Search Results - "Fracchioli, Stefano"
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Human Kallikrein 6 (hK6): A New Potential Serum Biomarker for Diagnosis and Prognosis of Ovarian Carcinoma
Published in Journal of clinical oncology (15-03-2003)“…The discovery of new ovarian cancer biomarkers that are suitable for early disease diagnosis and prognosis may ultimately lead to improved patient management…”
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Transcriptional coactivator Drosophila Eyes absent homologue 2 is up-regulated in epithelial ovarian cancer and promotes tumor growth
Published in Cancer research (Chicago, Ill.) (01-02-2005)“…Epithelial ovarian cancer is the most frequent cause of gynecologic malignancy-related mortality in women. To identify genes up-regulated in ovarian cancer,…”
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Higher Human Kallikrein Gene 4 (KLK4) Expression Indicates Poor Prognosis of Ovarian Cancer Patients
Published in Clinical cancer research (01-08-2001)“…Purpose: Kallikrein gene 4 ( KLK4 , also known as prostase/ KLK-L1 ), located on chromosome 19q13.4, is one of the newly discovered members of the human KLK…”
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Prognostic Value of Human Kallikrein 10 Expression in Epithelial Ovarian Carcinoma
Published in Clinical cancer research (01-08-2001)“…Purpose: Human kallikrein 10 (hK10; also known as the normal epithelial cell-specific 1 gene and protein) is a secreted serine protease, which belongs to the…”
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Prognostic Value of the Human Kallikrein Gene 15 Expression in Ovarian Cancer
Published in Journal of clinical oncology (15-08-2003)“…KLK15 is a newly cloned human kallikrein gene. Many kallikreins were found to be differentially expressed in ovarian cancer. Like other kallikreins, KLK15 is…”
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Expression of Endocrine Gland-derived Vascular Endothelial Growth Factor in Ovarian Carcinoma
Published in Clinical cancer research (01-01-2003)“…The first tissue-specific angiogenic molecule, endocrine gland-derived vascular endothelial growth factor (EG-VEGF), was identified recently in human ovary,…”
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Steroid hormone regulation and prognostic value of the human kallikrein gene 14 in ovarian cancer
Published in American journal of clinical pathology (01-03-2003)“…To study KLK14 gene expression in endocrine-related cancers, we studied its hormonal regulation in breast and ovarian cancer cell lines. Our kinetic and…”
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Evidence for a Dose-Response Effect between p53 (but not p21WAF1/Cip1) Protein Concentrations, Survival, and Responsiveness in Patients with Epithelial Ovarian Cancer Treated with Platinum-based Chemotherapy
Published in Clinical cancer research (01-08-2000)“…The prognostic values of p53 and of its downstream mediator p21 WAF1/Cip1 in patients receiving adjuvant chemotherapy for epithelial ovarian cancer have not…”
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Tumor-derived vascular endothelial growth factor up-regulates angiopoietin-2 in host endothelium and destabilizes host vasculature, supporting angiogenesis in ovarian cancer
Published in Cancer research (Chicago, Ill.) (15-06-2003)“…Vascular remodeling in host tissues surrounding growing tumors is implicated in the successful development of tumor neovasculature. Cooperation between…”
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Parallel overexpression of seven kallikrein genes in ovarian cancer
Published in Cancer research (Chicago, Ill.) (01-05-2003)“…Recent evidence suggests that many members of the human kallikrein (KLK) gene family are differentially regulated in ovarian cancer and have potential as…”
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The serum concentration of human kallikrein 10 represents a novel biomarker for ovarian cancer diagnosis and prognosis
Published in Cancer research (Chicago, Ill.) (15-02-2003)“…Human kallikrein 10 (hK10) is a secreted serine protease that is highly expressed in ovarian tissue. We hypothesized that hK10 might represent a novel…”
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Human kallikrein 14: A new potential biomarker for ovarian and breast cancer
Published in Cancer research (Chicago, Ill.) (15-12-2003)“…Human kallikrein gene 14 (KLK14) is a recently discovered member of the tissue kallikrein family of secreted serine proteases, which includes…”
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The RON and MET oncogenes are co-expressed in human ovarian carcinomas and cooperate in activating invasiveness
Published in Experimental cell research (15-08-2003)“…RON is a member of the receptor tyrosine kinase gene family that includes the MET oncogene, whose germline mutations have been causally related to human…”
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The human KLK8 (Neuropsin/Ovasin) gene : Identification of two novel splice variants and its prognostic value in ovarian cancer
Published in Clinical cancer research (01-04-2001)“…KLK8 (neuropsin/ovasin) is a new member of the human kallikrein gene family, which consists of enzymes with serine protease enzymatic activity. Recent reports…”
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The oncogene phosphatidylinositol 3'-kinase catalytic subunit alpha promotes angiogenesis via vascular endothelial growth factor in ovarian carcinoma
Published in Cancer research (Chicago, Ill.) (15-07-2003)“…The gene of phosphatidylinositol 3-kinase catalytic subunit alpha (PIK3CA) has been implicated as an oncogene in ovarian cancer [L. Shayesteh et al., Nat…”
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Quantitative expression of the human kallikrein gene 9 (KLK9) in ovarian cancer : A new independent and favorable prognostic marker
Published in Cancer research (Chicago, Ill.) (01-11-2001)“…Many members of the human kallikrein gene family were found to be differentially expressed in various malignancies and some are useful cancer…”
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Favorable prognostic value of tissue human kallikrein 11 (hK11) in patients with ovarian carcinoma
Published in International journal of cancer (10-09-2003)“…Human kallikrein 11 (hK11/trypsin‐like serine protease/TLSP, encoded by the KLK11 gene) is a member of the kallikrein family of secreted serine proteases…”
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Prognostic value of quantitatively assessed KLK7 expression in ovarian cancer
Published in Clinical biochemistry (01-03-2003)“…Among females, ovarian cancer is the sixth most common malignancy. Women with ovarian cancer have poor overall survival rates, largely because the disease is…”
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The Human KLK8 (Neuropsin/Ovasin) Gene
Published in Clinical cancer research (01-04-2001)“…KLK8 ( neuropsin/ovasin ) is a new member of the human kallikrein gene family, which consists of enzymes with serine protease enzymatic activity. Recent…”
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