Search Results - "Francisco, J.M."
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On the Origin of CRISPR-Cas Technology: From Prokaryotes to Mammals
Published in Trends in microbiology (Regular ed.) (01-10-2016)“…Clustered regularly-interspaced short palindromic repeat (CRISPR) sequences cooperate with CRISPR-associated (Cas) proteins to form the basis of CRISPR-Cas…”
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An updated evolutionary classification of CRISPR–Cas systems
Published in Nature reviews. Microbiology (01-11-2015)“…Key Points CRISPR–Cas systems provide archaea and bacteria with adaptive immunity against viruses and plasmids. CRISPR–Cas genomic loci show extreme diversity…”
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Evolution and classification of the CRISPR–Cas systems
Published in Nature reviews. Microbiology (01-06-2011)“…The CRISPR–Cas (clustered regularly interspaced short palindromic repeats–CRISPR-associated proteins) systems are immunity systems that are present in many…”
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Intervening sequences of regularly spaced prokaryotic repeats derive from foreign genetic elements
Published in Journal of molecular evolution (01-02-2005)“…Prokaryotes contain short DN repeats known as CRISPR, recognizable by the regular spacing existing between the recurring units. They represent the most widely…”
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The Hazardous Level of Heavy Metals in Different Medicinal Plants and Their Decoctions in Water: A Public Health Problem in Brazil
Published in BioMed research international (2020)“…The determination of Cd, Co, Cr, Cu, Fe, Na, Zn, and Pb by inductively coupled plasma-optical emission spectrometry (ICP OES) was performed on dry matter and…”
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Right of admission reserved, no matter the path
Published in Trends in microbiology (Regular ed.) (01-09-2013)“…Native CRISPR-Cas adaptive immunity systems prevent plasmid conjugation and virus-mediated gene transfer. Zhang et al . have recently reported in Molecular…”
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Shear velocity criterion for incipient motion of sediment
Published in Water Science and Engineering (01-04-2014)“…The prediction of incipient motion has had great importance to the theory of sediment transport. The most commonly used methods are based on the concept of…”
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Blood transfusion reactions in children: associated factors
Published in Jornal de pediatria (01-07-2013)“…To analyze the profile of blood transfusion reactions in children and to identify the involved factors. This was a cross-sectional study in a tertiary…”
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Fragomented Health Care Delivery in Ichthyosis
Published in Actas dermo-sifiliográficas (English ed.) (01-07-2015)Get full text
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Exploring Forces between Individual Colloidal Particles with the Atomic Force Microscope
Published in Chimia (01-01-2012)“…Forces between individual colloidal particles can be measured with the atomic force microscope (AFM), and this technique permits the study of interactions…”
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Blood transfusion reactions in children: Associated factors
Published in Jornal de Pediatria (Versão em Português) (01-07-2013)“…To analyze the profile of blood transfusion reactions in children and to identify the involved factors. This was a cross-sectional study in a tertiary…”
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GSTARS computer models and their applications, part I: theoretical development
Published in International journal of sediment research (01-09-2008)“…GSTARS is a series of computer models developed by the U.S. Bureau of Reclamation for alluvial river and reservoir sedimentation studies while the authors were…”
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Evolutionary classification of CRISPR–Cas systems: a burst of class 2 and derived variants
Published in Nature reviews. Microbiology (01-02-2020)“…The number and diversity of known CRISPR–Cas systems have substantially increased in recent years. Here, we provide an updated evolutionary classification of…”
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14
The discovery of CRISPR in archaea and bacteria
Published in The FEBS journal (01-09-2016)“…CRISPR‐Cas are self‐/nonself‐discriminating systems found in prokaryotic cells. They represent a remarkable example of molecular memory that is hereditarily…”
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Protospacer recognition motifs: Mixed identities and functional diversity
Published in RNA biology (01-05-2013)“…Protospacer adjacent motifs (PAMs) were originally characterized for CRISPR-Cas systems that were classified on the basis of their CRISPR repeat sequences. A…”
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Thermomechanical characterization of Alclad AA2024-T3 aluminum alloy using split Hopkinson tension bar
Published in Mechanics of materials (01-12-2019)“…This work covers the mechanical behavior of Alclad AA2024-T3 aluminum alloy subjected to strain rates ranging from 10−3 s−1 to 1150 s−1 and temperatures from…”
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Impact of concurrent treatment with omeprazole on phenylbutazone‐induced equine gastric ulcer syndrome (EGUS)
Published in Equine veterinary journal (01-03-2021)“…Background Phenylbutazone is commonly prescribed for treatment of various painful or inflammatory disorders in horses, but is associated with gastrointestinal…”
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[Translated article] Improvements in the Management of Patients With Generalized Pustular Psoriasis in Spain: Recommendations From a Group of Experts
Published in Actas dermo-sifiliográficas (01-09-2024)“…This consensus document analyzed the management and emotional journey of patients with GPP (generalized pustular psoriasis), and the desirable course of the…”
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Digging into the lesser-known aspects of CRISPR biology
Published in International microbiology (01-11-2021)“…A long time has passed since regularly interspaced DNA repeats were discovered in prokaryotes. Today, those enigmatic repetitive elements termed clustered…”
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CRISPR-spacer integration reporter plasmids reveal distinct genuine acquisition specificities among CRISPR-Cas I-E variants of Escherichia coli
Published in RNA biology (01-05-2013)“…Prokaryotes immunize themselves against transmissible genetic elements by the integration (acquisition) in clustered regularly interspaced short palindromic…”
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