Search Results - "Fowler, Stephen J."

Dysfunctional breathing: a review of the literature and proposal for classification by Boulding, Richard, Stacey, Rebecca, Niven, Rob, Fowler, Stephen J

“…Dysfunctional breathing is a term describing breathing disorders where chronic changes in breathing pattern result in dyspnoea and other symptoms in the…”
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High blood eosinophil counts predict sputum eosinophilia in patients with severe asthma by Fowler, Stephen J., MD, Tavernier, Gaël, PhD, Niven, Robert, MD

“…[...]we have shown that using a cutoff of 0.45 x 109 cells/L for blood eosinophilia can usefully predict airway eosinophilia in patients with severe asthma…”
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Breathomics in the setting of asthma and chronic obstructive pulmonary disease by Bos, Lieuwe D., MSc, PhD, Sterk, Peter J., MD, PhD, Fowler, Stephen J., MD, PhD

“…Exhaled breath contains thousands of volatile organic compounds that reflect the metabolic process occurring in the host both locally in the airways and…”
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Exhaled breath analysis: a review of ‘breath-taking’ methods for off-line analysis by Lawal, Oluwasola, Ahmed, Waqar M., Nijsen, Tamara M. E., Goodacre, Royston, Fowler, Stephen J.

“…Background The potential of exhaled breath sampling and analysis has long attracted interest in the areas of medical diagnosis and disease monitoring. This…”
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Laryngeal Dysfunction: Assessment and Management for the Clinician by Hull, James H, Backer, Vibeke, Gibson, Peter G, Fowler, Stephen J

“…The larynx is one of the most highly innervated organs in humans and serves a number of vitally important, complex, and highly evolved biological functions. On…”
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Exhaled breath testing – A tool for the clinician and researcher by Davis, Michael D., Fowler, Stephen J., Montpetit, Alison J.

“…Exhaled breath is a robust matrix of biomarkers divided between three fractions – gaseous breath, volatile breath, and breath condensate. Breath is collected…”
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Expiratory flow limitation development index (ELDI): a novel method of assessing respiratory mechanics in COPD by Dean, James, Fowler, Stephen J, Singh, Dave, Beech, Augusta

“…Expiratory flow limitation (EFL) can be detected using oscillometric reactance and is associated with a worse clinical presentation in chronic obstructive…”
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Capsaicin-evoked cough responses in asthmatic patients: Evidence for airway neuronal dysfunction by Satia, Imran, MD, Tsamandouras, Nikolaos, PhD, Holt, Kimberley, MPhil, Badri, Huda, MD, Woodhead, Mark, MD, Ogungbenro, Kayode, PhD, Felton, Timothy W., PhD, O'Byrne, Paul M., MD, Fowler, Stephen J., MD, Smith, Jaclyn A., PhD

“…Background Cough in asthmatic patients is a common and troublesome symptom. It is generally assumed coughing occurs as a consequence of bronchial…”
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Taking your breath away: metabolomics breathes life in to personalized medicine by Rattray, Nicholas J.W, Hamrang, Zahra, Trivedi, Drupad K, Goodacre, Royston, Fowler, Stephen J

“…Highlights • Breathomics is an upcoming bioanalytical area transforming point-of-care diagnostics. • Volatile organic compounds (VOCs) are an important source…”
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Burden of fungal asthma in Africa: A systematic review and meta-analysis by Kwizera, Richard, Musaazi, Joseph, Meya, David B, Worodria, William, Bwanga, Freddie, Kajumbula, Henry, Fowler, Stephen J, Kirenga, Bruce J, Gore, Robin, Denning, David W

“…Asthma is one of the neglected diseases in Africa with a high prevalence. Allergic fungal diseases have been reported to complicate asthma progression and…”
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Perspectives of patients and healthcare professionals on mHealth for asthma self-management by Simpson, Andrew J, Honkoop, Persijn J, Kennington, Erika, Snoeck-Stroband, Jiska B, Smith, Ian, East, Jessica, Coleman, Courtney, Caress, Ann, Chung, Kian Fan, Sont, Jacob K, Usmani, Omar, Fowler, Stephen J

“…Mobile healthcare (mHealth) has the potential to revolutionise the self-management of long-term medical conditions such as asthma. A user-centred design is…”
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Objective Cough Frequency, Airway Inflammation, and Disease Control in Asthma by Marsden, Paul A., MD, PhD, Satia, Imran, MD, Ibrahim, Baharudin, PhD, Woodcock, Ashley, MD, Yates, Lucy, BSc (Hons), Donnelly, Iona, BSc, Jolly, Lisa, BSc, Thomson, Neil C., MD, PhD, Fowler, Stephen J., MD, Smith, Jaclyn A., MD, PhD

