Search Results - "Francis, Richard J.B."

Imaging techniques for visualizing and phenotyping congenital heart defects in murine models by Liu, Xiaoqin, Tobita, Kimimasa, Francis, Richard J.B., Lo, Cecilia W.

“…Mouse model is ideal for investigating the genetic and developmental etiology of congenital heart disease. However, cardiovascular phenotyping for the precise…”
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Changes in activin and activin receptor subunit expression in rat liver during the development of CCl4-induced cirrhosis by Gold, Elspeth J, Francis, Richard J B, Zimmermann, Arthur, Mellor, Sally L, Cranfield, Mark, Risbridger, Gail P, Groome, Nigel P, Wheatley, Antony M, Fleming, Jean S

“…Amounts of betaA-activin, betaC-activin, activin receptor subunits ActRIIA and ActRIIB mRNA, and betaA- and betaC-activin subunit protein immunoreactivity were…”
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Autonomous and non-cell autonomous role of cilia in structural birth defects in mice by Francis, Richard J B, San Agustin, Jovenal T, Szabo Rogers, Heather L, Cui, Cheng, Jonassen, Julie A, Eguether, Thibaut, Follit, John A, Lo, Cecilia W, Pazour, Gregory J

“…Ciliopathies are associated with wide spectrum of structural birth defects (SBDs), indicating important roles for cilia in development. Here, we provide novel…”
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Congenital heart disease and the specification of left-right asymmetry by Francis, Richard J B, Christopher, Adam, Devine, William A, Ostrowski, Lawrence, Lo, Cecilia

“…Complex congenital heart disease (CHD) is often seen in conjunction with heterotaxy, the randomization of left-right visceral organ situs. However, the link…”
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Connexin 43 regulates epicardial cell polarity and migration in coronary vascular development by Rhee, David Y, Zhao, Xiao-Qing, Francis, Richard J B, Huang, Guo Ying, Mably, John D, Lo, Cecilia W

“…Connexin 43 knockout (Cx43 KO) mice exhibit conotruncal malformations and coronary artery defects. We observed epicardial blisters in the Cx43 KO hearts that…”
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Ion Torrent sequencing for conducting genome-wide scans for mutation mapping analysis by Damerla, Rama Rao, Chatterjee, Bishwanath, Li, You, Francis, Richard J. B, Fatakia, Sarosh N, Lo, Cecilia W

“…Mutation mapping in mice can be readily accomplished by genome wide segregation analysis of polymorphic DNA markers. In this study, we showed the efficacy of…”
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Initiation and maturation of cilia-generated flow in newborn and postnatal mouse airway by Francis, Richard J B, Chatterjee, Bishwanath, Loges, Niki T, Zentgraf, Hanswalter, Omran, Heymut, Lo, Cecilia W

“…Mucociliary clearance in the adult trachea is well characterized, but there are limited data in newborns. Cilia-generated flow was quantified across…”
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Primordial germ cell deficiency in the connexin 43 knockout mouse arises from apoptosis associated with abnormal p53 activation by Francis, Richard J B, Lo, Cecilia W

“…Connexin 43 knockout (Cx43α1KO) mice exhibit germ cell deficiency, but the underlying cause for the germ cell defect was unknown. Using an Oct4-GFP reporter…”
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Changes in activin and activin receptor subunit expression in rat liver during the development of CCl 4-induced cirrhosis by Gold, Elspeth J., Francis, Richard J.B., Zimmermann, Arthur, Mellor, Sally L., Cranfield, Mark, Risbridger, Gail P., Groome, Nigel P., Wheatley, Antony M., Fleming, Jean S.

“…Amounts of βA-activin, βC-activin, activin receptor subunits ActRIIA and ActRIIB mRNA, and βA- and βC-activin subunit protein immunoreactivity were…”
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Endothelin Receptor A Blockade Ameliorates Hypothermic Ischemia–Reperfusion-Related Microhemodynamic Disturbances during Liver Transplantation in the Rat by Zhang, Xing-yi, Francis, Richard J.B., Sun, Cheuk-kwan, Wheatley, Antony M.

“…Background. The objective of this study was to investigate the effect of graft treatment with specific endothelin receptor antagonists (ETA and ETB) on the…”
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