Carbofilm-covered prostheses in plastic surgery: preliminary observations

Carbofilm-covered prostheses in plastic surgery: preliminary observations

The optimal interface between an implant and the host organism is that which minimizes uncontrolled and irregular growth of fibrous tissue around the foreign material. One way to achieve this goal is to coat the outer surface of the implant with a biocompatible material. A thin film of turbostratic...

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Bibliographic Details
Published in:Plastic and reconstructive surgery (1963) Vol. 91; no. 1; p. 80
Main Authors: Bocchiotti, G, Verna, G, Fracalvieri, M, Fanton, E, Datta, G, Robotti, E
Format: Journal Article
Language:English
Published: United States 01-01-1993
Subjects:
Animals
Biocompatible Materials
Cells, Cultured
Contracture - surgery
Female
Fibroblasts - pathology
Foreign-Body Reaction - pathology
Humans
Mammaplasty
Polyurethanes
Prostheses and Implants
Rats
Silicone Elastomers
Silicones
Surface Properties
Surgery, Plastic
Tissue Expansion Devices
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Summary:The optimal interface between an implant and the host organism is that which minimizes uncontrolled and irregular growth of fibrous tissue around the foreign material. One way to achieve this goal is to coat the outer surface of the implant with a biocompatible material. A thin film of turbostratic carbon (Carbofilm, Sorin Biomedica, Saluggia, Italy) can be applied as a thin coating on tissue expanders and breast implants made of silicone elastomers. The success of biologic trials with such implants in rats and cytologic studies with murine and human fibroblasts encouraged us to employ the Carbofilm technology in clinical situations. Preliminary results indicate that Carbofilm-coated implants satisfy the requirements of an ideal alloplastic material and induce a minimal periprosthetic inflammatory reaction, with the formation of a thin, soft, pliable, fibrous capsule around coated gel-filled silicone implants.
ISSN:0032-1052
DOI:10.1097/00006534-199301000-00011