Search Results - "François, Aurélie"

Multimodal Mn-doped I-III-VI quantum dots for near infrared fluorescence and magnetic resonance imaging: from synthesis to in vivo application by Sitbon, Gary, Bouccara, Sophie, Tasso, Mariana, Francois, Aurélie, Bezdetnaya, Lina, Marchal, Frédéric, Beaumont, Marine, Pons, Thomas

“…The development of sensitive multimodal contrast agents is a key issue to provide better global, multi-scale images for diagnostic or therapeutic purposes…”
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A Macrophages-Enriched Head and Neck Tumor Spheroid Model to Study Foslip® Behavior in Tumor Microenvironment by Francois, Aurelie, Dirheimer, Luca, Chateau, Alicia, Lassalle, Henri-Pierre, Yakavets, Ilya, Bezdetnaya, Lina

“…Purpose: The tumor microenvironment (TME) is composed of various stromal components, including immune cells such as tumor-associated macrophages (TAMs), which…”
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Peptide-mediated targeting of Quantum Dots in a 3D model of head and neck cancer by Dirheimer, Luca, Pons, Thomas, François, Aurélie, Lamy, Laureline, Marchal, Frédéric, Dolivet, Gilles, Cortese, Sophie, Bezdetnaya, Lina

“…•αVβ6 integrin is overexpressed in tongue cancer cells•Sulfobetaine polymer coating makes Quantum Dots (QDs) stealthy•Peptide conjugation enables QDs delivery…”
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Photodynamic diagnosis with methyl-5-aminolevulinate in squamous intraepithelial lesions of the vulva: Experimental research by Leufflen, Lea, Francois, Aurelie, Salleron, Julia, Barlier, Catherine, Dolivet, Gilles, Marchal, Frederic, Bezdetnaya, Lina

“…The incidence of the High-grade Squamous Intraepithelial Lesion of the vulva, formerly vulvar intra-epithelial neoplasia is progressively increasing. Today, an…”
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DDB2 expression lights the way for precision radiotherapy response in PDAC cells, with or without olaparib by Dardare, Julie, Witz, Andréa, Betz, Margaux, François, Aurélie, Lamy, Laureline, Husson, Marie, Demange, Jessica, Rouyer, Marie, Lambert, Aurélien, Merlin, Jean-Louis, Gilson, Pauline, Harlé, Alexandre

“…Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers. Therapeutic options for PDAC are primarily restricted to surgery in the early stages…”
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Validation of a high performance functional assay for individual radiosensitivity in pediatric oncology: a prospective cohort study (ARPEGE) by Bernier-Chastagner, Valérie, Hettal, Liza, Gillon, Véronique, Fernandes, Laurinda, Huin-Schohn, Cécile, Vazel, Marion, Tosti, Priscillia, Salleron, Julia, François, Aurélie, Cérimèle, Elise, Perreira, Sandrine, Peiffert, Didier, Chastagner, Pascal, Vogin, Guillaume

“…Approximately 900 children/adolescents are treated with radiotherapy (RT) every year in France. However, among the 80% of survivors, the cumulative incidence…”
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Matryoshka-Type Liposomes Offer the Improved Delivery of Temoporfin to Tumor Spheroids by Yakavets, Ilya, Millard, Marie, Lamy, Laureline, Francois, Aurelie, Scheglmann, Dietrich, Wiehe, Arno, Lassalle, Henri-Pierre, Zorin, Vladimir, Bezdetnaya, Lina

“…The balance between the amount of drug delivered to tumor tissue and the homogeneity of its distribution is a challenge in the efficient delivery of…”
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Photodynamic therapy targeting neuropilin-1: Interest of pseudopeptides with improved stability properties by Thomas, Noémie, Pernot, Marlène, Vanderesse, Régis, Becuwe, Philippe, Kamarulzaman, Ezatul, Da Silva, David, François, Aurélie, Frochot, Céline, Guillemin, François, Barberi-Heyob, Muriel

“…New peptidases-resistant pseudopeptides (aTWLPPR, Aψ[CH 2NH]TWLPPR) and corresponding conjugated photosensitizers were tested, demonstrating a molecular…”
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Quantum dot-folic acid conjugates as potential photosensitizers in photodynamic therapy of cancer by Morosini, Vincent, Bastogne, Thierry, Frochot, Céline, Schneider, Raphaël, François, Aurélie, Guillemin, François, Barberi-Heyob, Muriel

“…This study examined the in vitro potential of bioconjugated quantum dots (QDs) as photosensitizers for photodynamic therapy (PDT). According to our previous…”
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Photodynamic therapy with conventional and PEGylated liposomal formulations of mTHPC (temoporfin): comparison of treatment efficacy and distribution characteristics in vivo by Reshetov, Vadzim, Lassalle, Henri-Pierre, François, Aurélie, Dumas, Dominique, Hupont, Sebastien, Gräfe, Susanna, Filipe, Vasco, Jiskoot, Wim, Guillemin, François, Zorin, Vladimir, Bezdetnaya, Lina

