Search Results - "Francis, Richard J"

Autonomous and non-cell autonomous role of cilia in structural birth defects in mice by Francis, Richard J B, San Agustin, Jovenal T, Szabo Rogers, Heather L, Cui, Cheng, Jonassen, Julie A, Eguether, Thibaut, Follit, John A, Lo, Cecilia W, Pazour, Gregory J

“…Ciliopathies are associated with wide spectrum of structural birth defects (SBDs), indicating important roles for cilia in development. Here, we provide novel…”
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Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton by Cui, Cheng, Chatterjee, Bishwanath, Lozito, Thomas P, Zhang, Zhen, Francis, Richard J, Yagi, Hisato, Swanhart, Lisa M, Sanker, Subramaniam, Francis, Deanne, Yu, Qing, San Agustin, Jovenal T, Puligilla, Chandrakala, Chatterjee, Tania, Tansey, Terry, Liu, Xiaoqin, Kelley, Matthew W, Spiliotis, Elias T, Kwiatkowski, Adam V, Tuan, Rocky, Pazour, Gregory J, Hukriede, Neil A, Lo, Cecilia W

“…Planar cell polarity (PCP) regulates cell alignment required for collective cell movement during embryonic development. This requires PCP/PCP effector…”
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ANKS6 is the critical activator of NEK8 kinase in embryonic situs determination and organ patterning by Czarnecki, Peter G., Gabriel, George C., Manning, Danielle K., Sergeev, Mikhail, Lemke, Kristi, Klena, Nikolai T., Liu, Xiaoqin, Chen, Yu, Li, You, San Agustin, Jovenal T., Garnaas, Maija K., Francis, Richard J., Tobita, Kimimasa, Goessling, Wolfram, Pazour, Gregory J., Lo, Cecilia W., Beier, David R., Shah, Jagesh V.

“…The ciliary kinase NEK8 plays a critical role in situs determination and cystic kidney disease, yet its exact function remains unknown. In this study, we…”
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Ion Torrent sequencing for conducting genome-wide scans for mutation mapping analysis by Damerla, Rama Rao, Chatterjee, Bishwanath, Li, You, Francis, Richard J. B, Fatakia, Sarosh N, Lo, Cecilia W

“…Mutation mapping in mice can be readily accomplished by genome wide segregation analysis of polymorphic DNA markers. In this study, we showed the efficacy of…”
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Congenital heart disease and the specification of left-right asymmetry by Francis, Richard J B, Christopher, Adam, Devine, William A, Ostrowski, Lawrence, Lo, Cecilia

“…Complex congenital heart disease (CHD) is often seen in conjunction with heterotaxy, the randomization of left-right visceral organ situs. However, the link…”
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Imaging techniques for visualizing and phenotyping congenital heart defects in murine models by Liu, Xiaoqin, Tobita, Kimimasa, Francis, Richard J.B., Lo, Cecilia W.

“…Mouse model is ideal for investigating the genetic and developmental etiology of congenital heart disease. However, cardiovascular phenotyping for the precise…”
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Initiation and maturation of cilia-generated flow in newborn and postnatal mouse airway by Francis, Richard J B, Chatterjee, Bishwanath, Loges, Niki T, Zentgraf, Hanswalter, Omran, Heymut, Lo, Cecilia W

“…Mucociliary clearance in the adult trachea is well characterized, but there are limited data in newborns. Cilia-generated flow was quantified across…”
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Connexin 43 regulates epicardial cell polarity and migration in coronary vascular development by Rhee, David Y, Zhao, Xiao-Qing, Francis, Richard J B, Huang, Guo Ying, Mably, John D, Lo, Cecilia W

“…Connexin 43 knockout (Cx43 KO) mice exhibit conotruncal malformations and coronary artery defects. We observed epicardial blisters in the Cx43 KO hearts that…”
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Primordial germ cell deficiency in the connexin 43 knockout mouse arises from apoptosis associated with abnormal p53 activation by Francis, Richard J B, Lo, Cecilia W

“…Connexin 43 knockout (Cx43α1KO) mice exhibit germ cell deficiency, but the underlying cause for the germ cell defect was unknown. Using an Oct4-GFP reporter…”
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Automated identification of abnormal respiratory ciliary motion in nasal biopsies by Quinn, Shannon P, Zahid, Maliha J, Durkin, John R, Francis, Richard J, Lo, Cecilia W, Chennubhotla, S Chakra

