Search Results - "Fracassi, Chiara"
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Construction and modelling of an inducible positive feedback loop stably integrated in a mammalian cell-line
Published in PLoS computational biology (01-06-2011)“…Understanding the relationship between topology and dynamics of transcriptional regulatory networks in mammalian cells is essential to elucidate the biology of…”
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miRNAs confer phenotypic robustness to gene networks by suppressing biological noise
Published in Nature communications (30-09-2013)Get full text
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miRNAs confer phenotypic robustness to gene networks by suppressing biological noise
Published in Nature communications (2013)“…miRNAs are small non-coding RNAs able to modulate target gene expression. It has been postulated that miRNAs confer robustness to biological processes, but…”
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Automatic Control of Gene Expression in Mammalian Cells
Published in ACS synthetic biology (15-04-2016)“…Automatic control of gene expression in living cells is paramount importance to characterize both endogenous gene regulatory networks and synthetic circuits…”
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Identification of individual cells from z-stacks of bright-field microscopy images
Published in Scientific reports (30-07-2018)“…Obtaining single cell data from time-lapse microscopy images is critical for quantitative biology, but bottlenecks in cell identification and segmentation must…”
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The non-steroidal anti-inflammatory drug indomethacin activates the eIF2α kinase PKR, causing a translational block in human colorectal cancer cells
Published in Biochemical journal (15-04-2012)“…The NSAID (non-steroidal anti-inflammatory drug) indomethacin, a cyclo-oxygenase-1 and -2 inhibitor with anti-inflammatory and analgesic properties, is known…”
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Metabolic Regulation of the Ultradian Oscillator Hes1 by Reactive Oxygen Species
Published in Journal of molecular biology (22-05-2015)“…Ultradian oscillators are cyclically expressed genes with a period of less than 24h, found in the major signalling pathways. The Notch effector hairy and…”
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Construction and Modelling of an Inducible Positive Feedback Loop Stably Integrated in a Mammalian Cell-Line: e1002074
Published in PLoS computational biology (01-06-2011)“…Understanding the relationship between topology and dynamics of transcriptional regulatory networks in mammalian cells is essential to elucidate the biology of…”
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Journal Article