A German Tertiary Center: Review of 474 Consecutive Patients
Published in Ocular immunology and inflammation (04-07-2015)“…Purpose: To analyze the spectrum of uveitis at a German tertiary center. Patients and methods: A total of 474 consecutive patients with uveitis were classified…”
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7
Interaction of panic and episodic breathlessness among patients with life-limiting diseases: a cross-sectional study
Published in Annals of palliative medicine (01-09-2023)Get full text
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8
Overcoming EGFRG724S-mediated osimertinib resistance through unique binding characteristics of second-generation EGFR inhibitors
Published in Nature communications (07-11-2018)“…The emergence of acquired resistance against targeted drugs remains a major clinical challenge in lung adenocarcinoma patients. In a subgroup of these patients…”
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9
Losartan prevents stretch-induced electrical remodeling in cultured atrial neonatal myocytes
Published in American journal of physiology. Heart and circulatory physiology (01-06-2007)“…Atrial fibrillation (AF) is the most frequent arrhythmia found in clinical practice. In recent studies, a decrease in the development or recurrence of AF was…”
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10
Chronic Phospholamban–Sarcoplasmic Reticulum Calcium ATPase Interaction Is the Critical Calcium Cycling Defect in Dilated Cardiomyopathy
Published in Cell (29-10-1999)“…Dilated cardiomyopathy and end-stage heart failure result in multiple defects in cardiac excitation–contraction coupling. Via complementation of a genetically…”
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11
Pneumomediastinum and Striking Family History: Uncommon Case of Birt-Hogg-Dubé Syndrome
Published in Internal Medicine (01-01-2012)“…Birt-Hogg-Dubé syndrome is a rare autosomal dominant condition caused by a germline mutation in the folliculin gene, which is characterized by skin…”
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12
Predictive value of serum markers for pulmonary involvement in ocular sarcoidosis
Published in Acta ophthalmologica (Oxford, England) (01-05-2014)Get full text
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13
Severe dyspnoea during late pregnancy in a woman with history of asthma
Published in Clinical research in cardiology (01-12-2011)Get full text
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14
Sarcoplasmic Ca2+ release is prolonged in nonfailing myocardium of diabetic patients
Published in Molecular and cellular biochemistry (01-01-2008)“…Background Asymptomatic diabetic patients have a high incidence of clinically unrecognized left ventricular dysfunction with an abnormal cardiac response to…”
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Evidence for functional relevance of an enhanced expression of the Na+-Ca2+ exchanger in failing human myocardium
Published in Circulation (New York, N.Y.) (01-09-1996)“…The present study aimed at investigating the expression of the Na(+)-Ca2+ exchanger and its functional role in human failing myocardium. Na(+)-Ca2+ exchanger…”
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16
Influence of cell treatment with PDGF-BB and reperfusion on cardiac persistence of mononuclear and mesenchymal bone marrow cells after transplantation into acute myocardial infarction in rats
Published in Cell transplantation (01-01-2009)“…Bone marrow cells are used for cell therapy after myocardial infarction (MI) with promising results. However, cardiac persistence of transplanted cells is…”
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17
Surfactant application in experimental lung transplantation
Published in The Journal of heart and lung transplantation (01-03-2013)“…Background Non–heart-beating donor (NHBD) utilization can significantly increase the limited donor lung pool. However, optimal preservation of organ function…”
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18
Overcoming EGFR G724S-mediated osimertinib resistance through unique binding characteristics of second-generation EGFR inhibitors
Published in Nature communications (01-11-2018)“…The emergence of acquired resistance against targeted drugs remains a major clinical challenge in lung adenocarcinoma patients. In a subgroup of these patients…”
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19
Diabetes-related defects in sarcoplasmic Ca²⁺ release are prevented by inactivation of Gα₁₁ and Gαq in murine cardiomyocytes
Published in Molecular and cellular biochemistry (2010)“…Neurohumoral stimulation of Gq-coupled receptors has been proposed as a central mechanism in the pathogenesis of diabetic heart disease. The resulting…”
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20
Angiostatin: drying out the roots in cardiac muscle
Published in Heart (British Cardiac Society) (01-02-2009)Get more information
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