Search Results - "Francis, Sarah M"

Mitotic chromosome condensation mediated by the retinoblastoma protein is tumor-suppressive by Coschi, Courtney H, Martens, Alison L, Ritchie, Kieran, Francis, Sarah M, Chakrabarti, Subrata, Berube, Nathalie G, Dick, Frederick A

“…Condensation and segregation of mitotic chromosomes is a critical process for cellular propagation, and, in mammals, mitotic errors can contribute to the…”
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Harm Reduction: A Missing Piece to the Holistic Care of Patients Who Inject Drugs by Nolan, Nathanial S, Fracasso Francis, Sarah M, Marks, Laura R, Beekmann, Susan E, Polgreen, Philip M, Liang, Stephen Y, Durkin, Michael J

“…Abstract Background The rise in injection drug use (IDU) has led to an increase in drug-related infections. Harm reduction is an important strategy for…”
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Mutation of the LXCXE binding cleft of pRb facilitates transformation by ras in vitro but does not promote tumorigenesis in vivo by Talluri, Srikanth, Francis, Sarah M, Dick, Frederick A

“…The Retinoblastoma protein (pRB) is a key tumor suppressor that is functionally inactivated in most cancers. pRB regulates the cell division cycle and cell…”
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A G1 Checkpoint Mediated by the Retinoblastoma Protein That Is Dispensable in Terminal Differentiation but Essential for Senescence by Talluri, Srikanth, Isaac, Christian E., Ahmad, Mohammad, Henley, Shauna A., Francis, Sarah M., Martens, Alison L., Bremner, Rod, Dick, Frederick A.

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The Retinoblastoma Protein Regulates Pericentric Heterochromatin by Isaac, Christian E., Francis, Sarah M., Martens, Alison L., Julian, Lisa M., Seifried, Laurie A., Erdmann, Natalie, Binné, Ulrich K., Harrington, Lea, Sicinski, Piotr, Bérubé, Nathalie G., Dyson, Nicholas J., Dick, Frederick A.

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A context-specific role for retinoblastoma protein-dependent negative growth control in suppressing mammary tumorigenesis by Francis, Sarah M, Chakrabarti, Subrata, Dick, Frederick A

“…The ability to respond to anti-growth signals is critical to maintain tissue homeostasis and loss of this negative growth control safeguard is considered a…”
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A Functional Connection between pRB and Transforming Growth Factor β in Growth Inhibition and Mammary Gland Development by Francis, Sarah M., Bergsied, Jacqueline, Isaac, Christian E., Coschi, Courtney H., Martens, Alison L., Hojilla, Carlo V., Chakrabarti, Subrata, DiMattia, Gabriel E., Khoka, Rama, Wang, Jean Y. J., Dick, Frederick A.

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SNS01-T Modulation of eIF5A Inhibits B-cell Cancer Progression and Synergizes With Bortezomib and Lenalidomide by Francis, Sarah M, Taylor, Catherine A, Tang, Terence, Liu, Zhongda, Zheng, Qifa, Dondero, Richard, Thompson, John E

“…The high rates of recurrence and low median survival in many B-cell cancers highlight a need for new targeted therapeutic modalities. In dividing cells,…”
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A cancer derived mutation in the retinoblastoma gene with a distinct defect for LXCXE dependent interactions by Henley, Shauna A, Francis, Sarah M, Demone, Jordan, Ainsworth, Peter, Dick, Frederick A

“…The interaction between viral oncoproteins such as Simian virus 40 TAg, adenovirus E1A, and human papilloma virus E7, and the retinoblastoma protein (pRB)…”
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Potential cost savings associated with dose rounding antineoplastic monoclonal agents by Francis, Sarah M, Heyliger, Alexander, Miyares, Marta A, Viera, Marcos

“…Purpose This study explored the potential financial benefits associated with dose rounding three costly cancer agents: bevacizumab, trastuzumab, and cetuximab…”
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A Retinoblastoma Allele That Is Mutated at Its Common E2F Interaction Site Inhibits Cell Proliferation in Gene-Targeted Mice by Cecchini, Matthew J., Thwaites, Michael J., Talluri, Srikanth, MacDonald, James I., Passos, Daniel T., Chong, Jean-Leon, Cantalupo, Paul, Stafford, Paul M., Sáenz-Robles, M. Teresa, Francis, Sarah M., Pipas, James M., Leone, Gustavo, Welch, Ian, Dick, Frederick A.

“…The retinoblastoma protein (pRB) is best known for regulating cell proliferation through E2F transcription factors. In this report, we investigate the…”
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Internet-Based Institutional Antimicrobial Stewardship Program Resources in Leading US Academic Medical Centers by Gauthier, Timothy P., Lantz, Evan, Heyliger, Alexander, Francis, Sarah M., Smith, Laura

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1535. Harm Reduction: A Missing Piece in Holistic ID Care for Patients Who Inject Drugs by Fracasso Francis, Sarah M, Beekmann, Susan E, Polgreen, Phillip M, Marks, Laura R, Liang, Stephen Y, Durkin, Michael J, Nolan, Nathanial S

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SNS01-T Modulation of elF5A Inhibits B-cell Cancer Progression and Synergizes With Bortezomib and Lenalidomide by Francis, Sarah M, Taylor, Catherine A, Tang, Terence, Liu, Zhongda, Zheng, Qifa, Dondero, Richard, Thompson, John E

“…The high rates of recurrence and low median survival in many B-cell cancers highlight a need for new targeted therapeutic modalities. In dividing cells,…”
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Mutation of the LXCXE Binding Cleft of pRb Facilitates Transformation by ras In Vitro but Does Not Promote Tumorigenesis In Vivo. e72236 by Talluri, Srikanth, Francis, Sarah M, Dick, Frederick A

“…Background The Retinoblastoma protein (pRB) is a key tumor suppressor that is functionally inactivated in most cancers. pRB regulates the cell division cycle…”
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A G 1 Checkpoint Mediated by the Retinoblastoma Protein That Is Dispensable in Terminal Differentiation but Essential for Senescence by Talluri, Srikanth, Isaac, Christian E., Ahmad, Mohammad, Henley, Shauna A., Francis, Sarah M., Martens, Alison L., Bremner, Rod, Dick, Frederick A.

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