Search Results - "Framroze, Bomi"
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Assessing the Potential of an Enzymatically Liberated Salmon Oil to Support Immune Health Recovery from Acute SARS-CoV-2 Infection via Change in the Expression of Cytokine, Chemokine and Interferon-Related Genes
Published in International journal of molecular sciences (24-06-2024)“…Cytokines, chemokines, and interferons are released in response to viral infection with the ultimate aim of viral clearance. However, in SARS-CoV-2 infection,…”
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Assessing the Potential of Small Peptides for Altering Expression Levels of the Iron-Regulatory Genes FTH1 and TFRC and Enhancing Androgen Receptor Inhibitor Activity in In Vitro Prostate Cancer Models
Published in International journal of molecular sciences (16-10-2023)“…Recent research highlights the key role of iron dyshomeostasis in the pathogenesis of prostate cancer (PCa). PCa cells are heavily dependent on bioavailable…”
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Glucoregulatory Properties of a Protein Hydrolysate from Atlantic Salmon ( Salmo salar ): Preliminary Characterization and Evaluation of DPP-IV Inhibition and Direct Glucose Uptake In Vitro
Published in Marine drugs (28-03-2024)“…Metabolic disorders are increasingly prevalent conditions that manifest pathophysiologically along a continuum. Among reported metabolic risk factors, elevated…”
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Salmon Protein Hydrolysate Potentiates the Growth Inhibitory Effect of Bicalutamide on Human Prostate Cancer Cell Lines LNCaP and PC3 by Modulating Iron Homeostasis
Published in Marine drugs (28-03-2022)“…Prostate cancer is a common cause of cancer death in men. In advanced stages of prostate cancer, androgen deprivation therapy (ADT) is initiated. Despite ADT,…”
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Assessing the Anti-Inflammatory Effects of an Orally Dosed Enzymatically Liberated Fish Oil in a House Dust Model of Allergic Asthma
Published in Biomedicines (01-10-2022)“…Eosinophils are a major driver of inflammation in a number of human diseases, including asthma. Biologic therapies targeting IL-5 have enabled better control…”
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Soluble Protein Hydrolysate Ameliorates Gastrointestinal Inflammation and Injury in 2,4,6-Trinitrobenzene Sulfonic Acid-Induced Colitis in Mice
Published in Biomolecules (Basel, Switzerland) (01-09-2022)“…Inflammatory bowel diseases (IBD) are chronic, recurring gastrointestinal diseases that severely impair health and quality of life. Although therapeutic…”
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Initial Exploration of the In Vitro Activation of GLP-1 and GIP Receptors and Pancreatic Islet Cell Protection by Salmon-Derived Bioactive Peptides
Published in Marine drugs (30-10-2024)“…This study examines the in vitro effects of a soluble protein hydrolysate (SPH) derived from Atlantic salmon (Salmo salar) on incretin receptor activity and…”
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Antiproliferative activity of marine-derived oligopeptides combined with androgen receptor inhibition in preclinical prostate cancer models
Published in Journal of clinical oncology (01-06-2023)“…e15186 Background: Recent cancer statistics reveal a sustained increase in the incidence of prostate cancer (PC) of 3% per year. More than half of this…”
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Assessing the Potential of Small Peptides for Altering Expression Levels of the Iron-Regulatory Genes IFTH1/I and ITFRC/I and Enhancing Androgen Receptor Inhibitor Activity in In Vitro Prostate Cancer Models
Published in International journal of molecular sciences (01-10-2023)“…Recent research highlights the key role of iron dyshomeostasis in the pathogenesis of prostate cancer (PCa). PCa cells are heavily dependent on bioavailable…”
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An in vitro study to explore the modulation of eosinophil effector function in human allergic peripheral blood eosinophils using enzymatically extracted salmonid oil
Published in Functional foods in health and disease (01-08-2020)“…Background: The consumption of oily fish in early childhood diets has been correlated to a reduction in the progression of asthma during adolescence and young…”
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Pharmacological evaluation of the effects of enzymatically liberated fish oil on eosinophilic inflammation in animal models
Published in Biotechnology and applied biochemistry (01-02-2023)“…The inappropriate activation of eosinophils is a well‐recognized driver of various human inflammatory diseases including asthma, chronic rhinitis, and various…”
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Phase Ib, international, dose-escalation study to evaluate the safety, pharmacokinetics (PK) and efficacy of ST-617 for the attenuation of oral mucositis (OM) in patients receiving chemoradiation (CRT) for head and neck (H&N) cancer
Published in Journal of clinical oncology (20-05-2021)“…Abstract only 6075 Background: OM is a common, painful, and costly toxicity associated with cytotoxic regimens used to treat H&N cancers, which may result in…”
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An invitro study on the regulation of oxidative protective genes in human gingival and intestinal epithelial cells after treatment with salmon protein hydrolysate peptides
Published in Functional foods in health and disease (31-08-2018)“…Background: Under physiological conditions, molecular oxygen generates reactive oxygen species (ROS) as metabolic by-products. In the absence of an adequate…”
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Guidance on mucositis assessment from the MASCC Mucositis Study Group and ISOO: an international Delphi studyResearch in context
Published in EClinicalMedicine (01-07-2024)“…Background: Mucositis is a common and highly impactful side effect of conventional and emerging cancer therapy and thus the subject of intense investigation…”
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The effect of industrial processing of salmon oil on its ability to reduce serum concentrations of oxidized low-density lipoprotein- β2-glycoprotein-I complex in a mouse model
Published in Functional foods in health and disease (01-10-2014)“…Background: Circulating serum levels of oxidized low-density lipoprotein, β2-glycoprotein I complex (oxLDL-GP), have been previously correlated with adverse…”
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Comparison of Nitrogen Bioaccessibility from Salmon and Whey Protein Hydrolysates using a Human Gastrointestinal Model (TIM-1)
Published in Functional foods in health and disease (01-05-2014)“…Background: The TIM-1 system is a computer-controlled multi-compartmental dynamic model that closely simulates in vivo gastrointestinal tract digestion in…”
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