Search Results - "Fradale, Laura"

Crystallographic snapshots of a B12-dependent radical SAM methyltransferase by Fyfe, Cameron D., Bernardo-García, Noelia, Fradale, Laura, Grimaldi, Stéphane, Guillot, Alain, Brewee, Clémence, Chavas, Leonard M. G., Legrand, Pierre, Benjdia, Alhosna, Berteau, Olivier

“…By catalysing the microbial formation of methane, methyl-coenzyme M reductase has a central role in the global levels of this greenhouse gas 1 , 2 . The…”
Get full text

Redox-dependent rearrangements of the NiFeS cluster of carbon monoxide dehydrogenase by Wittenborn, Elizabeth C, Merrouch, Mériem, Ueda, Chie, Fradale, Laura, Léger, Christophe, Fourmond, Vincent, Pandelia, Maria-Eirini, Dementin, Sébastien, Drennan, Catherine L

“…The C-cluster of the enzyme carbon monoxide dehydrogenase (CODH) is a structurally distinctive Ni-Fe-S cluster employed to catalyze the reduction of CO to CO…”
Get full text

Ruminococcin C, an anti-clostridial sactipeptide produced by a prominent member of the human microbiota Ruminococcus gnavus by Balty, Clémence, Guillot, Alain, Fradale, Laura, Brewee, Clémence, Boulay, Mylène, Kubiak, Xavier, Benjdia, Alhosna, Berteau, Olivier

“…The human microbiota plays a central role in human physiology. This complex ecosystem is a promising but untapped source of bioactive compounds and antibiotics…”
Get full text

Biosynthesis of the sactipeptide Ruminococcin C by the human microbiome: Mechanistic insights into thioether bond formation by radical SAM enzymes by Balty, Clémence, Guillot, Alain, Fradale, Laura, Brewee, Clémence, Lefranc, Benjamin, Herrero, Christian, Sandström, Corine, Leprince, Jérôme, Berteau, Olivier, Benjdia, Alhosna

“…Despite its major importance in human health, the metabolic potential of the human gut microbiota is still poorly understood. We have recently shown that…”
Get full text

Crystallographic snapshots of a B12-dependent radical SAM methyltransferase involved in methane biosynthesis by Fyfe, Cameron D., Bernardo-García, Noelia, Fradale, Laura, Grimaldi, Stéphane, Guillot, Alain, Brewee, Clémence, Chavas, Leonard M. G., Legrand, Pierre, Benjdia, Alhosna, Berteau, Olivier

“…Abstract only…”
Get full text

Structural and mechanistic basis for RiPP epimerization by a radical SAM enzyme by Kubiak, Xavier, Polsinelli, Ivan, Chavas, Leonard M. G., Fyfe, Cameron D., Guillot, Alain, Fradale, Laura, Brewee, Clémence, Grimaldi, Stéphane, Gerbaud, Guillaume, Thureau, Aurélien, Legrand, Pierre, Berteau, Olivier, Benjdia, Alhosna

“…d -Amino acid residues, found in countless peptides and natural products including ribosomally synthesized and post-translationally modified peptides (RiPPs),…”
Get full text

Interaction of the H‑Cluster of FeFe Hydrogenase with Halides by del Barrio, Melisa, Sensi, Matteo, Fradale, Laura, Bruschi, Maurizio, Greco, Claudio, de Gioia, Luca, Bertini, Luca, Fourmond, Vincent, Léger, Christophe

“…FeFe hydrogenases catalyze H2 oxidation and production using an “H-cluster”, where two Fe ions are bound by an aza-dithiolate (adt) ligand. Various hypotheses…”
Get full text

Photoinhibition of FeFe Hydrogenase by Sensi, Matteo, Baffert, Carole, Fradale, Laura, Gauquelin, Charles, Soucaille, Philippe, Meynial-Salles, Isabelle, Bottin, Hervé, de Gioia, Luca, Bruschi, Maurizio, Fourmond, Vincent, Léger, Christophe, Bertini, Luca

“…In the enzyme FeFe hydrogenase, hydrogen oxidation and production occur at the H-cluster, a Fe6S6 active site that bears intrinsic carbonyl and cyanide…”
Get full text

Crystallographic snapshots of a B 12 -dependent radical SAM methyltransferase by Fyfe, Cameron D, Bernardo-García, Noelia, Fradale, Laura, Grimaldi, Stéphane, Guillot, Alain, Brewee, Clémence, Chavas, Leonard M G, Legrand, Pierre, Benjdia, Alhosna, Berteau, Olivier

“…By catalysing the microbial formation of methane, methyl-coenzyme M reductase has a central role in the global levels of this greenhouse gas . The activity…”
Get full text

Biosynthesis of the sactipeptide Ruminococcin C by the human microbiome: Mechanistic insights into thioether bond formation by radical SAM enzymes by Balty, Clémence, Guillot, Alain, Fradale, Laura, Brewee, Clémence, Lefranc, Benjamin, Herrero, Christian, Sandström, Corine, Leprince, Jérôme, Berteau, Olivier, Benjdia, Alhosna

“…Despite its major importance in human health, the metabolic potential of the human gut microbiota is still poorly understood. We have recently shown that…”
Get full text