“…Motile cilia lining the nasal and bronchial passages beat synchronously to clear mucus and foreign matter from the respiratory tract. This mucociliary defense…”
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Airway ciliary dysfunction and sinopulmonary symptoms in patients with congenital heart disease by Garrod, Andrea S, Zahid, Maliha, Tian, Xin, Francis, Richard J, Khalifa, Omar, Devine, William, Gabriel, George C, Leatherbury, Linda, Lo, Cecilia W

“…Patients with congenital heart disease with heterotaxy exhibit a high prevalence of abnormal airway ciliary motion and low nasal nitric oxide, characteristics…”
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Decellularized tracheal extracellular matrix supports epithelial migration, differentiation, and function by Kutten, Johannes C, McGovern, David, Hobson, Christopher M, Luffy, Sarah A, Nieponice, Alejandro, Tobita, Kimimasa, Francis, Richard J, Reynolds, Susan D, Isenberg, Jeffrey S, Gilbert, Thomas W

“…Tracheal loss is a source of significant morbidity for affected patients with no acceptable solution. Interest in engineering tracheal transplants has created…”
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Heterotaxy and complex structural heart defects in a mutant mouse model of primary ciliary dyskinesia by Tan, Serena Y, Rosenthal, Julie, Zhao, Xiao-Qing, Francis, Richard J, Chatterjee, Bishwanath, Sabol, Steven L, Linask, Kaari L, Bracero, Luciann, Connelly, Patricia S, Daniels, Mathew P, Yu, Qing, Omran, Heymut, Leatherbury, Linda, Lo, Cecilia W

“…Primary ciliary dyskinesia (PCD) is a genetically heterogeneous disorder associated with ciliary defects and situs inversus totalis, the complete mirror image…”
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Endothelin Receptor A Blockade Ameliorates Hypothermic Ischemia–Reperfusion-Related Microhemodynamic Disturbances during Liver Transplantation in the Rat by Zhang, Xing-yi, Francis, Richard J.B., Sun, Cheuk-kwan, Wheatley, Antony M.

“…Background. The objective of this study was to investigate the effect of graft treatment with specific endothelin receptor antagonists (ETA and ETB) on the…”
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Wdpcp, a PCP Protein Required for Ciliogenesis, Regulates Directional Cell Migration and Cell Polarity by Direct Modulation of the Actin Cytoskeleton: e1001720 by Cui, Cheng, Chatterjee, Bishwanath, Lozito, Thomas P, Zhang, Zhen, Francis, Richard J, Yagi, Hisato, Swanhart, Lisa M, Sanker, Subramaniam, Francis, Deanne, Yu, Qing, Agustin, Jovenal TSan, Puligilla, Chandrakala, Chatterjee, Tania, Tansey, Terry, Liu, Xiaoqin, Kelley, Matthew W, Spiliotis, Elias T, Kwiatkowski, Adam V, Tuan, Rocky, Pazour, Gregory J, Hukriede, Neil A, Lo, Cecilia W

“…Planar cell polarity (PCP) regulates cell alignment required for collective cell movement during embryonic development. This requires PCP/PCP effector…”
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Changes in activin and activin receptor subunit expression in rat liver during the development of CCl4-induced cirrhosis by Gold, Elspeth J, Francis, Richard J B, Zimmermann, Arthur, Mellor, Sally L, Cranfield, Mark, Risbridger, Gail P, Groome, Nigel P, Wheatley, Antony M, Fleming, Jean S

“…Amounts of betaA-activin, betaC-activin, activin receptor subunits ActRIIA and ActRIIB mRNA, and betaA- and betaC-activin subunit protein immunoreactivity were…”
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Critical pathways: not just for patients anymore by Francis, R J, Batsie, C

“…Hospital managers initiate a nurse orientation program modeled after critical pathways. The structure allows them to assess nurses' competency while providing…”
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PERCEIVED ROLE OF LOGISTICS INFORMATION IN THE FORMULATION OF VENDOR-SELECTION DECISIONS by POIST, RICHARD FRANCIS, JR

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REFORM IDEAS OF THE ANTI-CORN-LAW LEAGUERS (FREE TRADE, COBDEN, RADICALISM, MANCHESTER SCHOOL, ENGLAND) by SPALL, RICHARD FRANCIS, JR

“…Historians have long recognized the central role of the Anti-Corn-Law League and its members in promoting the cause of repeal of the corn laws and adoption of…”
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Voice onset time in aphasia, apraxia of speech and dysarthria: a review by Pascal Auzou, Canan Ozsancak, Richard J. Morris, Mary Jan, Francis Eustache, Didier Hannequin

“…Voice onset time (VOT) is an objective temporal acoustic parameter defined as the time between the release of the oral constriction for plosive production and…”
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