Search Results - "Frahnow, Turid"
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IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling
Published in Nature communications (24-01-2019)“…Activation of endoplasmic reticulum (ER) stress/the unfolded protein response (UPR) has been linked to cancer, but the molecular mechanisms are poorly…”
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Author Correction: IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling
Published in Nature communications (23-07-2024)Get full text
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Heritability and responses to high fat diet of plasma lipidomics in a twin study
Published in Scientific reports (16-06-2017)“…Lipidomics have a great potential as clinical tool for monitoring metabolic changes in health and disease. Nevertheless hardly anything is known about the…”
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An Isocaloric High-Fat Diet Regulates Partially Genetically Determined Fatty Acid and Carbohydrate Uptake and Metabolism in Subcutaneous Adipose Tissue of Lean Adult Twins
Published in Nutrients (16-05-2023)“…The dysfunction of energy metabolism in white adipose tissue (WAT) induces adiposity. Obesogenic diets that are high in saturated fat disturb nutrient…”
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VEGF and GLUT1 are highly heritable, inversely correlated and affected by dietary fat intake: Consequences for cognitive function in humans
Published in Molecular metabolism (Germany) (01-05-2018)“…Reduction of brain glucose transporter GLUT1 results in severe neurological dysfunction. VEGF is required to restore and maintain brain glucose uptake across…”
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High‐Saturated‐Fat Diet Increases Circulating Angiotensin‐Converting Enzyme, Which Is Enhanced by the rs4343 Polymorphism Defining Persons at Risk of Nutrient‐Dependent Increases of Blood Pressure
Published in Journal of the American Heart Association (01-01-2017)“…Background Angiotensin‐converting enzyme (ACE) plays a major role in blood pressure regulation and cardiovascular homeostasis. Contrary to the assumption that…”
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Dietary Fat Intake Modulates Effects of a Frequent ACE Gene Variant on Glucose Tolerance with association to Type 2 Diabetes
Published in Scientific reports (23-08-2017)“…The frequent ACE insertion/deletion polymorphism (I/D) is, albeit inconsistently, associated with impaired glucose tolerance and insulin resistance. We…”
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619-P: An Isocaloric High Saturated Fat Diet Increases Endogenous Cholesterol Production Which Is Reversed by a Protein-Enriched Diet in Normal-Weight Humans
Published in Diabetes (New York, N.Y.) (20-06-2023)“…Lathosterol is a marker of endogenous cholesterol synthesis whereas plant sterols (e. g. campesterol) reflect cholesterol absorption. Obesity and type 2…”
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Isocaloric Diets High in Animal or Plant Protein Reduce Liver Fat and Inflammation in Individuals With Type 2 Diabetes
Published in Gastroenterology (New York, N.Y. 1943) (01-02-2017)“…Background & Aims Nonalcoholic fatty liver disease (NAFLD) is associated with increased risk of hepatic, cardiovascular, and metabolic diseases. High-protein…”
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27-OR: Fatty Acid Uptake and Metabolism in Human Adipose Tissue Is Decreased upon Consuming an Isocaloric High–Saturated Fat Diet and Partially Genetically Determined
Published in Diabetes (New York, N.Y.) (01-06-2022)“…CD36 transports fatty acids (FA) into adipocytes and is increased in white adipose tissue (WAT) in obesity. In rodents, however, it was shown that CD36 knock…”
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710-P: Serum DPP-4 Protein Is Decreased upon Consuming an Isocaloric High Saturated Fat Diet and Genetically Determined in Healthy Human Twins
Published in Diabetes (New York, N.Y.) (01-06-2020)“…Obesity is associated with increased levels of soluble Dipeptidyl Peptidase-4 (DPP-4) in serum leading to adipose tissue inflammation and insulin resistance…”
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Prevalence and Risk Factors of Infection in the Representative COVID-19 Cohort Munich
Published in International journal of environmental research and public health (30-03-2021)“…Given the large number of mild or asymptomatic SARS-CoV-2 cases, only population-based studies can provide reliable estimates of the magnitude of the pandemic…”
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Plasminogen Activator Inhibitor-1 is Regulated Through Dietary Fat Intake and Heritability: Studies in Twins
Published in Twin research and human genetics (01-08-2017)“…In different pathophysiological conditions plasminogen activator inhibitor-1 (PAI-1) plasma concentrations are elevated. As dietary patterns are considered to…”
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