Search Results - "Fraga, Thaís"
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Antibacterial activity of different types of snake venom from the Viperidae family against Staphylococcus aureus
Published in Acta scientiarum. Biological sciences (18-09-2017)“…Toxins and venoms produced by living organisms have exhibited a variety of biological activities against microorganisms. In this study, we tested seven snake…”
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2
Production and characterization of polyurethane foams from a simple mixture of castor oil, crude glycerol and untreated lignin as bio-based polyols
Published in European polymer journal (01-12-2016)“…[Display omitted] •Residual biopolyols were used to synthesize semi-rigid polyurethane foams.•Different content of lignin, castor oil and glycerol were reacted…”
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3
Heparin prevents in vitro glycocalyx shedding induced by plasma from COVID-19 patients
Published in Life sciences (1973) (01-07-2021)“…The severe forms and worsened outcomes of COVID-19 (coronavirus disease 19) are closely associated with hypertension and cardiovascular disease. Endothelial…”
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Polyurethane Foams for Thermal Insulation Uses Produced from Castor Oil and Crude Glycerol Biopolyols
Published in Molecules (Basel, Switzerland) (02-07-2017)“…Rigid polyurethane foams were synthesized using a renewable polyol from the simple physical mixture of castor oil and crude glycerol. The effect of the…”
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5
Mitochondrial DNA and TLR9 activation contribute to SARS-CoV-2-induced endothelial cell damage
Published in Vascular pharmacology (01-02-2022)“…Mitochondria play a central role in the host response to viral infection and immunity, being key to antiviral signaling and exacerbating inflammatory…”
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Naphthoquinone derivatives as potential immunomodulators: prospective for COVID-19 treatment
Published in RSC advances (21-02-2024)“…Inflammation plays a crucial role in COVID-19, and when it becomes dysregulated, it can lead to severe outcomes, including death. Naphthoquinones, a class of…”
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Celastrol: A lead compound that inhibits SARS‐CoV‐2 replication, the activity of viral and human cysteine proteases, and virus‐induced IL‐6 secretion
Published in Drug development research (01-11-2022)“…The global emergence of coronavirus disease 2019 (COVID‐19) has caused substantial human casualties. Clinical manifestations of this disease vary from…”
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Cytokine storm in individuals with severe COVID-19 decreases endothelial cell antioxidant defense via downregulation of the Nrf2 transcriptional factor
Published in American journal of physiology. Heart and circulatory physiology (01-08-2023)“…The cytokine storm in SARS-CoV-2 infection contributes to the onset of inflammation and target-organ damage. The endothelium is a key player in COVID-19…”
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Rare-earth complexes with anti-inflammatory drug sulindac: Synthesis, characterization, spectroscopic and in vitro biological studies
Published in Inorganica Chimica Acta (01-10-2021)“…[Display omitted] •Rare-earth Ce3+, Pr3+, Gd3+, Tb3+, and Ho3+ complexes with sulindac drug were synthesized and characterized.•The general formula…”
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Is the production of reactive oxygen and nitrogen species by macrophages associated with better infectious control in female mice with experimentally disseminated and pulmonary mucormycosis?
Published in PloS one (15-12-2022)“…Different levels of resistance against Rhizopus oryzae infection have been observed between inbred (BALB/c) and outbred (Swiss) mice and are associated with…”
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Cell death induced by NLRP3–palmitate axis impairs pulmonary damage tolerance and aggravates immunopathology during obesity‐tuberculosis comorbidity
Published in The Journal of pathology (01-03-2023)“…A low‐grade and persistent inflammation, which is the hallmark of obesity, requires the participation of NLRP3 and cell death. During Mycobacterium…”
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NOD2 Deficiency Promotes Intestinal CD4+ T Lymphocyte Imbalance, Metainflammation, and Aggravates Type 2 Diabetes in Murine Model
Published in Frontiers in immunology (07-07-2020)“…Type 2 diabetes (T2D) is a metabolic disease characterized by increased inflammation, NOD-like receptors (NLRs) activation and gut dysbiosis. Our research…”
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Alpha 1-acid glycoprotein is upregulated in severe COVID-19 patients and decreases neutrophil NETs in SARS-CoV-2 infection
Published in Cytokine (Philadelphia, Pa.) (01-04-2024)“…Orosomucoid, or alpha-1 acid glycoprotein (AGP), is a major acute-phase protein expressed in response to systemic injury and inflammation. AGP has been…”
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Differential Behavior of Non- albicans Candida Species in the Central Nervous System of Immunocompetent and Immunosuppressed Mice
Published in Frontiers in microbiology (08-01-2019)“…The genus includes commensal fungi that can cause local and systemic infections, frequently involving vital organs as the central nervous system (CNS). spp…”
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Vitamin D Deficiency and Rheumatoid Arthritis
Published in Clinical reviews in allergy & immunology (01-06-2017)“…Vitamin D (VitD) is a hormone primarily synthesized in human skin under the stimulation of ultraviolet radiation. Beyond its endocrine role in bone metabolism,…”
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Efferocytosis of SARS-CoV-2-infected dying cells impairs macrophage anti-inflammatory functions and clearance of apoptotic cells
Published in eLife (06-06-2022)“…COVID-19 is a disease of dysfunctional immune responses, but the mechanisms triggering immunopathogenesis are not established. The functional plasticity of…”
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Crude leaf extracts of Piperaceae species downmodulate inflammatory responses by human monocytes
Published in PloS one (20-06-2018)“…In this study, we aimed to evaluate the immunomodulatory effects of crude leaf extracts from Piper gaudichaudianum Kunth, P. arboreum Aub., P. umbellata L., P…”
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Is there a window of opportunity for the therapeutic use of vitamin D in multiple sclerosis?
Published in Neural regeneration research (01-09-2022)“…Multiple sclerosis is an autoimmune treatable but not curable disease. There are a multiplicity of medications for multiple sclerosis therapy, including a…”
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Photobiomodulation can alter mRNA levels cell death-related
Published in Lasers in medical science (01-09-2019)“…Photobiomodulation (PBM) by low-level laser has demonstrated excellent results for inflammatory treatments, promoting repair of injured tissues. Knowledge…”
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Evaluation of metalloproteinases-2, -9, and -13 post photobiomodulation in mice talocrural joint
Published in Lasers in medical science (01-04-2020)“…The extracellular matrix (ECM) is the main constituent of connective tissue with structural and regulatory functions, stimulating cell differentiation and…”
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