Search Results - "Francisco Barajas-Olmos"

CFTR pathogenic variants spectrum in a cohort of Mexican patients with cystic fibrosis by Martínez-Hernández, Angélica, Mendoza-Caamal, Elvia C., Mendiola-Vidal, Namibia G., Barajas-Olmos, Francisco, Villafan-Bernal, José Rafael, Jiménez-Ruiz, Juan Luis, Monge-Cazares, Tulia, García-Ortiz, Humberto, Cubas, Cecilia Contreras, Centeno-Cruz, Federico, Alaez-Verson, Carmen, Ortega-Torres, Soraya, Luna-Castañeda, Adriana del C., Baca, Vicente, Lezana, José Luis, Orozco, Lorena

“…Molecular diagnosis of cystic fibrosis (CF) is challenging in Mexico due to the population's high genetic heterogeneity. To date, 46 pathogenic variants (PVs)…”
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Reconstruction of ancient microbial genomes from the human gut by Wibowo, Marsha C., Yang, Zhen, Borry, Maxime, Hübner, Alexander, Huang, Kun D., Tierney, Braden T., Zimmerman, Samuel, Barajas-Olmos, Francisco, Contreras-Cubas, Cecilia, García-Ortiz, Humberto, Martínez-Hernández, Angélica, Luber, Jacob M., Kirstahler, Philipp, Blohm, Tre, Smiley, Francis E., Arnold, Richard, Ballal, Sonia A., Pamp, Sünje Johanna, Russ, Julia, Maixner, Frank, Rota-Stabelli, Omar, Segata, Nicola, Reinhard, Karl, Orozco, Lorena, Warinner, Christina, Snow, Meradeth, LeBlanc, Steven, Kostic, Aleksandar D.

“…Loss of gut microbial diversity 1 – 6 in industrial populations is associated with chronic diseases 7 , underscoring the importance of studying our ancestral…”
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The genomic landscape of Mexican Indigenous populations brings insights into the peopling of the Americas by García-Ortiz, Humberto, Barajas-Olmos, Francisco, Contreras-Cubas, Cecilia, Cid-Soto, Miguel Ángel, Córdova, Emilio J., Centeno-Cruz, Federico, Mendoza-Caamal, Elvia, Cicerón-Arellano, Isabel, Flores-Huacuja, Marlen, Baca, Paulina, Bolnick, Deborah A., Snow, Meradeth, Flores-Martínez, Silvia Esperanza, Ortiz-Lopez, Rocio, Reynolds, Austin W., Blanchet, Antonio, Morales-Marín, Mirna, Velázquez-Cruz, Rafael, Kostic, Aleksandar David, Galaviz-Hernández, Carlos, García-Zapién, Alejandra Guadalupe, Jiménez-López, José Concepción, León-Reyes, Guadalupe, Salas-Bautista, Eva Gabriela, Lazalde-Ramos, Blanca Patricia, Jiménez-Ruíz, Juan Luis, Salas-Martínez, Guadalupe, Ramos-Madrigal, Jazmín, Mirzaeicheshmeh, Elaheh, Saldaña-Alvarez, Yolanda, del Carmen Abrahantes-Pérez, María, Loeza-Becerra, Francisco, Mojica-Espinosa, Raúl, Sánchez-Quinto, Federico, Rangel-Villalobos, Héctor, Sosa-Macías, Martha, Sánchez-Corona, José, Rojas-Martinez, Augusto, Martínez-Hernández, Angélica, Orozco, Lorena

“…The genetic makeup of Indigenous populations inhabiting Mexico has been strongly influenced by geography and demographic history. Here, we perform a…”
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Kazak mitochondrial genomes provide insights into the human population history of Central Eurasia by Ayken Askapuli, Miguel Vilar, Humberto Garcia-Ortiz, Maxat Zhabagin, Zhaxylyk Sabitov, Ainur Akilzhanova, Erlan Ramanculov, Uli Schamiloglu, Angelica Martinez-Hernandez, Cecilia Contreras-Cubas, Francisco Barajas-Olmos, Theodore G Schurr, Zhaxybay Zhumadilov, Marlen Flores-Huacuja, Lorena Orozco, John Hawks, Naruya Saitou