“…Background Cough is recognized as an important troublesome symptom in the diagnosis and monitoring of asthma. Asthma control is thought to be determined by the…”
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The interaction between bronchoconstriction and cough in asthma by Satia, Imran, Badri, Huda, Woodhead, Mark, O'Byrne, Paul M, Fowler, Stephen J, Smith, Jaclyn A

“…Variable airflow obstruction is a pathophysiological hallmark of asthma; however, the interactions between acute bronchoconstriction and the cough reflex are…”
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Time of Day Affects Eosinophil Biomarkers in Asthma: Implications for Diagnosis and Treatment by Durrington, Hannah J, Gioan-Tavernier, Gael O, Maidstone, Robert J, Krakowiak, Karolina, Loudon, Andrew S I, Blaikley, John F, Fowler, Stephen J, Singh, Dave, Simpson, Angela, Ray, David W

“…Groups were well matched for age (P = 0.11), body mass index (P = 0.25), FEV1% predicted (P = 0.85), smoking status (P = 0.3), serum total IgE (P = 0.23),…”
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Exhaled Volatile Organic Compounds of Infection: A Systematic Review by Ahmed, Waqar M, Lawal, Oluwasola, Nijsen, Tamara M, Goodacre, Royston, Fowler, Stephen J

“…With heightened global concern of microbial drug resistance, advanced methods for early and accurate diagnosis of infection are urgently needed. Analysis of…”
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Application of 'omics technologies to biomarker discovery in inflammatory lung diseases by WHEELOCK, Craig E, GOSS, Victoria M, CHAIBOONCHOE, Amphun, AHMED, Hassan, BALLEREAU, Stéphane, ROSSIOS, Christos, KIAN FAN CHUNG, MONTUSCHI, Paolo, FOWLER, Stephen J, ADCOCK, Ian M, POSTLE, Anthony D, DAHLEN, Sven-Erik, BALGOMA, David, ROWE, Anthony, STERK, Peter J, AUFFRAY, Charles, DJUKANOVIC, Ratko, NICHOLAS, Ben, BRANDSMA, Joost, SKIPP, Paul J, SNOWDEN, Stuart, BURG, Dominic, D'AMICO, Arnaldo, HORVATH, Ildiko

“…Inflammatory lung diseases are highly complex in respect of pathogenesis and relationships between inflammation, clinical disease and response to treatment…”
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Breath biomarkers in idiopathic pulmonary fibrosis: a systematic review by Hayton, Conal, Terrington, Dayle, Wilson, Andrew M, Chaudhuri, Nazia, Leonard, Colm, Fowler, Stephen J

“…Exhaled biomarkers may be related to disease processes in idiopathic pulmonary fibrosis (IPF) however their clinical role remains unclear. We performed a…”
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Composition and diversity analysis of the lung microbiome in patients with suspected ventilator-associated pneumonia by Fenn, Dominic, Abdel-Aziz, Mahmoud I., van Oort, Pouline M. P., Brinkman, Paul, Ahmed, Waqar M., Felton, Timothy, Artigas, Antonio, Póvoa, Pedro, Martin-Loeches, Ignacio, Schultz, Marcus J., Dark, Paul, Fowler, Stephen J., Bos, Lieuwe D. J., Raventos, Antonio Artigas, Bannard-Smith, Jonathan, Camprubi, Marta, Coelho, Luis, Davie, Alan, Diaz, Emili, Goma, Gemma, Goodacre, Royston, Johnson, Craig, Knobel, Hugo, Lawal, Oluwasola, Leopold, Jan-Hendrik, Nijsen, Tamara M. E., Povoa, Pedro, Rattray, Nicholas J. W., Rijnders, Guus, Steenwelle, Ruud, Sterk, Peter J., Valles, Jordi, Verhoeckx, Fred, Vink, Anton, Weda, Hans, White, Iain R., Winters, Tineke, Zakharkina, Tetyana

“…Abstract Background Ventilator-associated pneumonia (VAP) is associated with high morbidity and health care costs, yet diagnosis remains a challenge. Analysis…”
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Breath and plasma metabolomics to assess inflammation in acute stroke by Ahmed, Waqar, White, Iain R., Wilkinson, Maxim, Johnson, Craig F., Rattray, Nicholas, Kishore, Amit K., Goodacre, Royston, Smith, Craig J., Fowler, Stephen J.

“…Inflammation is strongly implicated in both injury and repair processes occurring after stroke. In this exploratory study we assessed the feasibility of…”
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Evaluation of an Aspergillus IgG/IgM lateral flow assay for serodiagnosis of fungal asthma in Uganda by Kwizera, Richard, Bongomin, Felix, Olum, Ronald, Worodria, William, Bwanga, Freddie, Meya, David B, Kirenga, Bruce J, Gore, Robin, Denning, David W, Fowler, Stephen J

“…Background Diagnosis of fungal allergies in asthma remains problematic in low-and middle-income countries due to non-availability of point-of-care testing. In…”
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