Search Results - "Frade, Amanda"
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Canonical PI3Kγ signaling in myeloid cells restricts Trypanosoma cruzi infection and dampens chagasic myocarditis
Published in Nature communications (17-04-2018)“…Chagas disease is caused by infection with the protozoan Trypanosoma cruzi ( T . cruzi ) and is an important cause of severe inflammatory heart disease…”
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Blood DNA methylation marks discriminate Chagas cardiomyopathy disease clinical forms
Published in Frontiers in immunology (29-09-2022)“…Chagas disease is a parasitic disease from South America, affecting around 7 million people worldwide. Decades after the infection, 30% of people develop…”
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3
Chronic alteration of circadian rhythm is related to impaired lung function and immune response
Published in International journal of clinical practice (Esher) (01-10-2020)“…Alterations of the circadian rhythm negatively impact several aspects of the health, including the lung function. Chronic shiftwork scale classically induces…”
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4
Genetic susceptibility to Chagas disease cardiomyopathy: involvement of several genes of the innate immunity and chemokine-dependent migration pathways
Published in BMC infectious diseases (12-12-2013)“…Chagas disease, caused by the protozoan Trypanosoma cruzi is endemic in Latin America. Thirty percent of infected individuals develop chronic Chagas…”
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Myocardial chemokine expression and intensity of myocarditis in Chagas cardiomyopathy are controlled by polymorphisms in CXCL9 and CXCL10
Published in PLoS neglected tropical diseases (01-10-2012)“…Chronic Chagas cardiomyopathy (CCC), a life-threatening inflammatory dilated cardiomyopathy, affects 30% of the approximately 8 million patients infected by…”
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6
Chitosan/Gold Nanoparticles Nanocomposite Film for Bisphenol A Electrochemical Sensing
Published in Electrochem (Basel, Switzerland) (01-06-2022)“…Bisphenol A (BPA) is considered an endocrine-disrupting compound and can cause toxicological effects, even at low doses. The development of sensitive and…”
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Effect of acupuncture on heart rate variability in individuals with multiple sclerosis: a protocol for a double-blinded randomized controlled trial
Published in Revista brasileira de crescimento e desenvolvimento humano (2023)“…Backgroung: the growing of patients with multiple sclerosis seeking acupuncture treatment is based on clinical reports of improvements in symptoms. Considering…”
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Disease Tolerance and Pathogen Resistance Genes May Underlie Trypanosoma cruzi Persistence and Differential Progression to Chagas Disease Cardiomyopathy
Published in Frontiers in immunology (03-12-2018)“…Chagas disease is caused by infection with the protozoan and affects over 8 million people worldwide. In spite of a powerful innate and adaptive immune…”
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TGFB1 and IL8 gene polymorphisms and susceptibility to visceral leishmaniasis
Published in Infection, genetics and evolution (01-07-2011)“…Visceral leishmaniasis (VL) or Kala-azar is a serious protozoan infectious disease caused by an obligate intracellular parasite. Cytokines have a major role in…”
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miRNAs may play a major role in the control of gene expression in key pathobiological processes in Chagas disease cardiomyopathy
Published in PLoS neglected tropical diseases (01-12-2020)“…Chronic Chagas disease cardiomyopathy (CCC), an especially aggressive inflammatory dilated cardiomyopathy caused by lifelong infection with the protozoan…”
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Myocardial Infarction–Associated Transcript, a Long Noncoding RNA, Is Overexpressed During Dilated Cardiomyopathy Due to Chronic Chagas Disease
Published in The Journal of infectious diseases (01-07-2016)“…Long noncoding RNAs (lncRNAs) modulate gene expression at the epigenetic, transcriptional, and posttranscriptional levels. Dysregulation of the lncRNA known as…”
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Matrix Metalloproteinase 2 and 9 Enzymatic Activities are Selectively Increased in the Myocardium of Chronic Chagas Disease Cardiomyopathy Patients: Role of TIMPs
Published in Frontiers in cellular and infection microbiology (17-03-2022)“…Chronic Chagas disease (CCC) is an inflammatory dilated cardiomyopathy with a worse prognosis compared to other cardiomyopathies. We show the expression and…”
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Western blotting method (TESAcruzi) as a supplemental test for confirming the presence of anti- Trypanosoma cruzi antibodies in finger prick blood samples from children aged 0–5 years in Brazil
Published in Acta tropica (2011)“…Some Latin American countries have plans for total control and/or eradication of Chagas disease by the main vector ( Triatoma infestans) and by blood…”
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Ebi3 Prevents Trypanosoma cruzi- Induced Myocarditis by Dampening IFN-γ-Driven Inflammation
Published in Frontiers in immunology (26-09-2017)“…The identification of anti-inflammatory mediators can reveal important targetable molecules capable of counterbalancing -induced myocarditis. Composed of Ebi3…”
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15
Polymorphism in the alpha cardiac muscle actin 1 gene is associated to susceptibility to chronic inflammatory cardiomyopathy
Published in PloS one (19-12-2013)“…Chagas disease, caused by the protozoan Trypanosoma cruzi is endemic in Latin America, and may lead to a life-threatening inflammatory dilated, chronic Chagas…”
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Functional IL18 polymorphism and susceptibility to Chronic Chagas Disease
Published in Cytokine (Philadelphia, Pa.) (01-05-2015)“…•We have recruited a cohort of Chagas patients (849)+asymptomatic subjects (202).•We genotyped the rs2043055 marker, located in the IL18 gene, on this…”
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Interferon-γ and other inflammatory mediators in cardiomyocyte signaling during Chagas disease cardiomyopathy
Published in World journal of cardiology (26-08-2014)“…Chagas disease cardiomyopathy(CCC), the main consequence of Trypanosoma cruzi(T.cruzi) infection, is an inflammatory cardiomyopathy that develops in up to 30%…”
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Autoimmune Hepatitis in Brazilian Children: IgE and Genetic Polymorphisms in Associated Genes
Published in Journal of immunology research (01-01-2015)“…Pediatric autoimmune hepatitis (AIH) patients present hypergammaglobulinemia, periportal CD8+ cytotoxic T cell infiltration, and cirrhosis. Autoantibody…”
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Polymorphisms in Genes Affecting Interferon-γ Production and Th1 T Cell Differentiation Are Associated With Progression to Chagas Disease Cardiomyopathy
Published in Frontiers in immunology (07-07-2020)“…Chagas disease, caused by the protozoan , is endemic in Latin America. Thirty percent of infected individuals develop chronic Chagas cardiomyopathy (CCC), an…”
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Corrigendum: Polymorphisms in Genes Affecting Interferon-γ Production and Th1 T Cell Differentiation Are Associated With Progression to Chagas Disease Cardiomyopathy
Published in Frontiers in immunology (10-09-2020)“…[This corrects the article DOI: 10.3389/fimmu.2020.01386.]…”
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