“…As a historical nomadic group in Central Asia, Kazaks have mainly inhabited the steppe zone from the Altay Mountains in the East to the Caspian Sea in the…”
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Kazak mitochondrial genomes provide insights into the human population history of Central Eurasia by Askapuli, Ayken, Vilar, Miguel, Garcia-Ortiz, Humberto, Zhabagin, Maxat, Sabitov, Zhaxylyk, Akilzhanova, Ainur, Ramanculov, Erlan, Schamiloglu, Uli, Martinez-Hernandez, Angelica, Contreras-Cubas, Cecilia, Barajas-Olmos, Francisco, Schurr, Theodore G, Zhumadilov, Zhaxybay, Flores-Huacuja, Marlen, Orozco, Lorena, Hawks, John, Saitou, Naruya

“…As a historical nomadic group in Central Asia, Kazaks have mainly inhabited the steppe zone from the Altay Mountains in the East to the Caspian Sea in the…”
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Correction: Whole genome variation in 27 Mexican indigenous populations, demographic and biomedical insights by Aguilar-Ordoñez, Israel, Pérez-Villatoro, Fernando, García-Ortiz, Humberto, Barajas-Olmos, Francisco, Ballesteros-Villascán, Judith, Ram González-Buenfil, Fresno, Cristobal, Garcíarrubio, Alejandro, Fernández-López, Juan Carlos, Tovar, Hugo, Hernández-Lemus, Enrique, Orozco, Lorena, Soberón, Xavier, Morett, Enrique

“…[This corrects the article DOI: 10.1371/journal.pone.0249773.]…”
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Whole genome variation in 27 Mexican indigenous populations, demographic and biomedical insights by Aguilar-Ordoñez, Israel, Pérez-Villatoro, Fernando, García-Ortiz, Humberto, Barajas-Olmos, Francisco, Ballesteros-Villascán, Judith, González-Buenfil, Ram, Fresno, Cristobal, Garcíarrubio, Alejandro, Fernández-López, Juan Carlos, Tovar, Hugo, Hernández-Lemus, Enrique, Orozco, Lorena, Soberón, Xavier, Morett, Enrique

“…There has been limited study of Native American whole genome diversity to date, which impairs effective implementation of personalized medicine and a detailed…”
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Metabolic syndrome in indigenous communities in Mexico: a descriptive and cross-sectional study by Mendoza-Caamal, Elvia Cristina, Barajas-Olmos, Francisco, García-Ortiz, Humberto, Cicerón-Arellano, Isabel, Martínez-Hernández, Angélica, Córdova, Emilio J, Esparza-Aguilar, Marcelino, Contreras-Cubas, Cecilia, Centeno-Cruz, Federico, Cid-Soto, Miguel, Morales-Marín, Mirna Edith, Reséndiz-Rodríguez, Adriana, Jiménez-Ruiz, Juan Luis, Salas-Martínez, María Guadalupe, Saldaña-Alvarez, Yolanda, Mirzaeicheshmeh, Elaheh, Rojas-Martínez, María Rosalba, Orozco, Lorena

“…An Amerindian genetic background could play an important role in susceptibility to metabolic diseases, which have alarmingly increased in recent decades…”
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Analysis of the dynamic aberrant landscape of DNA methylation and gene expression during arsenic-induced cell transformation by Barajas-Olmos, Francisco M., Ortiz-Sánchez, Elizabeth, Imaz-Rosshandler, Ivan, Córdova-Alarcón, Emilio J., Martínez-Tovar, Adolfo, Villanueva-Toledo, Jairo, Morales-Marín, Mirna E., Cruz-Colín, José L., Rangel, Claudia, Orozco, Lorena, Centeno, Federico

