Search Results - "Franco, Rose Ann G"
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Microtissue Culture Provides Clarity on the Relative Chondrogenic and Hypertrophic Response of Bone-Marrow-Derived Stromal Cells to TGF-β1, BMP-2, and GDF-5
Published in Cells (Basel, Switzerland) (23-12-2023)“…Chondrogenic induction of bone-marrow-derived stromal cells (BMSCs) is typically accomplished with medium supplemented with growth factors (GF) from the…”
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2
Method for manufacture and cryopreservation of cartilage microtissues
Published in Journal of tissue engineering (01-01-2023)“…The financial viability of a cell and tissue-engineered therapy may depend on the compatibility of the therapy with mass production and cryopreservation…”
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Inhibition of BMP signaling with LDN 193189 can influence bone marrow stromal cell fate but does not prevent hypertrophy during chondrogenesis
Published in Stem cell reports (08-03-2022)“…Bone morphogenetic protein (BMP) cascades are upregulated during bone marrow-derived stromal cell (BMSC) chondrogenesis, contributing to hypertrophy and…”
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A tumour-spheroid manufacturing and cryopreservation process that yields a highly reproducible product ready for direct use in drug screening assays
Published in Journal of the Royal Society interface (11-10-2023)“…If it were possible to purchase tumour-spheroids as a standardised product, ready for direct use in assays, this may contribute to greater research…”
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SP7 gene silencing dampens bone marrow stromal cell hypertrophy, but it also dampens chondrogenesis
Published in Journal of tissue engineering (01-01-2023)“…For bone marrow stromal cells (BMSC) to be useful in cartilage repair their propensity for hypertrophic differentiation must be overcome. A single day of…”
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Draft Genome Sequence of Bacillus lehensis M136, Isolated from the Manleluag Hyperalkaline Spring in Pangasinan, Philippines
Published in Microbiology resource announcements (28-03-2019)“…Here, we report the draft whole-genome sequence of M136, isolated from a hyperalkaline spring located in Pangasinan, Philippines. From 24 scaffolds, the total…”
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gene silencing dampens bone marrow stromal cell hypertrophy, but it also dampens chondrogenesis
Published in Journal of tissue engineering (01-06-2023)“…For bone marrow stromal cells (BMSC) to be useful in cartilage repair their propensity for hypertrophic differentiation must be overcome. A single day of…”
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