Search Results - "François, Olivier"
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Impact of benzodiazepine use on the risk of occupational accidents
Published in PloS one (16-04-2024)“…Benzodiazepines (BZDs) are drugs commonly used for treating insomnia and anxiety. Although they are known to induce cognitive and psychomotor impairments,…”
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Factor analysis of ancient population genomic samples
Published in Nature communications (16-09-2020)“…The recent years have seen a growing number of studies investigating evolutionary questions using ancient DNA. To address these questions, one of the most…”
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Bayesian Clustering Using Hidden Markov Random Fields in Spatial Population Genetics
Published in Genetics (Austin) (01-10-2006)“…We introduce a new Bayesian clustering algorithm for studying population structure using individually geo-referenced multilocus data sets. The algorithm is…”
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Spatially explicit Bayesian clustering models in population genetics
Published in Molecular ecology resources (01-09-2010)“…This article reviews recent developments in Bayesian algorithms that explicitly include geographical information in the inference of population structure…”
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Fast and efficient estimation of individual ancestry coefficients
Published in Genetics (Austin) (01-04-2014)“…Inference of individual ancestry coefficients, which is important for population genetic and association studies, is commonly performed using…”
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Influence of size-reduction on the performances of GaN-based micro-LEDs for display application
Published in Journal of luminescence (01-11-2017)“…Micro-displays based on an array of micro-sized light emitting diodes (µLEDs) are a promising technology for a wide range of applications. In these…”
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7
Neutrophil extracellular traps in ischemic stroke thrombi
Published in Annals of neurology (01-08-2017)“…Objective Neutrophil extracellular traps (NETs) have been shown to promote thrombus formation. Little is known about the exact composition of thrombi that…”
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TESS3: fast inference of spatial population structure and genome scans for selection
Published in Molecular ecology resources (01-03-2016)“…Geography and landscape are important determinants of genetic variation in natural populations, and several ancestry estimation methods have been proposed to…”
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Genome scan methods against more complex models: when and how much should we trust them?
Published in Molecular ecology (01-04-2014)“…The recent availability of next‐generation sequencing (NGS) has made possible the use of dense genetic markers to identify regions of the genome that may be…”
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RNA Helicases DDX5 and DDX17 Dynamically Orchestrate Transcription, miRNA, and Splicing Programs in Cell Differentiation
Published in Cell reports (Cambridge) (26-06-2014)“…The RNA helicases DDX5 and DDX17 are members of a large family of highly conserved proteins that are involved in gene-expression regulation; however, their…”
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Approximate Bayesian Computation (ABC) in practice
Published in Trends in ecology & evolution (Amsterdam) (01-07-2010)“…Understanding the forces that influence natural variation within and among populations has been a major objective of evolutionary biologists for decades…”
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Work accident effect on the use of psychotropic drugs: the case of benzodiazepines
Published in Health economics review (01-12-2023)“…Background A work accident constitutes a shock to health, likely to alter mental states and affect the use of psychotropic drugs. We focus on the use of…”
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Can the behaviour of threespine stickleback parasitized with Schistocephalus solidus be replicated by manipulating host physiology?
Published in Journal of experimental biology (15-01-2017)“…Sticklebacks infected by the parasitic flatworm Schistocephalus solidus show dramatic changes in phenotype, including a loss of species-typical behavioural…”
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14
Adaptive Genetic Variation on the Landscape: Methods and Cases
Published in Annual review of ecology, evolution, and systematics (01-01-2012)“…There is a growing interest in identifying ecological factors that influence adaptive genetic diversity patterns in both model and nonmodel species. The…”
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Genotype-phenotype analysis in 2,405 patients with a dystrophinopathy using the UMD-DMD database: a model of nationwide knowledgebase
Published in Human mutation (01-06-2009)“…UMD-DMD France is a knowledgebase developed through a multicenter academic effort to provide an up-to-date resource of curated information covering all…”
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The Rise and Fall of African Rice Cultivation Revealed by Analysis of 246 New Genomes
Published in Current biology (23-07-2018)“…African rice (Oryza glaberrima) was domesticated independently from Asian rice. The geographical origin of its domestication remains elusive. Using 246 new…”
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Identification of protein features encoded by alternative exons using Exon Ontology
Published in Genome research (01-06-2017)“…Transcriptomic genome-wide analyses demonstrate massive variation of alternative splicing in many physiological and pathological situations. One major…”
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Challenges Raised by Mediation Analysis in a High-Dimension Setting
Published in Environmental health perspectives (01-05-2020)“…Mediation analysis is used in epidemiology to identify pathways through which exposures influence health. The advent of high-throughput (omics) technologies…”
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ADAMTS13-mediated thrombolysis of t-PA–resistant occlusions in ischemic stroke in mice
Published in Blood (12-05-2016)“…Rapid vascular recanalization forms the basis for successful treatment of cerebral ischemia. Currently, tissue plasminogen activator (t-PA) is the only…”
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Studying Stroke Thrombus Composition After Thrombectomy: What Can We Learn?
Published in Stroke (1970) (01-11-2021)“…The composition of ischemic stroke thrombi has gained an increasing amount of interest in recent years. The implementation of endovascular procedures in…”
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