Search Results - "Francisco, Jamie"

Inflammation in Myocardial Ischemia/Reperfusion Injury: Underlying Mechanisms and Therapeutic Potential by Francisco, Jamie, Del Re, Dominic P

“…Acute myocardial infarction (MI) occurs when blood flow to the myocardium is restricted, leading to cardiac damage and massive loss of viable cardiomyocytes…”
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Decoding the Impact of the Hippo Pathway on Different Cell Types in Heart Failure by Hu, Chengchen, Francisco, Jamie, Re, Dominic P. Del, Sadoshima, Junichi

“…The evolutionarily conserved Hippo pathway plays a pivotal role in governing a variety of biological processes. Heart failure (HF) is a major global health…”
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Suppression of myeloid YAP antagonizes adverse cardiac remodeling during pressure overload stress by Francisco, Jamie, Guan, Jin, Zhang, Yu, Nakada, Yasuki, Mareedu, Satvik, Sung, Eun-Ah, Hu, Che-Ming, Oka, Shinichi, Zhai, Peiyong, Sadoshima, Junichi, Del Re, Dominic P.

“…Inflammation is an integral component of cardiovascular disease and is thought to contribute to cardiac dysfunction and heart failure. While ischemia-induced…”
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AAV-mediated YAP expression in cardiac fibroblasts promotes inflammation and increases fibrosis by Francisco, Jamie, Zhang, Yu, Nakada, Yasuki, Jeong, Jae Im, Huang, Chun-Yang, Ivessa, Andreas, Oka, Shinichi, Babu, Gopal J., Del Re, Dominic P.

“…Fibrosis is a hallmark of heart disease independent of etiology and is thought to contribute to impaired cardiac dysfunction and development of heart failure…”
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Blockade of Fibroblast YAP Attenuates Cardiac Fibrosis and Dysfunction Through MRTF-A Inhibition by Francisco, Jamie, Zhang, Yu, Jeong, Jae Im, Mizushima, Wataru, Ikeda, Shohei, Ivessa, Andreas, Oka, Shinichi, Zhai, Peiyong, Tallquist, Michelle D., Del Re, Dominic P.

“…[Display omitted] •YAP is activated by myocardial infarction or neuroendocrine stimulation in cardiac fibroblasts.•Active YAP promotes TEA domain transcription…”
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Thioredoxin 1 promotes autophagy through transnitrosylation of Atg7 during myocardial ischemia by Nagarajan, Narayani, Oka, Shin-Ichi, Nah, Jihoon, Wu, Changgong, Zhai, Peiyong, Mukai, Risa, Xu, Xiaoyong, Kashyap, Sanchita, Huang, Chun-Yang, Sung, Eun-Ah, Mizushima, Wataru, Titus, Allen Sam, Takayama, Koichiro, Mourad, Youssef, Francisco, Jamie, Liu, Tong, Chen, Tong, Li, Hong, Sadoshima, Junichi

“…Modification of cysteine residues by oxidative and nitrosative stress affects structure and function of proteins, thereby contributing to the pathogenesis of…”
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Novel Antifungal Drug Discovery Based on Targeting Pathways Regulating the Fungus-Conserved Upc2 Transcription Factor by GALLO-EBERT, Christina, DONIGAN, Melissa, WEBB, Maria, NICKELS, Joseph T, STROKE, Ilana L, SWANSON, Robert N, MANNERS, Melissa T, FRANCISCO, Jamie, TONER, Geoffrey, GALLAGHER, Denise, HUANG, Chia-Yu, GYGAX, Scott E

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Inhibition of AMP Kinase by the Protein Phosphatase 2A Heterotrimer, PP2APpp2r2d by Joseph, Biny K., Liu, Hsing-Yin, Francisco, Jamie, Pandya, Devanshi, Donigan, Melissa, Gallo-Ebert, Christina, Giordano, Caroline, Bata, Adam, Nickels, Joseph T.

“…AMP kinase is a heterotrimeric serine/threonine protein kinase that regulates a number of metabolic processes, including lipid biosynthesis and metabolism. AMP…”
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Mice lacking have reduced signs of metabolic syndrome and non-alcoholic fatty liver disease by Gallo-Ebert, Christina, Francisco, Jamie, Liu, Hsing-Yin, Draper, Riley, Modi, Kinnari, Hayward, Michael D., Jones, Beverly K., Buiakova, Olesia, McDonough, Virginia, Nickels, Joseph T.

