Search Results - "Franco, Melissa"
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First-Line Therapy for Type 2 Diabetes With Sodium-Glucose Cotransporter-2 Inhibitors and Glucagon-Like Peptide-1 Receptor Agonists : A Cost-Effectiveness Study
Published in Annals of internal medicine (01-10-2022)“…Guidelines recommend sodium-glucose cotransporter-2 (SGLT2) inhibitors and glucagon-like peptide-1 (GLP1) receptor agonists as second-line therapy for patients…”
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Pragmatic Clinical Trial of Population Health, Portal-Based Depression Screening: the PORTAL-Depression Study
Published in Journal of general internal medicine : JGIM (01-03-2023)“…Background A population health approach to depression screening using patient portals may be a promising strategy to proactively engage and identify patients…”
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Going beyond the individual: how state-level characteristics relate to HPV vaccine rates in the United States
Published in BMC public health (28-02-2019)“…The human papillomavirus (HPV) vaccine is an underutilized cancer control practice in the United States. Although individual contextual factors are known to…”
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Population Health Management Approach to Depression Symptom Monitoring in Primary Care via Patient Portal: A Randomized Controlled Trial
Published in American journal of medical quality (01-07-2023)“…Depression is undertreated in primary care. Using patient portals to administer regular symptom assessments could facilitate more timely care. At an urban…”
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Patient Perspectives on Portal-Based Anxiety and Depression Screening in HIV Care: A Qualitative Study Using the Consolidated Framework for Implementation Research
Published in International journal of environmental research and public health (28-05-2024)“…Electronic patient portals represent a promising means of integrating mental health assessments into HIV care where anxiety and depression are highly…”
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Are some mutations more equal than others?
Published in eLife (19-04-2023)“…A large-scale study of mutations in mitochondrial DNA has revealed a subset that do not accumulate with age…”
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A mitochondria-specific mutational signature of aging: increased rate of A > G substitutions on the heavy strand
Published in Nucleic acids research (14-10-2022)“…The mutational spectrum of the mitochondrial DNA (mtDNA) does not resemble any of the known mutational signatures of the nuclear genome and variation in mtDNA…”
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Implementation of an EHR-integrated web-based depression assessment in primary care: PORTAL-Depression
Published in JAMIA open (01-10-2024)“…To integrate a computerized adaptive test for depression into the electronic health record (EHR) and establish systems for administering assessments in-clinic…”
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Toward optimal implementation of cancer prevention and control programs in public health: a study protocol on mis-implementation
Published in Implementation science : IS (23-03-2018)“…Much of the cancer burden in the USA is preventable, through application of existing knowledge. State-level funders and public health practitioners are in…”
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Population-Level Portal-Based Anxiety and Depression Screening Perspectives in HIV Care Clinicians: Qualitative Study Using the Consolidated Framework for Implementation Research
Published in JMIR formative research (01-01-2024)“…Depression and anxiety are common among people with HIV and are associated with inadequate viral suppression, disease progression, and increased mortality…”
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Oral health in preschool and level of knowledge about oral hygiene of their mothers, in public and private schools in San Lorenzo, Paraguay
Published in Pediatria (Asunción) (25-10-2016)Get full text
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Mental health in the family health program: the conceptions of community agents about mental illness
Published in Revista da Escola de Enfermagem da U S P (01-12-2007)“…This study identified social representations of mental illness by community agents in a Family Health Program unit. The authors chose the qualitative approach…”
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Computational models elucidate dynamics in the intergenerational inheritance of mtDNA mutations
Published in The FASEB journal (01-05-2022)“…Mitochondria, widely studied for their crucial role in cell bioenergetics, carry independent genomes that are inherited in offspring maternally. Understanding…”
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Quasi-Mendelian paternal inheritance of mitochondrial DNA: A notorious artifact, or anticipated behavior?
Published in Proceedings of the National Academy of Sciences - PNAS (23-07-2019)Get full text
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Mitochondrial DNA replication‐related Nucleotide Patterns: Ancient ruins or living structures?
Published in The FASEB journal (01-04-2019)“…Whether mtDNA replication occurs via strand‐symmetric or strand‐asymmetric mechanism has been a matter of controversy. The asymmetric model predicts special…”
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Can detrimental mtDNA mutations be under positive selection in the germline?
Published in The FASEB journal (01-04-2020)“…Abstract only…”
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777-P: Efficacy of SGLT2 Inhibitors and GLP1-Receptor Agonists in Asians with Type 2 Diabetes: A Systemic Review and Meta-analysis
Published in Diabetes (New York, N.Y.) (01-06-2021)“…Background: Clinical trials of SGLT2Is and GLP1RAs have shown improved outcomes in patients with type 2 diabetes, but comprehensive data of their effectiveness…”
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886-P: Development and Validation of the Diabetes Outcome Model for the U.S. (DOMUS)
Published in Diabetes (New York, N.Y.) (01-06-2022)“…Purpose: The purpose of this study is to develop a diabetes outcomes model for the US (DOMUS) using a multi-ethnic, real-world-data cohort of newly diagnosed…”
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The Longer-Term Benefits and Harms of Glucagon-Like Peptide-1 Receptor Agonists: a Systematic Review and Meta-Analysis
Published in Journal of general internal medicine : JGIM (01-02-2022)“…Background Previous meta-analyses of the benefits and harms of glucagon-like peptide-1 receptor agonists (GLP1RAs) have been limited to specific outcomes and…”
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Reanalysis of mtDNA mutations of human primordial germ cells (PGCs) reveals NUMT contamination and suggests that selection in PGCs may be positive
Published in Mitochondrion (01-01-2024)“…The resilience of the mitochondrial genome (mtDNA) to a high mutational pressure depends, in part, on negative purifying selection in the germline. A paradigm…”
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