Search Results - "Franek, Miloslav"
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Parallel fluorescence and phosphorescence monitoring of singlet oxygen photosensitization in rats
Published in Journal of innovative optical health science (01-11-2015)“…The time- and spectral-resolved set-up for measurements of weak infrared luminescence of photosensitizers (PSs) and singlet oxygen using optical lightguides…”
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2
Mouse glutamate carboxypeptidase II (GCPII) has a similar enzyme activity and inhibition profile but a different tissue distribution to human GCPII
Published in FEBS open bio (01-09-2017)“…Glutamate carboxypeptidase II (GCPII), also known as prostate‐specific membrane antigen (PSMA) or folate hydrolase, is a metallopeptidase expressed…”
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3
PIP2 and PIP3 interact with N-terminus region of TRPM4 channel
Published in Biophysical chemistry (01-10-2015)“…The transient receptor potential melastatin 4 (TRPM4) is a calcium-activated non-selective ion channel broadly expressed in a variety of tissues. Receptor has…”
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4
Motor cortex stimulation in rats with chronic constriction injury
Published in Experimental brain research (01-02-2008)“…Motor cortex stimulation (MCS) has gained a significant role in treatment of neuropathic pain. In order to evaluate effect of MCS in experimental animals we…”
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5
Role of oxidative stress in animal model of visceral pain
Published in Neuroscience letters (21-06-2010)“…Reactive oxygen species play an important role both in physiological and pathophysiological reactions. The aim of this study was to determine the role of free…”
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Mapping the Agonist-binding Site of GABAB Type 1 Subunit Sheds Light on the Activation Process of GABABReceptors
Published in The Journal of biological chemistry (29-12-2000)“…The γ-amino-n-butyric acid type B (GABAB) receptor is composed of two subunits, GABAB1 and GABAB2, belonging to the family 3 heptahelix receptors. These…”
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7
Characterization of the part of N-terminal PIP2 binding site of the TRPM1 channel
Published in Biophysical chemistry (01-12-2015)“…Transient receptor potential melastatin-1 (TRPM1) is a calcium channel that is essential for the depolarization of photo-responsive retinal bipolar cells, but…”
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8
Different transfer of nociceptive sensitivity from rats with postnatal hippocampal lesions to control rats
Published in The European journal of neuroscience (01-07-2007)“…Hippocampal lesions in newborn rats alter the development of mechanisms involved in the processing of nociception. The hippocampal lesion was induced by the…”
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Role of GABA(B) receptor agonist baclofen in acute pain modulation during the early postnatal period
Published in Pharmacology (2009)“…Baclofen, a specific GABA(B) receptor agonist, is used to treat spasticity and its off-label use includes the treatment of pain. The aim of this study was to…”
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10
Poly(d,l-lactide)/polyethylene glycol micro/nanofiber mats as paclitaxel-eluting carriers: preparation and characterization of fibers, in vitro drug release, antiangiogenic activity and tumor recurrence prevention
Published in Materials Science & Engineering C (01-05-2019)“…Poly(d,l-lactide)/polyethylene glycol (PLA/PEG) micro/nanofibers loaded with paclitaxel (PTX, 10 wt%) were prepared by needless electrospinning technology,…”
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11
Mapping the agonist-binding site of GABAB type 1 subunit sheds light on the activation process of GABAB receptors
Published in The Journal of biological chemistry (29-12-2000)“…The gamma-amino-n-butyric acid type B (GABA(B)) receptor is composed of two subunits, GABA(B)1 and GABA(B)2, belonging to the family 3 heptahelix receptors…”
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12
The heteromeric GABA-B receptor recognizes G-protein α subunit C-termini
Published in Neuropharmacology (01-11-1999)“…The recently cloned GABA-B receptors are related to the metabotropic glutamate receptors (mGlu receptors), the Ca 2+-sensing receptor and one group of…”
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13
Self-mutilation in young rats after dorsal rhizotomy
Published in Neuro-endocrinology letters (01-02-2005)“…The aim of the study was to describe the development of self-mutilation after extensive dorsal rhizotomy of the brachial plexus performed during early ontogeny…”
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Paradoxical firing of thalamic neurons under neuropathic pain state in rats
Published in Neuro-endocrinology letters (01-12-2004)“…A novel evaluative approach was used to determine single unit activities of non-bursting intralaminar thalamic nuclei under neuropathic pain state following…”
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GABAB receptor agonist baclofen has non-specific antinociceptive effect in the model of peripheral neuropathy in rat
Published in Physiological research (2004)“…Baclofen, which is a specific agonist of the metabotropic GABA(B) receptor, is used in clinical practice for the treatment of spasticity of skeletal muscles…”
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