Search Results - "Fox, Jayne C."
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Accurate detection of low prevalence AKT1 E17K mutation in tissue or plasma from advanced cancer patients
Published in PloS one (04-05-2017)“…Personalized healthcare relies on accurate companion diagnostic assays that enable the most appropriate treatment decision for cancer patients. Extensive assay…”
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Telomere length and outcomes in ischaemic heart failure: data from the COntrolled ROsuvastatin multiNAtional Trial in Heart Failure (CORONA)
Published in European journal of heart failure (01-03-2015)“…Aims Leucocyte telomere length is considered a marker of biological ageing and has been suggested to be shorter in patients with CAD and heart failure compared…”
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The impact of coronary artery disease risk loci on ischemic heart failure severity and prognosis: association analysis in the COntrolled ROsuvastatin multiNAtional trial in heart failure (CORONA)
Published in BMC genetics (21-12-2014)“…Recent genome-wide association studies have identified multiple loci that are associated with an increased risk of developing coronary artery disease (CAD)…”
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Toward personalized medicine in the neuropsychiatric field
Published in International review of neurobiology (2011)“…There are great expectations for the personalized medicine approach to address the therapeutic needs of patients in the twenty-first century. Advances in human…”
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Amplification refractory mutation system linear extension: a novel, gel-free, enzyme-linked immunoassay method for DNA genotyping
Published in Diagnostic molecular pathology (01-10-1998)“…A single synthesis cycle of the amplification refractory mutation system (ARMS) was applied to the analysis of K-ras alleles amplified by polymerase chain…”
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K-ras Point Mutation Detection in Lung Cancer: Comparison of Two Approaches to Somatic Mutation Detection Using ARMS Allele-specific Amplification
Published in Clinical chemistry (Baltimore, Md.) (01-12-2000)“…The use of sensitive molecular techniques to detect rare cells in a population is of increasing interest to the molecular pathologist, but detection limits…”
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Longitudinal analysis of cytomegalovirus load in renal transplant recipients using a quantitative polymerase chain reaction: correlation with disease
Published in Journal of general virology (01-02-1995)“…1 Division of Communicable Diseases, Royal Free Hampstead NHS Trust and School of Medicine, Rowland Hill Street, Hampstead, London NW3 2PF, UK and 2 Renal…”
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K- ras mutations in colonic enema washings: Implications for molecular screening
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2000)Get full text
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Quantification of human cytomegalovirus DNA using the polymerase chain reaction
Published in Journal of general virology (01-09-1992)“…University Division of Communicable Diseases, Royal Free Hospital School of Medicine, Rowland Hill Street, London NW3 2PF, U.K. The important goal of…”
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ARMSallele-specific amplification-based detection of mutant p53 DNA and mRNA in tumors of the breast
Published in Clinical chemistry (Baltimore, Md.) (2001)Get full text
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ARMS allele-specific amplification-based detection of mutant p53 DNA and mRNA in tumors of the breast
Published in Clinical chemistry (Baltimore, Md.) (01-04-2001)Get full text
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Eliminating PCR contamination: is UV irradiation the answer?
Published in Journal of virological methods (01-08-1991)“…The sensitivity of the polymerase chain reaction (PCR) can mean that even very low levels of contamination with the target DNA will result in a positive…”
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DNA ethylations induced by ethylnitrosourea in the wild type, cdc4 and cdc7 strains of Saccharomyces cerevisiae
Published in Mutagenesis (01-05-1986)“…The experiments reported here have investigated the induction of ethylations to DNA in yeast cells exposed to the chemical mutagen ethylnitrosourea. A similar…”
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Evidence to support the existence of efficient DNA double-strand break rejoining in a radiosensitive mutant of V79-4 following irradiation with 250 kVp X-rays or neutrons
Published in Mutation research (01-03-1990)“…The repair of ionising-radiation-induced DNA double-strand break type damage was measured by Kohn neutral elution in an X-ray-sensitive mutant of V79-4, irs1…”
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