Search Results - "Fox, Melissa M."
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Dietary energy availability affects primary and metastatic breast cancer and metformin efficacy
Published in Breast cancer research and treatment (01-09-2010)“…Dietary energy restriction has been shown to repress both mammary tumorigenesis and aggressive mammary tumor growth in animal studies. Metformin, a caloric…”
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AMP-Activated Protein Kinase α 2 Isoform Suppression in Primary Breast Cancer Alters AMPK Growth Control and Apoptotic Signaling
Published in Genes & cancer (01-01-2013)“…Adenosine monophosphate-activated protein kinase (AMPK) is a metabolic regulator that promotes energy conservation and restoration when cells are exposed to…”
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AMPKα2 Suppresses Murine Embryonic Fibroblast Transformation and Tumorigenesis
Published in Genes & cancer (01-01-2012)“…AMP-activated kinase (AMPK) is a key metabolic sensor and stress signaling kinase. AMPK activity is known to suppress anabolic processes such as protein and…”
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Abstract 1138: AMPK promotes survival of breast cancer cells by modulating metabolic stress
Published in Cancer research (Chicago, Ill.) (01-08-2015)“…Breast cancer cells can respond to microenvironmental stressors by becoming dormant, that is inhibiting cell proliferation until the environment becomes…”
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Abstract 1092: AMPK alpha 2 promotes tumor cell survival in models of breast cancer dormancy
Published in Cancer research (Chicago, Ill.) (15-04-2013)“…Breast cancer can recur after standard of care treatment, even after many years. As a result, there is a need to identify new ways to treat metastatic…”
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Cloning and expression of a putative metacaspase gene from Schizophyllum commune
Published in The FASEB journal (01-03-2008)“…Abstract only Caspases are essential players in mammalian apoptosis, but their role in the fungal life cycle is not well understood. If the role of apoptosis…”
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Cloning and expression of a putative metacaspase from Schizophyllum commune
Published in The FASEB journal (01-04-2007)“…The goal of this study is to examine the role of apoptosis in the simple eukaryote S. commune. A putative metacaspase has been identified in S. commune using…”
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