Search Results - "Frank, A. L."
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1
Circadian clocks and insulin resistance
Published in Nature reviews. Endocrinology (01-02-2019)“…Insulin resistance is a main determinant in the development of type 2 diabetes mellitus and a major cause of morbidity and mortality. The circadian timing…”
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2
Impact of circadian disruption on glucose metabolism: implications for type 2 diabetes
Published in Diabetologia (01-03-2020)“…The circadian system generates endogenous rhythms of approximately 24 h, the synchronisation of which are vital for healthy bodily function. The timing of many…”
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3
Ghrelin is impacted by the endogenous circadian system and by circadian misalignment in humans
Published in International Journal of Obesity (01-08-2019)“…The human circadian system regulates hunger independently of behavioral factors, resulting in a trough in the biological morning and a peak in the biological…”
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4
Effects of the Internal Circadian System and Circadian Misalignment on Glucose Tolerance in Chronic Shift Workers
Published in The journal of clinical endocrinology and metabolism (01-03-2016)“…Context: Shift work is a risk factor for diabetes. The separate effects of the endogenous circadian system and circadian misalignment (ie, misalignment between…”
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5
Effects of circadian misalignment on cognition in chronic shift workers
Published in Scientific reports (24-01-2019)“…Shift work is associated with increased human operational errors, presumably due to the circadian timing system that inhibits optimal cognitive function during…”
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6
Daily circadian misalignment impairs human cognitive performance task-dependently
Published in Scientific reports (14-02-2018)“…Shift work increases the risk for human errors, such that drowsiness due to shift work has contributed to major industrial disasters, including Space Shuttle…”
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7
CIRCUST: A novel methodology for temporal order reconstruction of molecular rhythms; validation and application towards a daily rhythm gene expression atlas in humans
Published in PLoS computational biology (28-09-2023)“…The circadian system drives near-24-h oscillations in behaviors and biological processes. The underlying core molecular clock regulates the expression of other…”
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8
Effects of Shift Work on the Eating Behavior of Police Officers on Patrol
Published in Nutrients (04-04-2020)“…Recent studies indicate that the timing of food intake can significantly affect metabolism and weight management. Workers operating at atypical times of the…”
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9
Effects of circadian disruption on the cardiometabolic system
Published in Reviews in endocrine & metabolic disorders (01-12-2009)“…The presence of day-night variations in cardiovascular and metabolic functioning is well known. However, only recently it has been shown that cardiovascular…”
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10
Sex-dependent link between circadian misalignment and adiposity
Published in Nature reviews. Endocrinology (01-01-2020)“…A cross-sectional study shows that proxies of circadian misalignment, such as late chronotype and social jet lag, are associated with increased adiposity in…”
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11
A healthy lifestyle — reducing T2DM risk in shift workers?
Published in Nature reviews. Endocrinology (01-04-2019)“…A recent study shows that a history of rotating night-shift work and an unhealthy lifestyle are associated with increased risk of type 2 diabetes mellitus…”
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12
Meal timing and obesity: interactions with macronutrient intake and chronotype
Published in International Journal of Obesity (01-09-2019)“…Background Timing of dietary intake may play a role in obesity. However, previous studies produced mixed findings possibly due to inconsistent approaches to…”
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13
Caloric and Macronutrient Intake Differ with Circadian Phase and between Lean and Overweight Young Adults
Published in Nutrients (11-03-2019)“…The timing of caloric intake is a risk factor for excess weight and disease. Growing evidence suggests, however, that the impact of caloric consumption on…”
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14
Circadian misalignment increases cardiovascular disease risk factors in humans
Published in Proceedings of the National Academy of Sciences - PNAS (08-03-2016)“…Shift work is a risk factor for hypertension, inflammation, and cardiovascular disease. This increased risk cannot be fully explained by classic risk factors…”
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Longitudinal associations of diurnal rest-activity rhythms with fatigue, insomnia, and health-related quality of life in survivors of colorectal cancer up to 5 years post-treatment
Published in The international journal of behavioral nutrition and physical activity (02-05-2024)“…There is a growing population of survivors of colorectal cancer (CRC). Fatigue and insomnia are common symptoms after CRC, negatively influencing…”
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16
Plasticity of the intrinsic period of the human circadian timing system
Published in PloS one (08-08-2007)“…Human expeditions to Mars will require adaptation to the 24.65-h Martian solar day-night cycle (sol), which is outside the range of entrainment of the human…”
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17
Genetics of circadian rhythms and sleep in human health and disease
Published in Nature reviews. Genetics (01-01-2023)“…Circadian rhythms and sleep are fundamental biological processes integral to human health. Their disruption is associated with detrimental physiological…”
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Fractal patterns of neural activity exist within the suprachiasmatic nucleus and require extrinsic network interactions
Published in PloS one (20-11-2012)“…The mammalian central circadian pacemaker (the suprachiasmatic nucleus, SCN) contains thousands of neurons that are coupled through a complex network of…”
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Synthesis and Characterization of a Brønsted Pair Functionalized Shape-Persistent Macrocycle
Published in Organic letters (04-09-2015)“…The first shape-persistent macrocycle 1 offering a Brønsted pair functionalized interior is described. Via postcyclization transformation, this heterosequenced…”
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Best Time of Day for Strength and Endurance Training to Improve Health and Performance? A Systematic Review with Meta-analysis
Published in Sports medicine - open (19-05-2023)“…Background Current recommendations for physical exercise include information about the frequency, intensity, type, and duration of exercise. However, to date,…”
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