Search Results - "Fox, Melanie J."

The exosome component Rrp6 is required for RNA polymerase II termination at specific targets of the Nrd1-Nab3 pathway by Fox, Melanie J, Gao, Hongyu, Smith-Kinnaman, Whitney R, Liu, Yunlong, Mosley, Amber L

“…The exosome and its nuclear specific subunit Rrp6 form a 3'-5' exonuclease complex that regulates diverse aspects of RNA biology including 3' end processing…”
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Rrp6: Integrated roles in nuclear RNA metabolism and transcription termination by Fox, Melanie J., Mosley, Amber L.

“…The yeast RNA exosome is a eukaryotic ribonuclease complex essential for RNA processing, surveillance, and turnover. It is comprised of a barrel‐shaped core…”
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RNA Polymerase II CTD phosphatase Rtr1 fine-tunes transcription termination by Victorino, Jose F, Fox, Melanie J, Smith-Kinnaman, Whitney R, Peck Justice, Sarah A, Burriss, Katlyn H, Boyd, Asha K, Zimmerly, Megan A, Chan, Rachel R, Hunter, Gerald O, Liu, Yunlong, Mosley, Amber L

“…RNA Polymerase II (RNAPII) transcription termination is regulated by the phosphorylation status of the C-terminal domain (CTD). The phosphatase Rtr1 has been…”
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The telomerase template antagonist GRN163L alters MDA-MB-231 breast cancer cell morphology, inhibits growth, and augments the effects of paclitaxel by Goldblatt, Erin M, Gentry, Erin R, Fox, Melanie J, Gryaznov, Sergei M, Shen, Changyu, Herbert, Brittney-Shea

“…Telomeres are repetitive (TTAGGG) n DNA sequences found at the end of chromosomes that protect the ends from recombination, end to end fusions, and recognition…”
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Phosphatase Rtr1 Regulates Global Levels of Serine 5 RNA Polymerase II C-Terminal Domain Phosphorylation and Cotranscriptional Histone Methylation by Hunter, Gerald O., Fox, Melanie J., Smith-Kinnaman, Whitney R., Gogol, Madelaine, Fleharty, Brian, Mosley, Amber L.

“…In eukaryotes, the C-terminal domain (CTD) of Rpb1 contains a heptapeptide repeat sequence of (Y 1 S 2 P 3 T 4 S 5 P 6 S 7 ) n that undergoes reversible…”
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The interactome of the atypical phosphatase Rtr1 in Saccharomyces cerevisiae by Smith-Kinnaman, Whitney R, Berna, Michael J, Hunter, Gerald O, True, Jason D, Hsu, Peter, Cabello, Gabriela I, Fox, Melanie J, Varani, Gabriele, Mosley, Amber L

“…The phosphatase Rtr1 has been implicated in dephosphorylation of the RNA Polymerase II (RNAPII) C-terminal domain (CTD) during transcription elongation and in…”
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Medical genetics and epigenetics of telomerase by Koziel, Jillian E., Fox, Melanie J., Steding, Catherine E., Sprouse, Alyssa A., Herbert, Brittney‐Shea

“…•  Introduction •  Epigenetic regulation of telomerase: recent findings beyond transcriptional control ‐  Methylation ‐  Sirtuins ‐  Non‐coding RNAs • …”
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Lateral drill holes decrease strength of the femur: an observational study using finite element and experimental analyses by Fox, Melanie J, Scarvell, Jennie M, Smith, Paul N, Kalyanasundaram, Shankar, Stachurski, Zbigniew H

“…Internal fixation of femoral fractures requires drilling holes through the cortical bone of the shaft of the femur. Intramedullary suction reduces the fat…”
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Phenotypic plasticity in normal breast derived epithelial cells by Sauder, Candice A M, Koziel, Jillian E, Choi, MiRan, Fox, Melanie J, Grimes, Brenda R, Badve, Sunil, Blosser, Rachel J, Radovich, Milan, Lam, Christina C, Vaughan, Melville B, Herbert, Brittney-Shea, Clare, Susan E

“…Normal, healthy human breast tissue from a variety of volunteer donors has become available for research thanks to the establishment of the Susan G. Komen for…”
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The Exosome Component Rrp6 Is Required for RNA Polymerase II Termination at Specific Targets of the Nrd1-Nab3 Pathway: e1004999 by Fox, Melanie J, Gao, Hongyu, Smith-Kinnaman, Whitney R, Liu, Yunlong, Mosley, Amber L

“…The exosome and its nuclear specific subunit Rrp6 form a 3'-5' exonuclease complex that regulates diverse aspects of RNA biology including 3' end processing…”
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The role of Rtr1 and Rrp6 in rnapii transcription termination by Fox, Melanie J

“…RNA Polymerase II (RNAPII) is responsible for transcription of messenger RNA (mRNA) and many small non-coding RNAs. Progression through the RNAPII…”
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Abstract 3322: Phenotypic plasticity in the normal breast by Sauder, Candice Anne Marcum, Koziel, Jillian E., Choi, MiRan, Fox, Melanie J., Badve, Sunil, Blosser, Rachel J., Mathieson, Theresa, Rufenbarger, Constance A., Henry, Jill E., Storniolo, Anna Maria V., Herbert, Brittney-Shea, Clare, Susan E.

“…Abstract Metaplasia is observed in almost all epithelial cancers. The origins of metaplasia are obscure although chronic inflammation is thought to be one…”
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