Search Results - "Frank, Dmitry"
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The Development of Novel Drug Treatments for Stroke Patients: A Review
Published in International journal of molecular sciences (21-05-2022)“…Acute ischemic stroke is a critical condition that can result in disability and death. The consequences of this medical condition depend on various factors,…”
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Pathophysiology and Current Drug Treatments for Post-Stroke Depression: A Review
Published in International journal of molecular sciences (01-12-2022)“…Post-stroke depression (PSD) is a biopsychosocial disorder that affects individuals who have suffered a stroke at any point. PSD has a 20 to 60 percent…”
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3
Early life stress induces submissive behavior in adult rats
Published in Behavioural brain research (17-10-2019)“…Maternal-deprivation of rodent pups is a relevant model of extreme early-life stress that can be relevant to the understanding of long-term effects of war,…”
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4
The Integrity of the Blood-Brain Barrier as a Critical Factor for Regulating Glutamate Levels in Traumatic Brain Injury
Published in International journal of molecular sciences (01-03-2023)“…A healthy blood-brain barrier (BBB) shields the brain from high concentrations of blood glutamate, which can cause neurotoxicity and neurodegeneration. It is…”
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Establishing a 3-Tesla Magnetic Resonance Imaging Method for Assessing Diffuse Axonal Brain Injury in Rats
Published in International journal of molecular sciences (01-04-2024)“…Traumatic brain injury (TBI) significantly contributes to death and disability worldwide. However, treatment options remain limited. Here, we focus on a…”
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Traumatic brain injury-induced submissive behavior in rats: link to depression and anxiety
Published in Translational psychiatry (07-06-2022)“…Traumatic brain injury (TBI) affects millions of people worldwide, many of whom are affected with post-TBI mood disorders or behavioral changes, including…”
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A Novel Method for Assessing Cerebral Edema, Infarcted Zone and Blood-Brain Barrier Breakdown in a Single Post-stroke Rodent Brain
Published in Frontiers in neuroscience (16-10-2019)“…Stroke is a major cause of global morbidity and mortality. Middle cerebral artery occlusion (MCAO) has historically been the most common animal model of…”
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Blood glutamate scavenging as a novel glutamate-based therapeutic approach for post-traumatic brain injury anxiety and social impairment
Published in Translational psychiatry (04-02-2023)“…Traumatic brain injury (TBI) is a serious condition that is associated with an increased risk of severe, long-term psychiatric consequences. Drugs that target…”
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Blood Glutamate Scavenging With Pyruvate as a Novel Preventative and Therapeutic Approach for Depressive-Like Behavior Following Traumatic Brain Injury in a Rat Model
Published in Frontiers in neuroscience (14-02-2022)“…Depression is a common and serious complication following traumatic brain injury (TBI). Both depression and TBI have independently been associated with…”
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10
A Novel Histological Technique to Assess Severity of Traumatic Brain Injury in Rodents: Comparisons to Neuroimaging and Neurological Outcomes
Published in Frontiers in neuroscience (13-10-2021)“…Here we evaluate an alternative protocol to histologically examine blood-brain barrier (BBB) breakdown, brain edema, and lesion volume following traumatic…”
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Synthesis and structure of 3-substituted 1,5-dinitro-1,3,5-triazepanes
Published in Chemistry of heterocyclic compounds (New York, N.Y. 1965) (01-09-2022)“…A method has been optimized for the condensation of ethylenedinitroamine with aliphatic amines and formalaldehyde, leading to the formation of…”
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12
Urine flow rate monitoring in hypovolemic multiple trauma patients
Published in World journal of emergency surgery (18-08-2017)“…The urine output is an important clinical parameter of renal function and blood volume status, especially in critically ill multiple trauma patients. In the…”
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The clinical significance of hyperglycemia in nondiabetic critically ill multiple trauma patients
Published in Therapeutic advances in endocrinology and metabolism (01-08-2018)“…Background: Information is inconsistent regarding the clinical role of acute elevations of blood glucose level secondary to hospital-acquired infections in…”
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14
Invasive Candida Infection after Upper Gastrointestinal Tract Surgery for Gastric Cancer
Published in International Journal of Surgical Oncology (01-01-2017)“…Upper gastrointestinal tract (GIT) surgical procedures are more likely to cause nosocomial Candida peritonitis than lower GIT procedures and they thus…”
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BODY TEMPERATURE VARIATION AFTER PACKED CELL TRANSFUSION IN ADULT PATIENTS WITH SEPSIS—WHERE WILL THE PENDULUM STOP?
Published in Shock (Augusta, Ga.) (01-06-2023)“…Background : Critically ill patients with sepsis often require packed cell transfusions (PCTs). Packed cell transfusion causes changes in body's core…”
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The effect of pyruvate on the development and progression of post-stroke depression: A new therapeutic approach
Published in Neuropharmacology (01-09-2019)“…Post-stroke depression (PSD) is a common and serious complication following stroke. Both stroke and depression have independently been associated with…”
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Body temperature variation following packed cell transfusion in adult patients with sepsis – Where will the pendulum stop?
Published in Shock (Augusta, Ga.) (01-05-2023)Get full text
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18
Establishment of novel technical methods for evaluating brain edema and lesion volume in stroked rats: A standardization of measurement procedures
Published in Brain research (01-09-2019)“…•We demonstrated the efficiency of our MRI protocol for clinical scanner to evaluate infarct zone and edema in stroked rats.•Our results suggest that a…”
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19
The effect of prophylactic use of tranexamic acid for cesarean section
Published in The journal of maternal-fetal & neonatal medicine (01-01-2022)“…Treatment with tranexamic acid (TxA) significantly reduces maternal death due to postpartum hemorrhage. There is increasing interest in whether it can also be…”
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Assessing Dominant-Submissive Behavior in Adult Rats Following Traumatic Brain Injury
Published in Journal of visualized experiments (16-12-2022)“…Competition over resources such as food, territory, and mates significantly influences relationships within animal species and is mediated through social…”
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