“…Inorganic arsenic is a well-known carcinogen associated with several types of cancer, but the mechanisms involved in arsenic-induced carcinogenesis are not…”
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DNA methylation and gene expression analysis in adipose tissue to identify new loci associated with T2D development in obesity by Baca, Paulina, Barajas-Olmos, Francisco, Mirzaeicheshmeh, Elaheh, Zerrweck, Carlos, Guilbert, Lizbeth, Sánchez, Ernesto Carlos, Flores-Huacuja, Marlen, Villafán, Rafael, Martínez-Hernández, Angélica, García-Ortiz, Humberto, Contreras-Cubas, Cecilia, Centeno-Cruz, Federico, Orozco, Lorena

“…Background Obesity is accompanied by excess adipose fat storage, which may lead to adipose dysfunction, insulin resistance, and type 2 diabetes (T2D)…”
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Two novel variants in DYRK1B causative of AOMS3: expanding the clinical spectrum by Mendoza-Caamal, Elvia C, Barajas-Olmos, Francisco, Mirzaeicheshmeh, Elaheh, Ilizaliturri-Flores, Ian, Aguilar-Salinas, Carlos A, Gómez-Velasco, Donaji V, Cicerón-Arellano, Isabel, Reséndiz-Rodríguez, Adriana, Martínez-Hernández, Angélica, Contreras-Cubas, Cecilia, Islas-Andrade, Sergio, Zerrweck, Carlos, García-Ortiz, Humberto, Orozco, Lorena

“…We investigated pathogenic DYRK1B variants causative of abdominal obesity-metabolic syndrome 3 (AOMS3) in a group of patients originally diagnosed with type 2…”
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Altered DNA methylation in liver and adipose tissues derived from individuals with obesity and type 2 diabetes by Barajas-Olmos, Francisco, Centeno-Cruz, Federico, Zerrweck, Carlos, Imaz-Rosshandler, Iván, Martínez-Hernández, Angélica, Cordova, Emilio J, Rangel-Escareño, Claudia, Gálvez, Faustino, Castillo, Armando, Maydón, Hernán, Campos, Francisco, Maldonado-Pintado, Diana Gabriela, Orozco, Lorena

“…Obesity is a well-recognized risk factor for insulin resistance and type 2 diabetes (T2D), although the precise mechanisms underlying the relationship remain…”
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Heterogenous Distribution of MTHFR Gene Variants among Mestizos and Diverse Amerindian Groups from Mexico by Contreras-Cubas, Cecilia, Sánchez-Hernández, Beatríz E, García-Ortiz, Humberto, Martínez-Hernández, Angélica, Barajas-Olmos, Francisco, Cid, Miguel, Mendoza-Caamal, Elvia C, Centeno-Cruz, Federico, Ortiz-Cruz, Gabriela, Jiménez-López, José Concepción, Córdova, Emilio J, Salas-Bautista, Eva Gabriela, Saldaña-Alvarez, Yolanda, Fernández-López, Juan Carlos, Mutchinick, Osvaldo M, Orozco, Lorena

“…Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in folate metabolism. Folate deficiency has been related to several conditions, including neural…”
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Dysferlinopathy misdiagnosed with juvenile polymyositis in the pre-symptomatic stage of hyperCKemia: a case report and literature review by Contreras-Cubas, Cecilia, Barajas-Olmos, Francisco, Frayre-Martínez, Maria Inés, Siordia-Reyes, Georgina, Guízar-Sánchez, Claudia C, García-Ortiz, Humberto, Orozco, Lorena, Baca, Vicente

“…Dysferlinopathy encompasses a group of rare muscular dystrophies caused by recessive mutations in the DYSF gene. The phenotype ranges from asymptomatic…”
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DNA Methylation Remodeling after Bariatric Surgery Correlates with Clinical Parameters by Sánchez, Ernesto Carlos, Barajas-Olmos, Francisco, Baca, Paulina, Zerrweck, Carlos, Guilbert, Lizbeth, Martínez-Hernández, Angélica, Centeno, Federico, Orozco, Lorena

