Search Results - "Fraccia, Tommaso P."

Liquid Crystal Coacervates Composed of Short Double-Stranded DNA and Cationic Peptides by Fraccia, Tommaso P, Jia, Tony Z

“…Phase separation of nucleic acids and proteins is a ubiquitous phenomenon regulating subcellular compartment structure and function. While complex coacervation…”
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Non-enzymatic oligonucleotide ligation in coacervate protocells sustains compartment-content coupling by Fraccia, Tommaso P., Martin, Nicolas

“…Modern cells are complex chemical compartments tightly regulated by an underlying DNA-encoded program. Achieving a form of coupling between molecular content,…”
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Pairing statistics and melting of random DNA oligomers: Finding your partner in superdiverse environments by Di Leo, Simone, Marni, Stefano, Plata, Carlos A, Fraccia, Tommaso P, Smith, Gregory P, Maritan, Amos, Suweis, Samir, Bellini, Tommaso

“…Understanding of the pairing statistics in solutions populated by a large number of distinct solute species with mutual interactions is a challenging topic,…”
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Backbone-free duplex-stacked monomer nucleic acids exhibiting Watson–Crick selectivity by Smith, Gregory P., Fraccia, Tommaso P., Todisco, Marco, Zanchetta, Giuliano, Zhu, Chenhui, Hayden, Emily, Bellini, Tommaso, Clark, Noel A.

“…We demonstrate that nucleic acid (NA) mononucleotide triphosphates (dNTPs and rNTPs), at sufficiently high concentration and low temperature in aqueous…”
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Liquid Crystal Peptide/DNA Coacervates in the Context of Prebiotic Molecular Evolution by Jia, Tony Z., Fraccia, Tommaso P.

“…Liquid–liquid phase separation (LLPS) phenomena are ubiquitous in biological systems, as various cellular LLPS structures control important biological…”
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Liquid Crystal Ordering and Isotropic Gelation in Solutions of Four-Base-Long DNA Oligomers by Fraccia, Tommaso P, Smith, Gregory P, Bethge, Lucas, Zanchetta, Giuliano, Nava, Giovanni, Klussmann, Sven, Clark, Noel A, Bellini, Tommaso

“…Liquid crystal ordering is reported in aqueous solutions of the oligomer 5′-ATTAp-3′ and of the oligomer 5′-GCCGp-3′. In both systems, we quantitatively…”
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Giant optical nonlinearity in DNA lyotropic liquid crystals by Lucchetti, Liana, Fraccia, Tommaso P, Ciciulla, Fabrizio, Simoni, Francesco, Bellini, Tommaso

“…We report the experimental evidence of nonlinear optical response in DNA lyotropic nematic liquid crystals. Pump-probe experiments indicate that the…”
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Phase separations, liquid crystal ordering and molecular partitioning in mixtures of PEG and DNA oligomers by Di Leo, Simone, Todisco, Marco, Bellini, Tommaso, Fraccia, Tommaso P.

“…Liquid crystals (LCs) ordering of DNA and RNA oligomers relies on the presence of inter-duplex end-to-end attraction, driving the formation of linear…”
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Non-linear optical measurement of the twist elastic constant in thermotropic and DNA lyotropic chiral nematics by Lucchetti, Liana, Fraccia, Tommaso P., Ciciulla, Fabrizio, Bellini, Tommaso

“…Throughout the whole history of liquid crystals science, the balancing of intrinsic elasticity with coupling to external forces has been the key strategy for…”
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Microfluidics-Based Drying-Wetting Cycles to Investigate Phase Transitions of Small Molecules Solutions by Verma, Ajay, Mateo, Tiphaine, Quintero Botero, Juan, Mohankumar, Nishanth, Fraccia, Tommaso P

“…Drying-wetting cycles play a crucial role in the investigation of the origin of life as processes that both concentrate and induce the supramolecular assembly…”
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Liquid crystal self-assembly of random-sequence DNA oligomers by Bellini, Tommaso, Zanchetta, Giuliano, Fraccia, Tommaso P., Cerbino, Roberto, Tsai, Ethan, Smith, Gregory P., Moran, Mark J., Walba, David M., Clark, Noel A.

