Search Results - "Francisco, Flávio Andrade"
-
1
Maternal diet-induced obesity during suckling period programs offspring obese phenotype and hypothalamic leptin/insulin resistance
Published in The Journal of nutritional biochemistry (01-11-2018)“…During the early post-natal period, offspring are vulnerable to environmental insults, such as nutritional and hormonal changes, which increase risk to develop…”
Get full text
Journal Article -
2
Early metformin treatment improves pancreatic function and prevents metabolic dysfunction in early overfeeding male rats at adulthood
Published in Experimental physiology (01-12-2020)“…New Findings What is the central question of this study? Studies reported the efficacy of metformin as a promising drug for preventing or treating of metabolic…”
Get full text
Journal Article -
3
Particulate Matter Exposure During Perinatal Life Results in Impaired Glucose Metabolism in Adult Male Rat Offspring
Published in Cellular physiology and biochemistry (01-01-2018)“…Background/Aims: Particulate matter (PM) is an important risk factor for immunological system imbalance due to its small size, which can reach more distal…”
Get full text
Journal Article -
4
Methylglyoxal treatment in lactating mothers leads to type 2 diabetes phenotype in male rat offspring at adulthood
Published in European journal of nutrition (01-03-2018)“…Purpose Environmental and nutritional disorders during perinatal period cause metabolic dysfunction in the progeny and impair human health. Advanced glycation…”
Get full text
Journal Article -
5
Puberty as a DOHaD programming window: high-fat diet induces long-term hepatic dysfunction in male rats
Published in Journal of developmental origins of health and disease (01-10-2023)“…The aim of this study was to evaluate whether high-fat (HF) diet intake during puberty can program obesity as well as generate glucose imbalance and hepatic…”
Get more information
Journal Article -
6
Soy isoflavones recover pancreatic islet function and prevent metabolic dysfunction in male rats
Published in Journal of endocrinology (07-07-2021)“…We tested whether chronic supplementation with soy isoflavones could modulate insulin secretion levels and subsequent recovery of pancreatic islet function as…”
Get full text
Journal Article -
7
Postnatal early overfeeding induces cardiovascular dysfunction by oxidative stress in adult male Wistar rats
Published in Life sciences (1973) (01-06-2019)“…Obesity is associated with innumerous comorbidities, including cardiovascular diseases, that occur by various mechanisms, including hyperactivation of the…”
Get full text
Journal Article -
8
Acephate exposure during a perinatal life program to type 2 diabetes
Published in Toxicology (Amsterdam) (30-11-2016)“…Abstract Acephate has been used extensively as an insecticide in agriculture. Its downstream sequelae are associated with hyperglycemia, lipid metabolism…”
Get full text
Journal Article -
9
Protein-restriction diet during the suckling phase programs rat metabolism against obesity and insulin resistance exacerbation induced by a high-fat diet in adulthood
Published in The Journal of nutritional biochemistry (01-07-2018)“…Protein restriction during the suckling phase can malprogram rat offspring to a lean phenotype associated with metabolic dysfunctions later in life. We tested…”
Get full text
Journal Article -
10
Strength training reverses ovariectomy-induced bone loss and improve metabolic parameters in female Wistar rats
Published in Life sciences (1973) (15-11-2018)“…Menopause induces osteoporosis, sarcopenia, insulin resistance, and dyslipidemia. Ovariectomized (OVX) rat is an animal model, which mimetics postmenopausal…”
Get full text
Journal Article -
11
Potential attenuation of early-life overfeeding-induced metabolic dysfunction by chronic maternal acetylcholinesterase inhibitor exposure
Published in Toxicology (Amsterdam) (01-09-2019)“…AbstractEvidence suggests that low concentration perinatal exposure to environmental contaminants, such as organophosphate (OP) is associated with later life…”
Get full text
Journal Article -
12
Forced internal desynchrony induces cardiometabolic alterations in adult rats
Published in Journal of endocrinology (01-08-2019)“…Disruptions in circadian rhythms have been associated with several diseases, including cardiovascular and metabolic disorders. Forced internal…”
Get full text
Journal Article -
13
Maternal low intensity physical exercise prevents obesity in offspring rats exposed to early overnutrition
Published in Scientific reports (09-08-2017)“…Low intensity exercise during pregnancy and lactation may create a protective effect against the development of obesity in offspring exposed to overnutrition…”
Get full text
Journal Article -
14
Treatment with soy isoflavones during early adulthood improves metabolism in early postnatally overfed rats
Published in Nutritional neuroscience (02-01-2018)“…Purpose: The incidences of obesity and related diseases have reached epidemic proportions, and new therapeutic approaches are needed. Soy isoflavones have been…”
Get full text
Journal Article -
15
Metformin Improves Autonomic Nervous System Imbalance and Metabolic Dysfunction in Monosodium L-Glutamate-Treated Rats
Published in Frontiers in endocrinology (Lausanne) (04-06-2021)“…Metformin is an antidiabetic drug used for the treatment of diabetes and metabolic diseases. Imbalance in the autonomic nervous system (ANS) is associated with…”
Get full text
Journal Article -
16
Anti-Diabetic Effects of the Ethyl-Acetate Fraction of Trichilia catigua in Streptozo-tocin-Induced Type 1 Diabetic Rats
Published in Cellular physiology and biochemistry (01-01-2017)“…Background/Aims: Trichilia catigua A. Juss., known as “catuaba” in Brazil, has been popularly used as a tonic for fatigue, impotence and memory deficits…”
Get full text
Journal Article -
17
Fecal Microbiota Transplantation During Lactation Programs the Metabolism of Adult Wistar Rats in a Sex-specific Way
Published in Archives of medical research (01-07-2022)“…BACKGROUNDThe intestinal microbiota is involved in many physiological processes. However, the effects of microbiota in metabolic programming still unknow. We…”
Get full text
Journal Article -
18
Neonatal treatment with scopolamine butylbromide prevents metabolic dysfunction in male rats
Published in Scientific reports (26-08-2016)“…We tested whether treatment with a cholinergic antagonist could reduce insulin levels in early postnatal life and attenuate metabolic dysfunctions induced by…”
Get full text
Journal Article -
19
Moderate exercise training since adolescence reduces Walker 256 tumour growth in adult rats
Published in The Journal of physiology (01-08-2019)“…Key points Cancer growth, cell proliferation and cachexia index can be attenuated by the beneficial programming effect of moderate exercise training,…”
Get full text
Journal Article -
20
Chronic Glibenclamide Treatment Attenuates Walker-256 Tumour Growth in Prediabetic Obese Rats
Published in Cellular physiology and biochemistry (01-01-2017)“…Background/Aims: The sulphonylurea glibenclamide (Gli) is widely used in the treatment of type 2 diabetes. In addition to its antidiabetic effects, low…”
Get full text
Journal Article