“…The altered functions of adipose tissue are one of the main issues in obesity. Bariatric surgery is associated with improvement of obesity associated…”
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Exome Sequence Data of Eight SLC Transporters Reveal That SLC22A1 and SLC22A3 Variants Alter Metformin Pharmacokinetics and Glycemic Control by Morales-Rivera, Monserrat I, Alemón-Medina, Radamés, Martínez-Hernández, Angélica, Contreras-Cubas, Cecilia, Altamirano-Bustamante, Nelly F, Gómez-Garduño, Josefina, Mendoza-Caamal, Elvia C, Nuñez-González, J Orlando, García-Álvarez, Raquel, Revilla-Monsalve, Cristina, Valcarcel-Gamiño, José Antonio, Villafan-Bernal, José Rafael, Centeno-Cruz, Federico, García-Ortiz, Humberto, Barajas-Olmos, Francisco, Orozco, Lorena

“…: Type 2 diabetes (T2D) is one of the leading causes of mortality and is a public health challenge worldwide. Metformin is the first-choice treatment for T2D;…”
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Genetic variability of five ADRB2 polymorphisms among Mexican Amerindian ethnicities and the Mestizo population by Salas-Martínez, María Guadalupe, Saldaña-Alvarez, Yolanda, Cordova, Emilio J, Mendiola-Soto, Diana Karen, Cid-Soto, Miguel A, Luckie-Duque, Angélica, Vicenteño-Ayala, Hermenegildo, Barajas-Olmos, Francisco, Contreras-Cubas, Cecilia, García-Ortiz, Humberto, Jiménez-Ruíz, Juan L, Centeno-Cruz, Federico, Martínez-Hernández, Angélica, Mendoza-Caamal, Elvia C, Mirzaeicheshmeh, Elaheh, Orozco, Lorena

“…The Mexican population is characterized by high and particular admixture, and the picture of variants associated with disease remains unclear. Here we…”
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The L125F MATE1 variant enriched in populations of Amerindian origin is associated with increased plasma levels of metformin and lactate by Morales-Rivera, Monserrat I., Alemón-Medina, Radamés, Martínez-Hernández, Angélica, Gómez-Garduño, Josefina, Mirzaeicheshmeh, Elaheh, Altamirano-Bustamante, Nelly F., Ilizaliturri-Flores, Ian, Mendoza-Caamal, Elvia C., Pérez-Guillé, María G., García-Álvarez, Raquel, Contreras-Cubas, Cecilia, Centeno-Cruz, Federico, Revilla-Monsalve, Cristina, García-Ortiz, Humberto, Barajas-Olmos, Francisco, Orozco, Lorena

“…Genetic factors that affect variability in metformin response have been poorly studied in the Latin American population, despite its being the initial drug…”
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Exome Sequencing Data Analysis and a Case-Control Study in Mexican Population Reveals Lipid Trait Associations of New and Known Genetic Variants in Dyslipidemia-Associated Loci by Jurado-Camacho, Pedro A, Cid-Soto, Miguel A, Barajas-Olmos, Francisco, García-Ortíz, Humberto, Baca-Peynado, Paulina, Martínez-Hernández, Angélica, Centeno-Cruz, Federico, Contreras-Cubas, Cecilia, González-Villalpando, María Elena, Saldaña-Álvarez, Yolanda, Salas-Martinez, Guadalupe, Mendoza-Caamal, Elvia C, González-Villalpando, Clicerio, Córdova, Emilio J, Orozco, Lorena

“…Plasma lipid levels are a major risk factor for cardiovascular diseases. Although international efforts have identified a group of loci associated with the…”
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Variation in Actionable Pharmacogenetic Markers in Natives and Mestizos From Mexico by Gonzalez-Covarrubias, Vanessa, Morales-Franco, Marlet, Cruz-Correa, Omar F., Martínez-Hernández, Angélica, García-Ortíz, Humberto, Barajas-Olmos, Francisco, Genis-Mendoza, Alma Delia, Martínez-Magaña, José Jaime, Nicolini, Humberto, Orozco, Lorena, Soberón, Xavier

“…The identification and characterization of pharmacogenetic variants in Latin American populations is still an ongoing endeavor. Here, we investigated SNVs on…”
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