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Abstract P3091: Suppression Of Myeloid Yap Antagonizes Adverse Cardiac Remodeling During Pressure Overload Stress by Francisco, Jamie, Del Re, Dominic

“…Abstract only Inflammation is an integral component of cardiovascular disease and is thought to contribute to cardiac dysfunction and heart failure. While…”
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Abstract Mo137: Modulation of the Inflammatory and Fibrotic Effects of Angiotensin on Cardiomyocytes through YAP-mediated Transcription by Ninh, Van, Brand, Cameron, Barlow, Melissa, Aydin, Sidar, Francisco, Jamie, Del Re, Dominic, Heller Brown, Joan

“…Abstract only Introduction: Signaling through the transcriptional co-activator Yes-associated protein (YAP) has been shown to protect the myocardium against…”
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Abstract We070: The role of neutrophil YAP in cardiac inflammation and injury by Francisco, Jamie, Mareedu, Satvik, Guan, Jin, Sung, Eun-Ah, Zhai, Peiyong, Hu, Che-Ming, Del Re, Dominic

“…Abstract only Background: There is a growing appreciation that neutrophils demonstrate plasticity, not unlike the macrophage, and can modulate both…”
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Abstract P480: Myeloid YAP Inhibition Improves Cardiac Phenotype During Pressure Overload Stress by Francisco, Jamie J, Zhang, Yu, Nakada, Yasuki, Zhai, Peiyong, Del Re, Dominic

“…Inflammation is a component of cardiovascular disease and is thought to contribute to cardiac dysfunction in ischemic and non-ischemic models of heart failure…”
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Abstract Tu116: Neurofibromin 2 regulates metabolic gene expression and cardiac responses to pressure overload stress by Zhang, Yu, Mareedu, Satvik, Mizushima, Wataru, Francisco, Jamie, Guan, Jin, Yang, Zhi, Oka, Shinichi, Zhai, Peiyong, Abdellatif, Maha, Sadoshima, Junichi, Del Re, Dominic

“…Abstract only Background: Neurofibromin 2 (NF2) is a tumor suppressor that can engage multiple signaling pathways to modulate cell proliferation and survival…”
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Abstract P3065: Myeloid YAP Inhibition Improves Cardiac Phenotype During Pressure Overload Stress by Francisco, Jamie J, Zhang, Yu, Nakada, Yasuki, Hu, Che-Ming, Oka, Shinichi, Zhai, Peiyong, Del Re, Dominic

“…Inflammation is an integral component of cardiovascular disease and is thought to contribute to cardiac dysfunction in ischemic and non-ischemic models of…”
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Abstract P2057: The Role Of Cardiac Neurofibromin-2 In Chronic Pressure Overload by Mareedu, Satvik, Zhang, Yu, Mizushima, Wataru, Francisco, Jamie, Guan, Jin, Yang, Zhi, Oka, Shinichi, Zhai, Peiyong, Abdellatif, Maha, Del Re, Dominic

“…Abstract only Department of Cell Biology and Molecular Medicine, New Jersey Medical School, Rutgers University, Newark, NJ 07103.Neurofibromin 2 (NF2) is a…”
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Injectable Peptide Hydrogels Loaded with Murine Embryonic Stem Cells Relieve Ischemia In Vivo after Myocardial Infarction by Roy, Abhishek, Hao, Lei, Francisco, Jamie, Guan, Jin, Mareedu, Satvik, Zhai, Peiyong, Dodd-o, Joseph, Heffernan, Corey, Del Re, Dominic, Lee, Eun Jung A., Kumar, Vivek A.

“…Myocardial infarction (MI) is a major cause of morbidity and mortality worldwide, especially in aging and metabolically unhealthy populations. A major target…”
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Myeloid YAP Inhibition Improves Cardiac Phenotype During Pressure Overload Stress by Francisco, Jamie, Zhang, Yu, Nakada, Yasuki, Hu, Che‐Ming, Zhai, Peiyong, Del Re, Dominic P.

“…Inflammation is an integral component of cardiovascular disease and is thought to contribute to cardiac dysfunction in ischemic and non‐ischemic models of…”
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The tumor suppressor RASSF1A modulates inflammation and injury in the reperfused murine myocardium by Francisco, Jamie, Byun, Jaemin, Zhang, Yu, Kalloo, Olivia Berman, Mizushima, Wataru, Oka, Shinichi, Zhai, Peiyong, Sadoshima, Junichi, Del Re, Dominic P.

“…Inflammation is a central feature of cardiovascular disease, including myocardial infarction and heart failure. Reperfusion of the ischemic myocardium triggers…”
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Mice lacking ARV1 have reduced signs of metabolic syndrome and non-alcoholic fatty liver disease by Gallo-Ebert, Christina, Francisco, Jamie, Liu, Hsing-Yin, Draper, Riley, Modi, Kinnari, Hayward, Michael D., Jones, Beverly K., Buiakova, Olesia, McDonough, Virginia, Nickels, Joseph T.

“…Metabolic syndrome (MetS) is a term used to characterize individuals having at least three of the following diseases: obesity, dyslipidemia, hyperglycemia,…”
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