Search Results - "Francisco, Sarah G."

Dietary Patterns, Carbohydrates, and Age-Related Eye Diseases by Francisco, Sarah G, Smith, Kelsey M, Aragonès, Gemma, Whitcomb, Elizabeth A, Weinberg, Jasper, Wang, Xuedi, Bejarano, Eloy, Taylor, Allen, Rowan, Sheldon

“…Over a third of older adults in the U.S. experience significant vision loss, which decreases independence and is a biomarker of decreased health span. As the…”
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Glyoxalase System as a Therapeutic Target against Diabetic Retinopathy by Aragonès, Gemma, Rowan, Sheldon, G Francisco, Sarah, Yang, Wenxin, Weinberg, Jasper, Taylor, Allen, Bejarano, Eloy

“…Hyperglycemia, a defining characteristic of diabetes, combined with oxidative stress, results in the formation of advanced glycation end products (AGEs). AGEs…”
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Autophagic receptor p62 protects against glycation‐derived toxicity and enhances viability by Aragonès, Gemma, Dasuri, Kalavathi, Olukorede, Opeoluwa, Francisco, Sarah G., Renneburg, Carol, Kumsta, Caroline, Hansen, Malene, Kageyama, Shun, Komatsu, Masaaki, Rowan, Sheldon, Volkin, Jonathan, Workman, Michael, Yang, Wenxin, Daza, Paula, Ruano, Diego, Dominguez‐Martín, Helena, Rodríguez‐Navarro, José Antonio, Du, Xue‐Liang, Brownlee, Michael A., Bejarano, Eloy, Taylor, Allen

“…Diabetes and metabolic syndrome are associated with the typical American high glycemia diet and result in accumulation of high levels of advanced glycation end…”
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Aged Nrf2-Null Mice Develop All Major Types of Age-Related Cataracts by Rowan, Sheldon, Jiang, Shuhong, Francisco, Sarah G, Pomatto, Laura C D, Ma, Zhiwei, Jiao, Xiaodong, Campos, Maria M, Aryal, Sandeep, Patel, Shaili D, Mahaling, Binapani, Riazuddin, S Amer, Duh, Elia J, Lachke, Salil A, Hejtmancik, J Fielding, de Cabo, Rafael, FitzGerald, Paul G, Taylor, Allen

“…Age-related cataracts affect the majority of older adults and are a leading cause of blindness worldwide. Treatments that delay cataract onset or severity have…”
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The Glyoxalase System in Age-Related Diseases: Nutritional Intervention as Anti-Ageing Strategy by Aragonès, Gemma, Rowan, Sheldon, Francisco, Sarah G., Whitcomb, Elizabeth A., Yang, Wenxin, Perini-Villanueva, Giuliana, Schalkwijk, Casper G., Taylor, Allen, Bejarano, Eloy

“…The glyoxalase system is critical for the detoxification of advanced glycation end-products (AGEs). AGEs are toxic compounds resulting from the non-enzymatic…”
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Selective transcriptomic dysregulation of metabolic pathways in liver and retina by short- and long-term dietary hyperglycemia by Mondal, Anupam K., Brock, Daniel C., Rowan, Sheldon, Yang, Zhi-Hong, Rojulpote, Krishna Vamsi, Smith, Kelsey M., Francisco, Sarah G., Bejarano, Eloy, English, Milton A., Deik, Amy, Jeanfavre, Sarah, Clish, Clary B., Remaley, Alan T., Taylor, Allen, Swaroop, Anand

“…A high glycemic index (HGI) diet induces hyperglycemia, a risk factor for diseases affecting multiple organ systems. Here, we evaluated tissue-specific…”
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Repurposing Drugs for Treatment of Age-Related Macular Degeneration by Francisco, Sarah G, Rowan, Sheldon

“…The need for new drugs to treat dry forms of age-related macular degeneration remains high. A promising approach is repurposing of FDA-approved medications to…”
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Preservation of Olfactory Function After Pediatric Endoscopic Endonasal Skull Base Surgery with Nasoseptal Flap Reconstruction by Baird, Lissa, Francisco, Sarah G., Auyeung, Tammy, Adil, Eelam

“…Endoscopic endonasal surgery is a feasible approach to lesions of the pediatric skull base. Olfactory outcomes after endoscopic endonasal approach (EEA) have…”
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Preservation of olfactory function following pediatric endoscopic endonasal skull base surgery with nasoseptal flap reconstruction by Baird, Lissa, Francisco, Sarah G, Auyeung, Tammy, Adil, Eelam

“…Endoscopic endonasal surgery is a feasible approach to lesions of the pediatric skull base. Olfactory outcomes following endoscopic endonasal approach (EEA)…”
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A reciprocal translocation involving Aspergillus nidulans snxAHrb1/Gbp2 and gyfA uncovers a new regulator of the G2–M transition and reveals a role in transcriptional repression for the setBSet2 histone H3-lysine-36 methyltransferase by James, Steven W, Palmer, Jonathan, Keller, Nancy P, Brown, Morgan L, Dunworth, Matthew R, Francisco, Sarah G, Watson, Katherine G, Titchen, Breanna, Achimovich, Alecia, Mahoney, Andrew, Artemiou, Joseph P, Buettner, Kyra G, Class, Madelyn, Sydenstricker, Andrew L, Anglin, Sarah Lea

“…Abstract Aspergillus nidulans snxA, an ortholog of Saccharomyces cerevisiae Hrb1/Gbp2 messenger RNA shuttle proteins, is—in contrast to budding yeast—involved…”
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A reciprocal translocation involving Aspergillus nidulans snxA Hrb1/Gbp2 and gyfA uncovers a new regulator of the G2–M transition and reveals a role in transcriptional repression for the setB Set2 histone H3-lysine-36 methyltransferase by James, Steven W, Palmer, Jonathan, Keller, Nancy P, Brown, Morgan L, Dunworth, Matthew R, Francisco, Sarah G, Watson, Katherine G, Titchen, Breanna, Achimovich, Alecia, Mahoney, Andrew, Artemiou, Joseph P, Buettner, Kyra G, Class, Madelyn, Sydenstricker, Andrew L, Anglin, Sarah Lea

“…Aspergillus nidulans snxA, an ortholog of Saccharomyces cerevisiae Hrb1/Gbp2 messenger RNA shuttle proteins, is—in contrast to budding yeast—involved in cell…”
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