Search Results - "Frait, K A"
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Aberrant in vivo T helper type 2 cell response and impaired eosinophil recruitment in CC chemokine receptor 8 knockout mice
Published in The Journal of experimental medicine (05-03-2001)“…Chemokine receptors transduce signals important for the function and trafficking of leukocytes. Recently, it has been shown that CC chemokine receptor (CCR)8…”
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Chemokine Expression Dynamics in Mycobacterial (Type-1) and Schistosomal (Type-2) Antigen-Elicited Pulmonary Granuloma Formation
Published in The American journal of pathology (01-04-2001)“…Transcript expression of 24 chemokines (CKs) was examined throughout 8 days in mouse lungs with type-1 (Th1) or type-2 (Th2) cytokine-mediated granulomas…”
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Chemokine Receptor 1 Knockout Abrogates Natural Killer Cell Recruitment and Impairs Type-1 Cytokines in Lymphoid Tissue during Pulmonary Granuloma Formation
Published in The American journal of pathology (01-12-2000)“…Mice with targeted mutation of chemokine receptor 1 (CCR1) were used to assess the contribution of CCR1 agonists to local, regional, and systemic…”
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IL-13 Transgene State Impairs Mycobacterial (Type-1) and Schistosomal (Type-2) Antigen-Elicited Responses
Published in Cellular immunology (01-11-2001)“…Transgenic technology provides one approach for examining cytokine properties in vivo. This study directly tested the effect of a lung-targeted IL-13 transgene…”
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Differential effects of ageing on cytokine and chemokine responses during type-1 (Mycobacterial) and type-2 (Schistosomal) pulmonary granulomatous inflammation in mice
Published in Mechanisms of ageing and development (01-02-2002)“…Cytokine and chemokine responses during anamnestic type-1 and type-2 lung granuloma formation were evaluated in mice at 6, 12, 18 and 24-months of age. Lesions…”
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