“…A major challenge in the application of a nanoparticle-based drug delivery system for anticancer agents is the knowledge of the critical properties that…”
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Ionizing radiations induce shared epigenomic signatures unraveling adaptive mechanisms of cancerous cell lines with or without methionine dependency by Siblini, Youssef, Chéry, Céline, Rouyer, Pierre, Raso, Jérémie, Julien, Amélia, Hergalant, Sébastien, François, Aurélie, Bezdetnaya, Lina, Vogin, Guillaume, Guéant, Jean-Louis, Oussalah, Abderrahim

“…Although radiation therapy represents a core cancer treatment modality, its efficacy is hampered by radioresistance. The effect of ionizing radiations (IRs) is…”
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CRISPR/Cas9-mediated knock-in of BRCA1/2 mutations restores response to olaparib in pancreatic cancer cell lines by Witz, Andréa, Dardare, Julie, Francois, Aurélie, Husson, Marie, Rouyer, Marie, Demange, Jessica, Merlin, Jean-Louis, Gilson, Pauline, Harlé, Alexandre

“…Pancreatic cancer is one of the most aggressive diseases with a very poor outcome. Olaparib, a PARP inhibitor, as maintenance therapy showed benefits in…”
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Validation of a Three-Dimensional Head and Neck Spheroid Model to Evaluate Cameras for NIR Fluorescence-Guided Cancer Surgery by Egloff-Juras, Claire, Yakavets, Ilya, Scherrer, Victoria, Francois, Aurélie, Bezdetnaya, Lina, Lassalle, Henri-Pierre, Dolivet, Gilles

“…Near-infrared (NIR) fluorescence-guided surgery is an innovative technique for the real-time visualization of resection margins. The aim of this study was to…”
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Age- and sex-related reference values for serum insulin concentration and its biological determinants in a French healthy population. The STANISLAS cohort by François, Aurélie, Maumus, Sandy, Vincent-Viry, Monique, Guéguen, René, Siest, Gérard, Visvikis, Sophie

“…Insulin is involved in coronary heart disease through diabetes and metabolic syndrome. A great deal is known about insulin and its correlates, as well as…”
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Étude exploratoire des caractéristiques professionnelles d'un échantillon de suicidants hospitalisés by François, Stéphane, Garré, Jean-Bernard, Guiho-Bailly, Marie-Pierre, François, Aurélie, Bertin, Chantal, Bodin, Julie, Gohier, Bénédicte, Roquelaure, Yves

“…RésuméCette étude a pour objectif de décrire les caractéristiques professionnelles d’un échantillon de suicidants. Un enquêteur a interrogé les suicidants âgés…”
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Targeting of 3D oral cancer spheroids by αVβ6 integrin using near-infrared peptide-conjugated IRDye 680 by Dirheimer, L, Pons, T, François, A, Lamy, L, Cortese, S, Marchal, F, Bezdetnaya, L

“…In the treatment of oral cavity cancer, margin status is one of the most critical prognostic factors. Positive margins are associated with higher local…”
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Advanced co-culture 3D breast cancer model for investigation of fibrosis induced by external stimuli: optimization study by Yakavets, Ilya, Francois, Aurelie, Benoit, Alice, Merlin, Jean-Louis, Bezdetnaya, Lina, Vogin, Guillaume

“…Radiation-induced fibrosis (RIF) is the main late radiation toxicity in breast cancer patients. Most of the current 3D in vitro breast cancer models are…”
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NIR Imaging of the Integrin-Rich Head and Neck Squamous Cell Carcinoma Using Ternary Copper Indium Selenide/Zinc Sulfide-Based Quantum Dots by Yakavets, Ilya, Francois, Aurelie, Guiot, Maelle, Lequeux, Nicolas, Fragola, Alexandra, Pons, Thomas, Bezdetnaya, Lina, Marchal, Frédéric

“…The efficient intraoperative identification of cancers requires the development of the bright, minimally-toxic, tumor-specific near-infrared (NIR) probes as…”
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Relationship between subcellular localisation of Foscan and caspase activation in photosensitised MCF-7 cells by MARCHAL, S, FRANCOIS, A, DUMAS, D, GUILLEMIN, F, BEZDETNAYA, L

“…The present study investigates the relationship between the subcellular localisation of Foscan and intrinsic apoptotic pathway post Foscan-based photodynamic…”
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DDB2 represses epithelial-to-mesenchymal transition and sensitizes pancreatic ductal adenocarcinoma cells to chemotherapy by Dardare, Julie, Witz, Andréa, Betz, Margaux, Francois, Aurélie, Meras, Morgane, Lamy, Laureline, Lambert, Aurélien, Grandemange, Stéphanie, Husson, Marie, Rouyer, Marie, Demange, Jessica, Merlin, Jean-Louis, Harlé, Alexandre, Gilson, Pauline

“…Damage specific DNA binding protein 2 (DDB2) is an UV-indiced DNA damage recognition factor and regulator of cancer development and progression. DDB2 has dual…”
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