Search Results - "Francis, Donald P"
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Correlation between Immunologic Responses to a Recombinant Glycoprotein 120 Vaccine and Incidence of HIV-1 Infection in a Phase 3 HIV-1 Preventive Vaccine Trial
Published in The Journal of infectious diseases (01-03-2005)“…BackgroundAn objective of the first efficacy trial of a candidate vaccine containing recombinant human immunodeficiency virus (HIV) type 1 envelope…”
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2
Antibody to HSV gD peptide induced by vaccination does not protect against HSV-2 infection in HSV-2 seronegative women
Published in PloS one (11-05-2017)“…In the HIV-1 vaccine trial RV144, ALVAC-HIV prime with an AIDSVAX® B/E boost reduced HIV-1 acquisition by 31% at 42 months post first vaccination. The bivalent…”
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Safety and reactogenicity of canarypox ALVAC-HIV (vCP1521) and HIV-1 gp120 AIDSVAX B/E vaccination in an efficacy trial in Thailand
Published in PloS one (21-12-2011)“…A prime-boost vaccination regimen with ALVAC-HIV (vCP1521) administered intramuscularly at 0, 4, 12, and 24 weeks and gp120 AIDSVAX B/E at 12 and 24 weeks…”
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IgG Antibody Responses to Recombinant gp120 Proteins, gp70V1/V2 Scaffolds, and a CyclicV2 Peptide in Thai Phase I/II Vaccine Trials Using Different Vaccine Regimens
Published in AIDS research and human retroviruses (01-11-2015)“…RV144 correlates of risk analysis showed that IgG antibodies to gp70V1V2 scaffolds inversely correlated with risk of HIV acquisition. We investigated IgG…”
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Dengue vaccines regulatory pathways: a report on two meetings with regulators of developing countries
Published in PLoS medicine (01-02-2011)“…Abbreviations: DCVRN, Developing Countries' Vaccine Regulators Network; DHF, dengue hemorrhagic fever; DSS, dengue shock syndrome; EMA, European Agency for the…”
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Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand
Published in The New England journal of medicine (03-12-2009)“…With more than 7000 new HIV infections each day, there is a tremendous need for a prophylactic HIV vaccine. In this study involving more than 16,000 largely…”
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HIV-1 Virologic and Immunologic Progression and Initiation of Antiretroviral Therapy among HIV-1–Infected Subjects in a Trial of the Efficacy of Recombinant Glycoprotein 120 Vaccine
Published in The Journal of infectious diseases (15-09-2005)“…The first trial of the efficacy of a human immunodeficiency virus (HIV)–1 vaccine was conducted in North America and The Netherlands between 1998 and 2003…”
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Challenges and successes for the grantees and the Technical Advisory Group of WHO’s influenza vaccine technology transfer initiative
Published in Vaccine (26-10-2016)“…Abstract One of the aims of the WHO Global Action Plan for Influenza Vaccines (GAP) was to transfer influenza vaccine production technology to interested…”
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Phase I/II Study of a Candidate Vaccine Designed Against the B and E Subtypes of HIV-1
Published in Journal of acquired immune deficiency syndromes (1999) (01-09-2004)“…SUMMARYA phase I/II trial of a candidate vaccine to prevent HIV infection was carried out in Bangkok, Thailand, testing AIDSVAX B/E (VaxGen, Inc., Brisbane,…”
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Deadly AIDS policy failure by the highest levels of the US government: A personal look back 30 years later for lessons to respond better to future epidemics
Published in Journal of public health policy (01-08-2012)“…Successful control of any dangerous epidemic requires: (i) early understanding of the epidemiology of the disease and (ii) rapid applications of preventive…”
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Comparison of Antibody Responses Induced by RV144, VAX003, and VAX004 Vaccination Regimens
Published in AIDS research and human retroviruses (01-05-2017)“…The RV144 prime-boost regimen demonstrated efficacy against HIV acquisition while VAX003 and VAX004 did not. Although these trials differed by risk groups,…”
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Safe landing for global polio eradication: A perspective
Published in Vaccine (08-11-2011)“…Abstract After over two decades of immense efforts, the global polio eradication initiative may be approaching its final phase. With leadership from WHO, great…”
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Protecting the public's health: remove the political constraints that hamper the Centers for Disease Control and Prevention
Published in AIDS (London) (01-06-2012)“…With a country as vast and complex as the United States, there is a huge need for technical expertise within its government. The fields of technical expertise…”
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Global vaccine supply. The increasing role of manufacturers from middle income countries
Published in Vaccine (15-09-2014)“…Abstract Hallmarks in the remarkable evolution of vaccines and their application include the eradication of smallpox, the development and delivery of the early…”
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Successes and failures: Worldwide vaccine development and application
Published in Biologicals (01-09-2010)“…The impact that vaccines have had on world health has been great. The misery prevented and the lives saved have been impressive. But all has not been good. As…”
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WHO influenza vaccine technology transfer initiative: Role and activities of the Technical Advisory Group
Published in Vaccine (01-07-2011)“…Abstract In May 2006, the WHO published a Global Pandemic Influenza Action Plan. A significant part of that plan involves the transfer of technology necessary…”
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The Need for a Global HIV Vaccine Enterprise
Published in Science (American Association for the Advancement of Science) (27-06-2003)“…A new collaborative model of research is needed to increase resources, to prioritize the R agenda of the major public- and private-sector stakeholders, and…”
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Long-term immunogenicity and efficacy of hepatitis B vaccine in homosexual men
Published in The New England journal of medicine (24-07-1986)“…To study the duration of antibody persistence and protection provided by the hepatitis B vaccine, we followed 773 homosexual men for five years after…”
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Candidate HIV/AIDS vaccines: lessons learned from the World's first phase III efficacy trials
Published in AIDS (London) (24-01-2003)Get full text
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Recruitment, screening and characteristics of injection drug users participating in the AIDSVAX®B/E HIV vaccine trial, Bangkok, Thailand
Published in AIDS (London) (23-01-2004)“…To describe recruitment, screening and baseline characteristics of injection drug users (IDU) participating in a phase III HIV vaccine (AIDSVAX B/E; VaxGen,…”
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