Search Results - "Frank, C B"

Analysis of change in gait in the ovine stifle: normal, injured, and anterior cruciate ligament reconstructed by Heard, B J, Beveridge, J E, Atarod, M, O'Brien, E J, Rolian, C, Frank, C B, Hart, D A, Shrive, N G

“…Many patients who undergo anterior cruciate ligament (ACL) reconstructive surgery develop post-traumatic osteoarthritis (PTOA). ACL reconstructive surgery may…”
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New understanding of the complex structure of knee menisci: Implications for injury risk and repair potential for athletes by Rattner, J. B., Matyas, J. R., Barclay, L., Holowaychuk, S., Sciore, P., Lo, I. K. Y., Shrive, N. G., Frank, C. B., Achari, Y., Hart, D. A.

“…Menisci help maintain the structural integrity of the knee. However, the poor healing potential of the meniscus following a knee injury can not only end a…”
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Rapid isolation of total RNA from small samples of hypocellular, dense connective tissues by Reno, C, Marchuk, L, Sciore, P, Frank, C B, Hart, D A

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Gene intervention in ligament and tendon: current status, challenges, future directions by Hildebrand, K A, Frank, C B, Hart, D A

“…Ligament and tendon injuries are common clinical problems. Healing of these tissues occurs, but their properties do not return to normal. This predisposes to…”
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Technical issues in using robots to reproduce joint specific gait by Rosvold, J M, Darcy, S P, Peterson, R C, Achari, Y, Corr, D T, Marchuk, L L, Frank, C B, Shrive, N G, Rosvold, Joshua M, Darcy, Shon P, Peterson, Robert C, Achari, Yamini, Corr, David T, Marchuk, Linda L, Frank, Cyril B, Shrive, Nigel G

“…Reproduction of the in vivo motions of joints has become possible with improvements in robot technology and in vivo measuring techniques. A motion analysis…”
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Ligament creep recruits fibres at low stresses and can lead to modulus-reducing fibre damage at higher creep stresses: a study in rabbit medial collateral ligament model by Thornton, G.M, Shrive, N.G, Frank, C.B

“…Ligaments are subjected to a range of loads during different activities in vivo, suggesting that they must resist creep at various stresses. Cyclic and static…”
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Altering ligament water content affects ligament pre-stress and creep behaviour by Thornton, G.M, Shrive, N.G, Frank, C.B

“…The water content of a ligament can be altered by injury and surgical intervention in vivo, and inadvertently or purposely during in vitro tests. We…”
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New perspectives on bioengineering of joint tissues: joint adaptation creates a moving target for engineering replacement tissues by Frank, C B, Shrive, N G, Boorman, R S, Lo, I K Y, Hart, D A

“…The current paradigm in tissue engineering is that "full regeneration" or "total replacement" of normal tissue is required in order to restore joint function…”
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Primary Meningeal Rhabdomyosarcoma of the Spinal Cord of a Young Dog with Neuromelanocytosis and Multiple Cutaneous Neurofibromas by Hoon-Hanks, L.L., Frank, C.B., Edmondson, E.F.

“…A 7-week-old male black Labrador retriever puppy was presented for post-mortem examination following progressive hindlimb paralysis and multiple masses within…”
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Changes of early post-traumatic osteoarthritis in an ovine model of simulated ACL reconstruction are associated with transient acute post-injury synovial inflammation and tissue catabolism by Heard, B.J, Solbak, N.M, Achari, Y, Chung, M, Hart, D.A, Shrive, N.G, Frank, C.B

“…Summary The study described here tested the hypothesis that early intra-articular inflammation is associated with the development of post-traumatic…”
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Identification of sex hormone receptors in human and rabbit ligaments of the knee by reverse transcription-polymerase chain reaction: evidence that receptors are present in tissue from both male and female subjects by Sciore, P, Frank, C B, Hart, D A

“…Gender-related factors have been attributed to observed differences in the rate of injury to ligaments (e.g., anterior cruciate ligament) between male and…”
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Immunohistochemical Detection of Pax8 and Napsin A in Canine Thyroid Tumours: Comparison with Thyroglobulin, Calcitonin and Thyroid Transcription Factor 1 by Ramos-Vara, J.A., Frank, C.B., DuSold, D., Miller, M.A.

“…Expression of thyroid transcription factor (TTF)-1 corroborates a thyroid origin of neoplasms. Thyroglobulin and calcitonin immunohistochemistry (IHC) can…”
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Malignant anal sac melanoma in dogs: eleven cases (2000 to 2015) by Vinayak, A., Frank, C. B., Gardiner, D. W., Thieman‐Mankin, K. M., Worley, D. R.

“…Objectives To report the signalment, clinical presentation, treatments pursued and outcomes of dogs with malignant anal sac melanoma. Methods Medical records…”
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A comparison of in vivo gene delivery methods for antisense therapy in ligament healing by NAKAMURA, N, TIMMERMANN, S. A, HART, D. A, KANEDA, Y, SHRIVE, N. G, SHINO, K, OCHI, T, FRANK, C. B

“…To determine the most efficient in vivo delivery method of oligonucleotides for antisense therapy in ligament healing, fluorescence-labelled phosphorothioate…”
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Healing ligaments have decreased cyclic modulus compared to normal ligaments and immobilization further compromises healing ligament response to cyclic loading by Thornton, G.M, Shrive, N.G, Frank, C.B

“…Ligaments help maintain joint stability by resisting excessive strain during the repetitive loading experienced during daily activity. Healing ligaments may be…”
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Immunohistochemical Expression of Melanocytic Antigen PNL2, Melan A, S100, and PGP 9.5 in Equine Melanocytic Neoplasms by Ramos-Vara, J. A., Frank, C. B., DuSold, D., Miller, M. A.

“…The immunoreactivity of PNL2, Melan A, and protein gene product (PGP) 9.5 was compared with that of S100 protein in 50 formalin-fixed, paraffin-embedded equine…”
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Parametric representation and screening of knee joint vibroarthrographic signals by Rangayyan, R.M., Krishnan, S., Bell, G.D., Frank, C.B., Ladly, K.O.

“…The authors have been investigating analysis of knee joint vibration or vibroarthrographic (VAG) signals as a potential tool for noninvasive diagnosis and…”
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Cartilage boundary lubrication of ovine synovial fluid following anterior cruciate ligament transection: a longitudinal study by Atarod, M, Ludwig, T.E, Frank, C.B, Schmidt, T.A, Shrive, N.G

“…Summary Objective To assess ovine synovial fluid (oSF) from different post-injury time points for (1) proteoglycan-4 (PRG4) and hyaluronan (HA) concentration,…”
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Strength of medial structures of the knee joint are decreased by isolated injury to the medial collateral ligament and subsequent joint immobilization by Thornton, G.M., Johnson, J.C., Maser, R.V., Marchuk, L.L., Shrive, N.G., Frank, C.B.

“…Past studies of the healing of the medial collateral ligament (MCL) in animal models have been conducted over a variety of healing intervals, some as early as…”
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BCL2 and MYC are expressed at high levels in canine diffuse large B‐cell lymphoma but are not predictive for outcome in dogs treated with CHOP chemotherapy by Curran, K. M., Schaffer, P. A., Frank, C. B., Lana, S. E., Hamil, L. E., Burton, J. H., Labadie, J., Ehrhart, E. J., Avery, P. R.

“…Diffuse large B‐cell lymphoma (DLBCL) is the most common haematopoietic malignancy in dogs. Recently, MYC and BCL2 expression levels determined with…”
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