Search Results - "Franco, Alessio"

Imaging Enterobacterales infections in patients using pathogen-specific positron emission tomography by Ordonez, Alvaro A, Wintaco, Luz M, Mota, Filipa, Restrepo, Andres F, Ruiz-Bedoya, Camilo A, Reyes, Carlos F, Uribe, Luis G, Abhishek, Sudhanshu, D'Alessio, Franco R, Holt, Daniel P, Dannals, Robert F, Rowe, Steven P, Castillo, Victor R, Pomper, Martin G, Granados, Ulises, Jain, Sanjay K

“…represent the largest group of bacterial pathogens in humans and are responsible for severe, deep-seated infections, often resulting in sepsis or death. They…”
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A case report on dietary needs of the rowing athlete winner of the triple crown by Ficarra, Giovanni, Mannucci, Carmen, Franco, Alessio, Bitto, Alessandra, Trimarchi, Fabio, Di Mauro, Debora

“…Sports nutrition is a topic that is often misinterpreted and sometimes abused. The often-used "shot-gun" method to meeting caloric needs by simply increasing…”
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Mouse Models of Acute Lung Injury and ARDS by D'Alessio, Franco R

“…The acute respiratory distress syndrome (ARDS) is a devastating illness characterized by severe hypoxemia and diffuse alveolar damage. Direct lung infection is…”
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Reparative T lymphocytes in organ injury by D'Alessio, Franco R, Kurzhagen, Johanna T, Rabb, Hamid

“…Acute organ injuries such as acute cerebrovascular accidents, myocardial infarction, acute kidney injury, acute lung injury, and others are among the leading…”
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Diverse macrophage populations mediate acute lung inflammation and resolution by Aggarwal, Neil R, King, Landon S, D'Alessio, Franco R

“…Acute respiratory distress syndrome (ARDS) is a devastating disease with distinct pathological stages. Fundamental to ARDS is the acute onset of lung…”
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COVID-19 and myeloid cells: complex interplay correlates with lung severity by D'Alessio, Franco R, Heller, Nicola M

“…COVID-19 spans a wide range of symptoms, sometimes with profound immune system involvement. How immune cell subsets change during the disease course and with…”
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The Transcriptional Signature in Alveolar Macrophages Dictates Acute Respiratory Distress Outcomes by Tejwani, Vickram, D'Alessio, Franco R

“…[...]it reinforces the need to better phenotype patients with ARDS. [...]macrophage transcriptional profiles require confirmation by protein expression and…”
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Immune Checkpoint Inhibitor Use in Sepsis: Monitoring Immune Checkpoint Inhibitor Toxicity by Suresh, Karthik, D’Alessio, Franco

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Regulatory T Cells for Treating Patients With COVID-19 and Acute Respiratory Distress Syndrome: Two Case Reports by Gladstone, Douglas E, Kim, Bo Soo, Mooney, Kathy, Karaba, Andrew H, D'Alessio, Franco R

“…The study on the outcomes in two patients with COVID-19 and acute respiratory distress syndrome (ARDS) who were treated with T regulatory cells (Tregs)…”
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Metabolic programs define dysfunctional immune responses in severe COVID-19 patients by Thompson, Elizabeth A., Cascino, Katherine, Ordonez, Alvaro A., Zhou, Weiqiang, Vaghasia, Ajay, Hamacher-Brady, Anne, Brady, Nathan R., Sun, Im-Hong, Wang, Rulin, Rosenberg, Avi Z., Delannoy, Michael, Rothman, Richard, Fenstermacher, Katherine, Sauer, Lauren, Shaw-Saliba, Kathyrn, Bloch, Evan M., Redd, Andrew D., Tobian, Aaron A.R., Horton, Maureen, Smith, Kellie, Pekosz, Andrew, D’Alessio, Franco R., Yegnasubramanian, Srinivasan, Ji, Hongkai, Cox, Andrea L., Powell, Jonathan D.

“…It is unclear why some SARS-CoV-2 patients readily resolve infection while others develop severe disease. By interrogating metabolic programs of immune cells…”
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Regulatory T cells as immunotherapy by Singer, Benjamin D, King, Landon S, D'Alessio, Franco R

“…Regulatory T cells (Tregs) suppress exuberant immune system activation and promote immunologic tolerance. Because Tregs modulate both innate and adaptive…”
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CD4+CD25+Foxp3+ Tregs resolve experimental lung injury in mice and are present in humans with acute lung injury by D'Alessio, Franco R, Tsushima, Kenji, Aggarwal, Neil R, West, Erin E, Willett, Matthew H, Britos, Martin F, Pipeling, Matthew R, Brower, Roy G, Tuder, Rubin M, McDyer, John F, King, Landon S

