Search Results - "Francesch, Andrés M"

Stellatolides, a New Cyclodepsipeptide Family from the Sponge Ecionemia acervus: Isolation, Solid-Phase Total Synthesis, and Full Structural Assignment of Stellatolide A by Martín, María Jesús, Rodríguez-Acebes, Raquel, García-Ramos, Yésica, Martínez, Valentín, Murcia, Carmen, Digón, Isabel, Marco, Isabel, Pelay-Gimeno, Marta, Fernández, Rogelio, Reyes, Fernando, Francesch, Andrés M, Munt, Simon, Tulla-Puche, Judit, Albericio, Fernando, Cuevas, Carmen

“…The marine environment is a rich source of metabolites with potential therapeutic properties and applications for humans. Here we describe the first isolation,…”
Get full text

Enzyme-Labile Protecting Groups for the Synthesis of Natural Products: Solid-Phase Synthesis of Thiocoraline by Tulla-Puche, Judit, Góngora-Benítez, Miriam, Bayó-Puxan, Núria, Francesch, Andrés M., Cuevas, Carmen, Albericio, Fernando

“…Another (orthogonal) dimension: The solid‐phase synthesis of thiocoraline was accomplished for the first time by a combined approach involving chemical and…”
Get full text

Solid-Phase Synthesis of Oxathiocoraline by a Key Intermolecular Disulfide Dimer by Tulla-Puche, Judit, Bayó-Puxan, Núria, Moreno, Juan A, Francesch, Andrés M, Cuevas, Carmen, Álvarez, Mercedes, Albericio, Fernando

“…Oxathiocoraline, a member of the quinoxaline antibiotic family, has been synthesized on solid-phase. The depsipeptide exhibits high synthetic complexity owing…”
Get full text

Structure−Activity Relationship of Kahalalide F Synthetic Analogues by Jiménez, José C, López-Macià, Angel, Gracia, Carol, Varón, Sonia, Carrascal, Marta, Caba, Josep M, Royo, Miriam, Francesch, Andrés M, Cuevas, Carmen, Giralt, Ernest, Albericio, Fernando

“…Kahalalide F (KF) is a natural product currently under phase II clinical trials. Here, we report the solid phase synthesis of 132 novel analogues of kahalalide…”
Get full text

Quantitative determination of lurbinectedin, its unbound fraction and its metabolites in human plasma utilizing ultra-performance LC-MS/MS by King, Nicholas, Garcia-Martinez, Soledad, Alcaraz, Eider, Grisalena, Alba, Lubomirov, Rubin, Altares, Raquel, Fernandez-Teruel, Carlos, Francesch, Andrés M, Avilés, Pablo M, Fudio, Salvador

“…Ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) methods to quantify total lurbinectedin, its plasma protein binding to derive the…”
Get full text

The first total synthesis of the cyclodepsipeptide pipecolidepsin A by Pelay-Gimeno, Marta, García-Ramos, Yésica, Jesús Martin, Maria, Spengler, Jan, Molina-Guijarro, José Manuel, Munt, Simon, Francesch, Andrés M., Cuevas, Carmen, Tulla-Puche, Judit, Albericio, Fernando

“…Pipecolidepsin A is a head-to-side-chain cyclodepsipeptide isolated from the marine sponge Homophymia lamellosa . This compound shows relevant cytotoxic…”
Get full text

Lignopurines: A new family of hybrids between cyclolignans and purines. Synthesis and biological evaluation by Castro, Ma Ángeles, Miguel del Corral, José Ma, García, Pablo A., Rojo, Ma Victoria, Bento, Ana C., Mollinedo, Faustino, Francesch, Andrés M., San Feliciano, Arturo

“…A new family of hybrids between cyclolignans related to podophyllic aldehyde, a non-lactonic cyclolignan, and purines were prepared and evaluated against…”
Get full text

Enzyme‐Labile Protecting Groups for the Synthesis of Natural Products: Solid‐Phase Synthesis of Thiocoraline by Tulla‐Puche, Judit, Góngora‐Benítez, Miriam, Bayó‐Puxan, Núria, Francesch, Andrés M., Cuevas, Carmen, Albericio, Fernando

Get full text

Quantitative determination of lurbinectedin, its unbound fraction and its metabolites in human plasma utilizing ultra-performance LC–MS/MS by Nicholas King, Soledad Garcia-Martinez, Eider Alcaraz, Alba Grisalena, Rubin Lubomirov, Raquel Altares, Carlos Fernandez-Teruel, Andrés M. Francesch, Pablo M. Avilés, Salvador Fudio

“…Aims Ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) methods to quantify total lurbinectedin, its plasma protein binding to…”
Get full text

Enzyme-Labile Protecting Groups for the Synthesis of Natural Products: Solid-Phase Synthesis of Thiocoraline by Tulla-Puche, Judit, Góngora-Benítez, Miriam, Bayó-Puxan, Núria, Francesch, Andrés M., Cuevas, Carmen, Albericio, Fernando

“…Gut kombiniert! Durch eine Kombination aus chemischen und enzymatischen Methoden gelang erstmals die Festphasensynthese von Thiocoralin. Schlüsselschritte sind…”
Get full text