“…In biological systems and nanoscale assemblies, the self-association of DNA is typically studied and applied in the context of the evolved or directed design…”
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Elasticity and Viscosity of DNA Liquid Crystals by Lucchetti, Liana, Fraccia, Tommaso P, Nava, Giovanni, Turiv, Taras, Ciciulla, Fabrizio, Bethge, Lucas, Klussmann, Sven, Lavrentovich, Oleg D, Bellini, Tommaso

“…Concentrated solutions of blunt-ended DNA oligomer duplexes self-assemble in living polymers and order into lyotropic nematic liquid crystal phase. Using the…”
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Liquid Crystal Ordering of Four-Base-Long DNA Oligomers with Both G–C and A–T Pairing by Fraccia, Tommaso, Smith, Gregory, Clark, Noel, Bellini, Tommaso

“…We report the liquid crystal (LC) ordering in an aqueous solution of four-base-long DNA oligomers 5′-GCTA-3′. In such systems, the formation of the chiral…”
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Simulating the Lyotropic Phase Behavior of a Partially Self-Complementary DNA Tetramer by Cristofaro, Silvia, Querciagrossa, Lara, Soprani, Lorenzo, Fraccia, Tommaso P., Bellini, Tommaso, Berardi, Roberto, Arcioni, Alberto, Zannoni, Claudio, Muccioli, Luca, Orlandi, Silvia

“…DNA oligomers in solution have been found to develop liquid crystal phases via a hierarchical process that involves Watson–Crick base pairing, supramolecular…”
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Nonenzymatic Polymerization into Long Linear RNA Templated by Liquid Crystal Self-Assembly by Todisco, Marco, Fraccia, Tommaso P, Smith, Greg P, Corno, Andrea, Bethge, Lucas, Klussmann, Sven, Paraboschi, Elvezia M, Asselta, Rosanna, Colombo, Diego, Zanchetta, Giuliano, Clark, Noel A, Bellini, Tommaso

“…Self-synthesizing materials, in which supramolecular structuring enhances the formation of new molecules that participate to the process, represent an…”
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A liquid crystal world for the origins of life by Jia, Tony Z, Bellini, Tommaso, Clark, Noel, Fraccia, Tommaso P

“…Nucleic acids (NAs) in modern biology accomplish a variety of tasks, and the emergence of primitive nucleic acids is broadly recognized as a crucial step for…”
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Abiotic ligation of DNA oligomers templated by their liquid crystal ordering by Fraccia, Tommaso P., Smith, Gregory P., Zanchetta, Giuliano, Paraboschi, Elvezia, Yi, Youngwooo, Walba, David M., Dieci, Giorgio, Clark, Noel A., Bellini, Tommaso

“…It has been observed that concentrated solutions of short DNA oligomers develop liquid crystal ordering as the result of a hierarchically structured…”
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Liquid Crystal ordering of DNA Dickerson Dodecamer duplexes with different 5'- Phosphate terminations by Todisco, Marco, Smith, Gregory P., Fraccia, Tommaso P.

“…The onset of liquid crystal (LC) phases in concentrated aqueous solutions of DNA oligomers crucially depends on the end-to-end interaction between the DNA…”
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Evidence of Liquid Crystal–Assisted Abiotic Ligation of Nucleic Acids by Fraccia, Tommaso P., Zanchetta, Giuliano, Rimoldi, Valeria, Clark, Noel A., Bellini, Tommaso

“…The emergence of early life must have been marked by the appearance in the prebiotic era of complex molecular structures and systems, motivating the…”
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Corrigendum: Abiotic ligation of DNA oligomers templated by their liquid crystal ordering by Fraccia, Tommaso P, Smith, Gregory P, Zanchetta, Giuliano, Paraboschi, Elvezia, Yi, Youngwoo, Walba, David M, Dieci, Giorgio, Clark, Noel A, Bellini, Tommaso

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