Search Results - "Frangos, Sara M."

The Purinome and the preBötzinger Complex - A Ménage of Unexplored Mechanisms That May Modulate/Shape the Hypoxic Ventilatory Response by Reklow, Robert J, Alvares, Tucaaue S, Zhang, Yong, Miranda Tapia, Ana P, Biancardi, Vivian, Katzell, Alexis K, Frangos, Sara M, Hansen, Megan A, Toohey, Alexander W, Cass, Carol E, Young, James D, Pagliardini, Silvia, Boison, Detlev, Funk, Gregory D

“…Exploration of purinergic signaling in brainstem homeostatic control processes is challenging the traditional view that the biphasic hypoxic ventilatory…”
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Revisiting the contribution of mitochondrial biology to the pathophysiology of skeletal muscle insulin resistance by Frangos, Sara M, Bishop, David J, Holloway, Graham P

“…While the etiology of type 2 diabetes is multifaceted, the induction of insulin resistance in skeletal muscle is a key phenomenon, and impairments in insulin…”
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Fatiguing high-intensity intermittent exercise depresses maximal Na+-K+-ATPase activity in human skeletal muscle assessed using a novel NADH-coupled assay by Vigh-Larsen, Jeppe F., Frangos, Sara M., Overgaard, Kristian, Holloway, Graham P., Mohr, Magni

“…Abstract The Na + -K + -ATPase is a critical regulator of ion homeostasis during contraction, buffering interstitial K + accumulation, which is linked to…”
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Acidosis attenuates CPT-I-supported bioenergetics as a potential mechanism limiting lipid oxidation by Frangos, Sara M., DesOrmeaux, Geneviève J., Holloway, Graham P.

“…Fuel interactions in contracting muscle represent a complex interplay between enzymes regulating carbohydrate and fatty acid catabolism, converging in the…”
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GDF15 promotes weight loss by enhancing energy expenditure in muscle by Wang, Dongdong, Townsend, Logan K., DesOrmeaux, Geneviève J., Frangos, Sara M., Batchuluun, Battsetseg, Dumont, Lauralyne, Kuhre, Rune Ehrenreich, Ahmadi, Elham, Hu, Sumei, Rebalka, Irena A., Gautam, Jaya, Jabile, Maria Joy Therese, Pileggi, Chantal A., Rehal, Sonia, Desjardins, Eric M., Tsakiridis, Evangelia E., Lally, James S. V., Juracic, Emma Sara, Tupling, A. Russell, Gerstein, Hertzel C., Paré, Guillaume, Tsakiridis, Theodoros, Harper, Mary-Ellen, Hawke, Thomas J., Speakman, John R., Blondin, Denis P., Holloway, Graham P., Jørgensen, Sebastian Beck, Steinberg, Gregory R.

“…Caloric restriction that promotes weight loss is an effective strategy for treating non-alcoholic fatty liver disease and improving insulin sensitivity in…”
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Independent, but not co-supplementation, with nitrate and resveratrol improves glucose tolerance and reduces markers of cellular stress in high-fat-fed male mice by Handy, Rachel M, DesOrmeaux, Geneviève J, Barbeau, Pierre-Andre, Frangos, Sara M, Holloway, Graham P

“…Independent supplementation with nitrate (NIT) and resveratrol (RSV) enriches various aspects of mitochondrial biology in key metabolic tissues. Although RSV…”
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Dietary nitrate preserves mitochondrial bioenergetics and mitochondrial protein synthesis rates during short-term immobilization in mice by Petrick, Heather L, Handy, Rachel M, Vachon, Bayley, Frangos, Sara M, Holwerda, Andrew M, Gijsen, Annemarie P, Senden, Joan M, van Loon, Luc J C, Holloway, Graham P

“…Skeletal muscle disuse reduces muscle protein synthesis rates and induces atrophy, events associated with decreased mitochondrial respiration and increased…”
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Skeletal muscle AMPK activation: mounting evidence against a role in substrate utilization during acute exercise by Frangos, Sara M., DesOrmeaux, Geneviève J., Petrick, Heather L.

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Altered carbohydrate oxidation during exercise in overreached endurance athletes is applicable to training monitoring with continuous glucose monitors by Coates, Alexandra M., Thompson, Kyle M. A., Grigore, Monica M., Baker, Ryleigh E., Pignanelli, Christopher, Robertson, Alexa A., Frangos, Sara M., Cheung, Christian P., Burr, Jamie F.

“…Purpose The purpose of the study was to investigate whether carbohydrate utilization is altered during exercise in overreached endurance athletes and examine…”
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Developmental Changes in the Role of Adenosine Clearance Mechanisms in Modulating the Activity of the preBötzinger Complex Inspiratory Network Under Basal and Hypoxic Conditions by Reklow, Robert Jeffrey, Alvares, Tucaauê S., Frangos, Sara M., Hansen, Megan A., Funk, Gregory D.

“…Exposure to low oxygen (hypoxia) evokes a biphasic hypoxic ventilatory response (HVR) characterized by a carotid‐body‐mediated increase in ventilation followed…”
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Impact of Equilibrative Nucleoside (Adenosine) Transporters on the preBötzinger Complex Inspiratory Network and the Hypoxic Ventilatory Response in Newborn Mice by Reklow, Robert J., Hansen, Megan A., Frangos, Sara M., Alvares, Tucaauê S., Funk, Gregory D.

“…Exposure to low oxygen (hypoxia) evokes a biphasic hypoxic ventilatory response (HVR) comprising of an initial increase in ventilation followed by a secondary…”
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