“…Acute lung injury (ALI) is characterized by rapid alveolar injury, inflammation, cytokine induction, and neutrophil accumulation. Although early events in the…”
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Bet-hedging antimicrobial strategies in macrophage phagosome acidification drive the dynamics of Cryptococcus neoformans intracellular escape mechanisms by Dragotakes, Quigly, Jacobs, Ella, Ramirez, Lia Sanchez, Yoon, Olivia Insun, Perez-Stable, Caitlin, Eden, Hope, Pagnotta, Jenlu, Vij, Raghav, Bergman, Aviv, D'Alessio, Franco, Casadevall, Arturo

“…The fungus Cryptococcus neoformans is a major human pathogen with a remarkable intracellular survival strategy that includes exiting macrophages through…”
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Experimental Model to Evaluate Resolution of Pneumonia by Villabona-Rueda, Andres, Wang, Daniel, D'Alessio, Franco R

“…Acute respiratory distress syndrome (ARDS) causes acute lung injury, characterized by rapid alveolar damage and severe hypoxemia. This, in turn, leads to high…”
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Functional characterization of CD4+ T cell receptors crossreactive for SARS-CoV-2 and endemic coronaviruses by Dykema, Arbor G, Zhang, Boyang, Woldemeskel, Bezawit A, Garliss, Caroline C, Cheung, Laurene S, Choudhury, Dilshad, Zhang, Jiajia, Aparicio, Luis, Bom, Sadhana, Rashid, Rufiaat, Caushi, Justina X, Hsiue, Emily Han-Chung, Cascino, Katherine, Thompson, Elizabeth A, Kwaa, Abena K, Singh, Dipika, Thapa, Sampriti, Ordonez, Alvaro A, Pekosz, Andrew, D'Alessio, Franco R, Powell, Jonathan D, Yegnasubramanian, Srinivasan, Zhou, Shibin, Pardoll, Drew M, Ji, Hongkai, Cox, Andrea L, Blankson, Joel N, Smith, Kellie N

“…BACKGROUNDRecent studies have reported T cell immunity to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in unexposed donors, possibly due to…”
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Impact of Checkpoint Inhibitor Pneumonitis on Survival in NSCLC Patients Receiving Immune Checkpoint Immunotherapy by Suresh, Karthik, Psoter, Kevin J, Voong, Khinh Ranh, Shankar, Bairavi, Forde, Patrick M, Ettinger, David S, Marrone, Kristen A, Kelly, Ronan J, Hann, Christine L, Levy, Benjamin, Feliciano, Josephine L, Brahmer, Julie R, Feller-Kopman, David, Lerner, Andrew D, Lee, Hans, Yarmus, Lonny, Hales, Russell K, D'Alessio, Franco, Danoff, Sonye K, Naidoo, Jarushka

“…With increasing use of immune checkpoint inhibitors (ICIs) for advanced NSCLC, there is increasing recognition of immune-related adverse events associated with…”
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HIV Impairs Lung Epithelial Integrity and Enters the Epithelium to Promote Chronic Lung Inflammation by Brune, Kieran A, Ferreira, Fernanda, Mandke, Pooja, Chau, Eric, Aggarwal, Neil R, D'Alessio, Franco R, Lambert, Allison A, Kirk, Gregory, Blankson, Joel, Drummond, M Bradley, Tsibris, Athe M, Sidhaye, Venkataramana K

“…Several clinical studies show that individuals with HIV are at an increased risk for worsened lung function and for the development of COPD, although the…”
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Sulforaphane exhibits antiviral activity against pandemic SARS-CoV-2 and seasonal HCoV-OC43 coronaviruses in vitro and in mice by Ordonez, Alvaro A., Bullen, C. Korin, Villabona-Rueda, Andres F., Thompson, Elizabeth A., Turner, Mitchell L., Merino, Vanessa F., Yan, Yu, Kim, John, Davis, Stephanie L., Komm, Oliver, Powell, Jonathan D., D’Alessio, Franco R., Yolken, Robert H., Jain, Sanjay K., Jones-Brando, Lorraine

“…Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the cause of coronavirus disease 2019 (COVID-19), has incited a global health crisis. Currently,…”
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An adapted anti-CTLA4 therapeutic aimed at mitigating the toxicities of checkpoint inhibition by Naidoo, Jarushka, Dykema, Arbor, D'Alessio, Franco

“…Antibodies that target immune checkpoint molecules, such as CTLA4, provide robust antitumor effects in a subset of patients. Unfortunately, not all patients…”
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Regulatory T cells reduce acute lung injury fibroproliferation by decreasing fibrocyte recruitment by Garibaldi, Brian T, D'Alessio, Franco R, Mock, Jason R, Files, D Clark, Chau, Eric, Eto, Yoshiki, Drummond, M Bradley, Aggarwal, Neil R, Sidhaye, Venkataramana, King, Landon S

“…Acute lung injury (ALI) causes significant morbidity and mortality. Fibroproliferation in ALI results in worse outcomes, but the mechanisms governing…”
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