Search Results - "Fraik, Alexandra K"
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Navigating the Interface Between Landscape Genetics and Landscape Genomics
Published in Frontiers in genetics (13-03-2018)“…As next-generation sequencing data become increasingly available for non-model organisms, a shift has occurred in the focus of studies of the geographic…”
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Spatial variation in gene expression of Tasmanian devil facial tumors despite minimal host transcriptomic response to infection
Published in BMC genomics (27-09-2021)“…Transmissible cancers lie at the intersection of oncology and infectious disease, two traditionally divergent fields for which gene expression studies are…”
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Climate change differentially alters distribution of two marten species in a hybrid zone
Published in Ecology and evolution (01-08-2024)“…Species' ranges are shifting rapidly with climate change, altering the composition of biological communities and interactions within and among species…”
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The devil is in the details: Genomics of transmissible cancers in Tasmanian devils
Published in PLoS pathogens (01-08-2018)“…[...]DFT1 is generally composed of pleomorphic round cells in bundles, whereas DFT2 is typically characterized by pleomorphic sheets of cells [9]. [...]DFT2…”
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Disease swamps molecular signatures of genetic-environmental associations to abiotic factors in Tasmanian devil (Sarcophilus harrisii) populations
Published in Evolution (01-07-2020)“…Landscape genomics studies focus on identifying candidate genes under selection via spatial variation in abiotic environmental variables, but rarely by biotic…”
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Contemporary and historical selection in Tasmanian devils ( Sarcophilus harrisii ) support novel, polygenic response to transmissible cancer
Published in Proceedings of the Royal Society. B, Biological sciences (26-05-2021)“…Tasmanian devils ( Sarcophilus harrisii ) are evolving in response to a unique transmissible cancer, devil facial tumour disease (DFTD), first described in…”
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Spontaneous Tumor Regression in Tasmanian Devils Associated with RASL11A Activation
Published in Genetics (Austin) (01-08-2020)“…Abstract Spontaneous cancer regression in humans is uncommon, but understanding the mechanisms is key for advancing treatment. Using Devil Facial Tumor Disease…”
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Large‐effect loci affect survival in Tasmanian devils (Sarcophilus harrisii) infected with a transmissible cancer
Published in Molecular ecology (01-11-2018)“…Identifying the genetic architecture of complex phenotypes is a central goal of modern biology, particularly for disease‐related traits. Genome‐wide…”
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The Impacts of Dam Construction and Removal on the Genetics of Recovering Steelhead ( Oncorhynchus mykiss ) Populations across the Elwha River Watershed
Published in Genes (13-01-2021)“…Dam construction and longitudinal river habitat fragmentation disrupt important life histories and movement of aquatic species. This is especially true for…”
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Correction: Fraik et al. The Impacts of Dam Construction and Removal on the Genetics of Recovering Steelhead (Oncorhynchus mykiss) Populations across the Elwha River Watershed. Genes 2021, 12, 89
Published in Genes (13-09-2022)“…In the original publication [...]…”
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Using riverscape genetics to investigate the genetic response of two species and their life-history forms to dam removal
Published in Frontiers in ecology and evolution (09-11-2023)“…Barriers such as hydroelectric dams inhibit migratory pathways essential to many aquatic species, resulting in significant losses of species, their unique…”
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Transcriptomics of Tasmanian Devil ( Sarcophilus Harrisii ) Ear Tissue Reveals Homogeneous Gene Expression Patterns across a Heterogeneous Landscape
Published in Genes (12-10-2019)“…In an era of unprecedented global change, exploring patterns of gene expression among wild populations across their geographic range is crucial for…”
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