Search Results - "Francisco, E. Brian"

Mechanisms of resistance to cabazitaxel by Duran, George E, Wang, Yan C, Francisco, E Brian, Rose, John C, Martinez, Francisco J, Coller, John, Brassard, Diana, Vrignaud, Patricia, Sikic, Branimir I

“…We studied mechanisms of resistance to the novel taxane cabazitaxel in established cellular models of taxane resistance. We also developed…”
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The miR-200 family differentially regulates sensitivity to paclitaxel and carboplatin in human ovarian carcinoma OVCAR-3 and MES-OV cells by Brozovic, Anamaria, Duran, George E., Wang, Yan C., Francisco, E. Brian, Sikic, Branimir I.

“…We studied the role of miRNA-200 family members in cellular sensitivity to paclitaxel and carboplatin, using two ovarian cancer cell lines, OVCAR-3 and MES-OV,…”
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Lithium-Ion Trapping from Local Structural Distortions in Sodium Super Ionic Conductor (NASICON) Electrolytes by Francisco, Brian E, Stoldt, Conrad R, M’Peko, Jean-Claude

“…Herein, we report a study on the structural and thermodynamic effects that cation size disparity may have in NASICON-type solid solutions. A sol–gel procedure…”
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Decreased levels of baseline and drug-induced tubulin polymerisation are hallmarks of resistance to taxanes in ovarian cancer cells and are associated with epithelial-to-mesenchymal transition by Duran, George E, Wang, Yan C, Moisan, François, Francisco, E Brian, Sikic, Branimir I

“…Background: ABCB1 expression is uncommon in ovarian cancers in the clinical setting so we investigated non-MDR mechanisms of resistance to taxanes. Methods: We…”
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Combining Superionic Conduction and Favorable Decomposition Products in the Crystalline Lithium–Boron–Sulfur System: A New Mechanism for Stabilizing Solid Li-Ion Electrolytes by Sendek, Austin D, Antoniuk, Evan R, Cubuk, Ekin D, Ransom, Brandi, Francisco, Brian E, Buettner-Garrett, Josh, Cui, Yi, Reed, Evan J

“…We report a solid-state Li-ion electrolyte predicted to exhibit simultaneously fast ionic conductivity, wide electrochemical stability, low cost, and low mass…”
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Energetics of Ion Transport in NASICON-Type Electrolytes by Francisco, Brian E, Stoldt, Conrad R, M’Peko, Jean-Claude

“…Herein we report a study on the energetics of ion transport in NASICON-type solid electrolytes. A sol–gel procedure was used to synthesize NASICON-type…”
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Dual Polyanion Mechanism for Superionic Transport in BH 4 ‐Based Argyrodites by Wang, Pengbo, Liu, Haoyu, Patel, Sawankumar, Roberts, Jason E., Chen, Yudan, Ogbolu, Bright, Francisco, Brian E., Hu, Yan‐Yan

“…Abstract Polyanion rotations are often linked to cation diffusion, but the study of multiple polyanion systems is scarce due to the complexities in…”
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Abstract 763: Resistance to cabazitaxel is associated with ABCB1 /P-glycoprotein activation, alterations in β-tubulin content and dynamics, reduced BRCA1, and a mesenchymal phenotype in MCF-7 human breast cancer variants by Duran, George E., Wang, Yan C., Francisco, E Brian, Martinez, Francisco J., Sikic, Branimir I.

“…Abstract In order to identify determinants of cellular response to this new taxane, we derived a resistant variant from the MCF-7 human breast cancer cell line…”
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Abstract 901: Overexpression of inhibitors of apoptosis (IAP) family members in human breast and ovarian cancer models of non- MDR1 taxane resistance by Duran, George E., Brozovic, Anamaria, Martinez, Francisco J., Francisco, E Brian, Wang, Yan C., Sikic, Branimir I.

“…Abstract Four breast cancer cell lines (MCF-7, BT-549, MDA-MB-231 and T-47D) and four ovarian cancer cell lines (1A9/A2780, ES-2, MES-OV and OVCAR-3) were…”
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Abstract 1095: Comprehensive miRNA profiling of taxane-resistant human breast and ovarian cancer cell lines using the SmartChip real-time PCR system by Duran, George E., Wang, Cindy Y., Francisco, E. Brian, Wong, Kee, Robinson, Nicole, Sikic, Branimir I.

“…Abstract MiRNAs are post-transcriptional regulators of cell proliferation, tissue differentiation, embryonic development and apoptosis. We profiled the…”
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Nanostructured all-solid-state supercapacitor based on Li 2 S-P 2 S 5 glass-ceramic electrolyte by Francisco, Brian E., Jones, Christina M., Lee, Se-Hee, Stoldt, Conrad R.

“…While today's lithium-ion batteries offer acceptable energy storage capability, they lack the ability to be cycled repeatedly more than a couple thousand…”
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Abstract LB-351: Comprehensive miRNA profiling of taxane-resistant human breast cancer variants using the SmartChip Real-Time PCR System by Duran, George E., Wang, Cindy Y., Francisco, E. Brian, Wong, Kee, Robinson, Nicole, Sikic, Branimir I.

“…Abstract Background: We derived taxane-resistant variants from four human breast cancer cell lines (MCF-7, BT-549, MDA-MB-231 and T-47D) by continuous exposure…”
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Abstract 1401: SYK promotes tumor progression in ovarian cancer cell lines by Sultan, Aya, Wang, Cindy Y., Duran, George E., Francisco, E. Brian, Berek, Jonathan S., Sikic, Branimir I.

“…Abstract Identification of novel drug targets in ovarian cancers has focused on expression of genes in the tyrosine kinase family. We have previously shown…”
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Abstract 1526: Epithelial mesenchymal transition (EMT) is associated with non-transporter resistance to taxanes in human ovarian cancer cell by Wang, Cindy Y., Duran, George E., Francisco, E. Brian, Juric, Dejan, Witten, Daniela, Tibshrani, Rob, Sikic, Branimir I.

“…Abstract Taxanes are important drugs in the treatment of ovarian cancers, but their efficacy is limited by intrinsic and acquired drug resistance…”
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Abstract 3496: SYK inhibition results in increased sensitivity of OVCAR-3 cells to paclitaxel by Sultan, Aya, Wang, Cindy Y., Duran, George E., Francisco, E. Brian, Berek, Jonathan S., Sikic, Branimir I.

“…Abstract In order to identify novel drug targets in ovarian cancers, we examined our ovarian cancer gene expression microarray data for expression of genes in…”
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Enhanced Ion Conduction via a Diverse Cl-PS4 Anion Lattice in Li3PS4–xLiCl by Wang, Pengbo, Patel, Sawankumar, Roberts, Jason E., Francisco, Brian E., Hu, Yan-Yan

“…Thiophosphates show promise as solid electrolytes for all-solid-state batteries (ASSBs), particularly Li3PS4-based materials, due to their cost-effectiveness…”
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Enhanced Ion Conduction via a Diverse Cl-PS 4 Anion Lattice in Li 3 PS 4 – x LiCl by Wang, Pengbo, Patel, Sawankumar, Roberts, Jason E., Francisco, Brian E., Hu, Yan-Yan

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From Material Design to Device: Structural and Thermodynamic Considerations for Solid-Phase Lithium-Ion Electrolytes by Francisco, Brian E

“…Too often, we check the battery status of our favorite gadget and wonder: "Is it going to make it?" At some point in the not-so-distant future, I believe we…”
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