Search Results - "Frame, S"

GSK3 takes centre stage more than 20 years after its discovery by Frame, S, Cohen, P

“…Identified originally as a regulator of glycogen metabolism, glycogen synthase kinase-3 (GSK3) is now a well-established component of the Wnt signalling…”
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Mechanisms of Extrahepatic Tumor Induction by Peroxisome Proliferators in Male CD Rats by Biegel, Lisa B., Hurtt, Mark E., Frame, Steven R., O'Connor, John C., Cook, Jon C.

“…Wyeth-14,643 (WY) and ammonium perfluorooctanoate (C8) belong to a diverse class of compounds which have been shown to produce hepatic peroxisome proliferation…”
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Therapeutic potential of novel PLK1 inhibitor CYC140 in esophageal cancer and acute leukemia by Moureau, S, Pohler, E, Kroboth, K, Saladino, C, MacKay, C, Hollick, J, Zheleva, D, Frame, S, Blake, D

“…Background: PLK1 is overexpressed in many cancers, including esophageal cancer and acute leukemia, and elevated expression correlates with disease progression,…”
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STP Position Paper: Best Practice Guideline for the Routine Pathology Evaluation of the Immune System by Haley, P., Perry, R., Ennulat, D., Frame, S., Johnson, C., Lapointe, J-M, Nyska, A., Snyder, P. W., Walker, D., Walter, G.

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A national survey of primary care physicians’ colorectal cancer screening recommendations and practices by Klabunde, Carrie N, Frame, Paul S, Meadow, Ann, Jones, Elizabeth, Nadel, Marion, Vernon, Sally W

“…National data on providers’ colorectal cancer (CRC) screening knowledge, attitudes, and practices are sparse. This study assessed primary care physicians’…”
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Screening for skin cancer by Helfand, Mark, Mahon, Susan M, Eden, Karen B, Frame, Paul S, Orleans, C.Tracy

“…Context: Malignant melanoma is often lethal, and its incidence in the United States has increased rapidly over the past 2 decades. Nonmelanoma skin cancer is…”
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Hospital admissions and deaths relating to deliberate self-harm and accidents within 5 years of a cancer diagnosis: a national study in Scotland, UK by CAMIDGE, D. R, STOCKTON, D. L, FRAME, S, WOOD, R, BAIN, M, BATEMAN, D. N

“…The risk of suicide in cancer patients has been reported as elevated in several countries. These patients are exposed to many medicines that may confuse or…”
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Short-term and long-term outcomes in 133 429 emergency patients admitted with angina or myocardial infarction in Scotland, 1990–2000: population-based cohort study by Capewell, S, Murphy, N F, MacIntyre, K, Frame, S, Stewart, S, Chalmers, J W T, Boyd, J, Finlayson, A, Redpath, A, McMurray, J J V

“…Objective: To analyse short- and long-term outcomes and prognostic factors in a large population-based cohort of unselected patients with a first emergency…”
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Physicians' roles in preventing dental caries in preschool children: A summary of the evidence for the U.S. Preventive Services Task Force by Bader, James D, Rozier, R.Gary, Lohr, Kathleen N, Frame, Paul S

“…Almost 20% of children aged 2 to 5 years have untreated dental caries. Physician interventions to prevent and manage dental caries in preschool children could…”
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Detection of the environmental antiandrogen p, p'-DDE in CD and Long-Evans rats using a Tier I screening battery and a Hershberger assay by O'CONNOR, J. C, FRAME, S. R, DAVIS, L. G, COOK, J. C

“…In this report, p,p'-DDE, a weak androgen receptor (AR) antagonist, has been examined in a Tier I screening battery designed to detect endocrine-active…”
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Hospital discharge rates for suspected acute coronary syndromes between 1990 and 2000: population based analysis by Murphy, N F, MacIntyre, K, Capewell, S, Stewart, S, Pell, J, Chalmers, J, Redpath, A, Frame, S, Boyd, J, McMurray, J J V

“…Murphy et al examined recent trends in hospital population discharge rates for myocardial infarction, angina, and chest pain between 1990 and 2000. The fall in…”
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Benefits of specialisation in the management of pancreatic cancer: results of a Scottish population-based study by PARKS, R. W, BETTSCHART, V, FRAME, S, STOCKTON, D. L, BREWSTER, D. H, GARDEN, O. J

“…Pancreatic cancer is associated with a very poor prognosis; however, in selected patients, resection may improve survival. Several recent reports have…”
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Routine Screening for Lung Cancer?: Maybe Someday, but Not Yet by Frame, Paul S

“…Frame argues that a recommendation for routine lung-cancer screening at this time would impede efforts to understand the best strategies for the early…”
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Evaluation of a Tier I Screening Battery for Detecting Endocrine-Active Compounds (EACs) Using the Positive Controls Testosterone, Coumestrol, Progesterone, and RU486 by O'Connor, John C., Davis, Leonard G., Frame, Steven R., Cook, Jon C.

“…After previously examining 12 compounds with known endocrine activities, we have now evaluated 4 additional compounds in a Tier I screening battery for…”
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Screening for Cancer: Progress, but More Can Be Done by Frame, P S

“…become a reality.REFERENCES(1) [Breen] N, Wagener DK, Brown ML, Davis WW, Ballard-Barbush R. Progress in cancer screening over a decade: results of cancer…”
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Toxicological evaluation of sodium perfluorohexanoate by Loveless, Scott E, Slezak, Brian, Serex, Tessa, Lewis, Joseph, Mukerji, Pushkor, O’Connor, John C, Donner, E. Maria, Frame, Steven R, Korzeniowski, Stephen H, Buck, Robert C

“…Abstract Sodium perfluorohexanoate [NaPFHx, F(CF2 )5 CO2 Na, CAS#2923-26-4] was evaluated in acute, 90-day subchronic, one-generation reproduction,…”
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An Ongoing Validation of a Tier I Screening Battery for Detecting Endocrine-Active Compounds (EACs) by O'Connor, John C., Cook, Jon C., Slone, Theodore W., Makovec, G.Tracy, Frame, Steven R., Davis, Leonard G.

“…After previously examining an estrogen receptor agonist (17β-estradiol), several additional compounds have been evaluated in a Tier I screening battery for…”
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Detection of thyroid toxicants in a Tier I screening battery and alterations in thyroid endpoints over 28 days of exposure by O'CONNOR, J. C, FRAME, S. R, DAVIS, L. G, COOK, J. C

“…Phenobarbital (PB), a thyroid hormone excretion enhancer, and propylthiouracil (PTU), a thyroid hormone-synthesis inhibitor, have been examined in a Tier I…”
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Preventive dentistry: practitioners’ recommendations for low-risk patients compared with scientific evidence and practice guidelines by Frame, Paul S, Sawai, Rebecca, Bowen, William H, Meyerowitz, Cyril

“…Introduction: The purpose of this article is to compare published evidence supporting procedures to prevent dental caries and periodontal disease, in low-risk…”
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Article about Canadian guidelines on proton pump inhibitors was misleading by Frame, Sheila

“…[...]Shuchman writes of a letter that AstraZeneca sent to Dr Anne Holbrook; the letter was sent two years ago to Dr Holbrook as the chair of a government…”
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