Search Results - "Franco, Lori"
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Synergistic drug combinations designed to fully suppress SARS-CoV-2 in the lung of COVID-19 patients
Published in PloS one (10-11-2022)“…Despite new antivirals are being approved against SARS-CoV-2 they suffer from significant constraints and are not indicated for hospitalized patients, who are…”
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Visible Light Activation of Virucidal Surfaces Empowered by Pro‐Oxidant Carbon Dots
Published in Advanced functional materials (01-11-2024)“…The scientific community is actively engaged in the development of innovative nanomaterials with broad‐spectrum virucidal properties, particularly those…”
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SARS-CoV-2 Inactivation in Aerosol by Means of Radiated Microwaves
Published in Viruses (27-06-2023)“…Coronaviruses are a family of viruses that cause disease in mammals and birds. In humans, coronaviruses cause infections on the respiratory tract that can be…”
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Reply to Taylor et al. Comment on “Manna et al. SARS-CoV-2 Inactivation in Aerosol by Means of Radiated Microwaves. Viruses 2023, 15, 1443”
Published in Viruses (18-10-2023)“…SARS-CoV-2 is inactivated in aerosol (its primary mode of transmission) by means of radiated microwaves at frequencies that have been experimentally…”
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Precision COVID-19 Vaccine with Companion Diagnostics
Published in Precision nanomedicine (10-04-2020)“…<img src=” https://s3.amazonaws.com/production.scholastica/article/12561/medium/prnano_412020_figure_1.jpg?1586516744”> Although disease enhancement by…”
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Single DermaVir immunization: dose-dependent expansion of precursor/memory T cells against all HIV antigens in HIV-1 infected individuals
Published in PloS one (09-05-2012)“…The GIHU004 study was designed to evaluate the safety and immunogenicity of three doses of DermaVir immunization in HIV-infected subjects on fully suppressive…”
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In Vitro Antiviral Activity of Hyperbranched Poly-L-Lysine Modified by L-Arginine against Different SARS-CoV-2 Variants
Published in Nanomaterials (Basel, Switzerland) (01-12-2023)“…The emergence of SARS-CoV-2 variants requires close monitoring to prevent the reoccurrence of a new pandemic in the near future. The Omicron variant, in…”
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Structured Treatment Interruptions for the Management of HIV Infection
Published in JAMA : the journal of the American Medical Association (19-12-2001)“…Antiretroviral drugs constitute a milestone in the treatment of human immunodeficiency virus (HIV) infection; however, emerging problems limit their long-term…”
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ViroStatics Testing Capabilities to Determine Efficacy of Drugs, Disinfectants or Devices against SARS-CoV-2
Published in Precision nanomedicine (27-06-2021)“…ViroStatics is a privately held small pharmaceutical company dedicated to discovering and developing novel compounds for a multifaceted treatment of cancers…”
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VS411 reduced immune activation and HIV-1 RNA levels in 28 days: randomized proof-of-concept study for antiviral-hyperactivation limiting therapeutics
Published in PloS one (19-10-2012)“…A new class of antiretrovirals, AntiViral-HyperActivation Limiting Therapeutics (AV-HALTs), has been proposed as a disease-modifying therapy to both reduce…”
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DermaVir: A Novel Topical Vaccine for HIV/AIDS
Published in Journal of investigative dermatology (01-01-2005)“…Human immunodeficiency virus (HIV) vaccines have the potential to improve antiretroviral drug treatment by inducing cytotoxic killing of HIV-infected cells…”
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Control of SIV Rebound through Structured Treatment Interruptions during Early Infection
Published in Science (American Association for the Advancement of Science) (24-11-2000)“…In a randomized controlled trial with acute simian immunodeficiency virus (SIV)-infected macaques, both highly active antiretroviral therapy (HAART) and HAART…”
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Beneficial effect of TRAIL on HIV burden, without detectable immune consequences
Published in PloS one (28-08-2008)“…During uncontrolled HIV disease, both TNF-related apoptosis inducing ligand (TRAIL) and TRAIL receptor expression are increased. Enhanced TRAIL sensitivity is…”
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Hydroxyurea as an Inhibitor of Human Immunodeficiency Virus-Type 1 Replication
Published in Science (American Association for the Advancement of Science) (04-11-1994)“…Hydroxyurea, a drug widely used in therapy of several human diseases, inhibits deoxynucleotide synthesis-and, consequently, DNA synthesis-by blocking the…”
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Low Levels of Deoxynucleotides in Peripheral Blood Lymphocytes: A Strategy to Inhibit Human Immunodeficiency Virus Type 1 Replication
Published in Proceedings of the National Academy of Sciences - PNAS (01-10-1993)“…Human immunodeficiency virus type 1 (HIV-1) viral DNA synthesis in quiescent and activated peripheral blood lymphocytes (PBLs) was studied. Incomplete viral…”
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Structured treatment interruptions as a potential alternative therapeutic regimen for HIV-infected patients: a review of recent clinical data and future prospects
Published in Journal of antimicrobial chemotherapy (01-08-2002)“…Highly active antiretroviral therapy (HAART) allows for substantial control of HIV replication in vivo, and has caused a significant decline in morbidity and…”
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Mutations in the pol Gene of Human Immunodeficiency Virus Type 1 in Infected Patients Receiving Didanosine and Hydroxyurea Combination Therapy
Published in The Journal of infectious diseases (01-10-1997)“…The pattern of mutations in the reverse transcriptase (RT) of human immunodeficiency virus type 1 (HIV-1) strains that confer resistance to didanosine (ddI)…”
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DermaVir: a plasmid DNA-based nanomedicine therapeutic vaccine for the treatment of HIV/AIDS
Published in Expert review of vaccines (01-10-2011)“…The HIV global pandemic continues to rage with over 33 million people living with the disease. Although multidrug therapy has improved the prognosis for those…”
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CD4^+ T cell-mediated presentation of non-infectious HIV-1 virion antigens to HIV-specific CD8^+ T cells
Published in Chinese medical journal (05-10-2006)“…Background The mechanism of chronic immune activation and impairment of HIV-specific immune responses during chronic infection is not fully understood…”
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Induction of Potent Human Immunodeficiency Virus Type 1-Specific T-Cell-Restricted Immunity by Genetically Modified Dendritic Cells
Published in Journal of Virology (01-08-2001)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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