Search Results - "Fowler, Stephanie W"

NFκB-activated astroglial release of complement C3 compromises neuronal morphology and function associated with Alzheimer's disease by Lian, Hong, Yang, Li, Cole, Allysa, Sun, Lu, Chiang, Angie C-A, Fowler, Stephanie W, Shim, David J, Rodriguez-Rivera, Jennifer, Taglialatela, Giulio, Jankowsky, Joanna L, Lu, Hui-Chen, Zheng, Hui

“…Abnormal NFκB activation has been implicated in Alzheimer's disease (AD). However, the signaling pathways governing NFκB regulation and function in the brain…”
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Humanized Tau Mice with Regionalized Amyloid Exhibit Behavioral Deficits but No Pathological Interaction by Yetman, Michael J, Fowler, Stephanie W, Jankowsky, Joanna L

“…Alzheimer's disease (AD) researchers have struggled for decades to draw a causal link between extracellular Aβ aggregation and intraneuronal accumulation of…”
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Vaginal microbial dynamics and pathogen colonization in a humanized microbiota mouse model by Mejia, Marlyd E., Mercado-Evans, Vicki, Zulk, Jacob J., Ottinger, Samantha, Ruiz, Korinna, Ballard, Mallory B., Fowler, Stephanie W., Britton, Robert A., Patras, Kathryn A.

“…Vaginal microbial composition is associated with differential risk of urogenital infection. Although Lactobacillus spp. are thought to confer protection…”
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Site-specific pathophysiology in a neonatal mouse model of gastroparesis by Edwards, Price T, Soni, Krishnakant G, Conner, Margaret E, Fowler, Stephanie W, Foong, Jaime P P, Stavely, Rhian, Cheng, Lily S, Preidis, Geoffrey A

“…Early-life events impact maturation of the gut microbiome, enteric nervous system, and gastrointestinal motility. We examined three regions of gastric tissue…”
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Genetic modulation of soluble Aβ rescues cognitive and synaptic impairment in a mouse model of Alzheimer's disease by Fowler, Stephanie W, Chiang, Angie C A, Savjani, Ricky R, Larson, Megan E, Sherman, Mathew A, Schuler, Dorothy R, Cirrito, John R, Lesné, Sylvain E, Jankowsky, Joanna L

“…An unresolved debate in Alzheimer's disease (AD) is whether amyloid plaques are pathogenic, causing overt physical disruption of neural circuits, or…”
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Timing of gestational exposure to Zika virus is associated with postnatal growth restriction in a murine model by Valentine, Gregory C., Seferovic, Maxim D., Fowler, Stephanie W., Major, Angela M., Gorchakov, Rodion, Berry, Rebecca, Swennes, Alton G., Murray, Kristy O., Suter, Melissa A., Aagaard, Kjersti M.

“…Vertical transmission of Zika virus leads to infection of neuroprogenitor cells and destruction of brain parenchyma. Recent evidence suggests that the timing…”
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Discrete Pools of Oligomeric Amyloid-β Track with Spatial Learning Deficits in a Mouse Model of Alzheimer Amyloidosis by Chiang, Angie C.A., Fowler, Stephanie W., Reddy, Rohit, Pletnikova, Olga, Troncoso, Juan C., Sherman, Mathew A., Lesne, Sylvain E., Jankowsky, Joanna L.

“…Despite increasing appreciation that oligomeric amyloid-β (Aβ) may contribute to cognitive decline of Alzheimer disease, defining the most critical forms has…”
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Combination anti-Aβ treatment maximizes cognitive recovery and rebalances mTOR signaling in APP mice by Chiang, Angie C A, Fowler, Stephanie W, Savjani, Ricky R, Hilsenbeck, Susan G, Wallace, Clare E, Cirrito, John R, Das, Pritam, Jankowsky, Joanna L

“…Drug development for Alzheimer's disease has endeavored to lower amyloid β (Aβ) by either blocking production or promoting clearance. The benefit of combining…”
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Impairments in experience-dependent scaling and stability of hippocampal place fields limit spatial learning in a mouse model of Alzheimer's disease by Zhao, Rong, Fowler, Stephanie W., Chiang, Angie C.A., Ji, Daoyun, Jankowsky, Joanna L.

“…ABSTRACT Impaired spatial memory characterizes many mouse models for Alzheimer's disease, but we understand little about how this trait arises. Here, we use a…”
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Cerebral Vascular Leak in a Mouse Model of Amyloid Neuropathology by Tanifum, Eric A, Starosolski, Zbigniew A, Fowler, Stephanie W, Jankowsky, Joanna L, Annapragada, Ananth V

“…In Alzheimer's disease (AD), there is increasing evidence of blood–brain barrier (BBB) compromise, usually observed as ‘microbleeds’ correlated with amyloid…”
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Effects of Swim Stress on Neophobia and Reconditioning Using a Conditioned Taste Aversion Procedure by Walker, Jennifer M, Ramsey, Ashley K, Fowler, Stephanie W, Schachtman, Todd R

“…Previous research has found that swim stress during a classical conditioning trial attenuates conditioned taste aversion (CTA). In the current study, rats were…”
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Bacteroides ovatus alleviates dysbiotic microbiota-induced graft-versus-host disease by Hayase, Eiko, Hayase, Tomo, Mukherjee, Akash, Stinson, Stuart C, Jamal, Mohamed A, Ortega, Miriam R, Sanchez, Christopher A, Ahmed, Saira S, Karmouch, Jennifer L, Chang, Chia-Chi, Flores, Ivonne I, McDaniel, Lauren K, Brown, Alexandria N, El-Himri, Rawan K, Chapa, Valerie A, Tan, Lin, Tran, Bao Q, Xiao, Yao, Fan, Christopher, Pham, Dung, Halsey, Taylor M, Jin, Yimei, Tsai, Wen-Bin, Prasad, Rishika, Glover, Israel K, Enkhbayar, Altai, Mohammed, Aqsa, Schmiester, Maren, King, Katherine Y, Britton, Robert A, Reddy, Pavan, Wong, Matthew C, Ajami, Nadim J, Wargo, Jennifer A, Shelburne, Samuel, Okhuysen, Pablo C, Liu, Chen, Fowler, Stephanie W, Conner, Margaret E, Katsamakis, Zoe, Smith, Natalie, Burgos da Silva, Marina, Ponce, Doris M, Peled, Jonathan U, van den Brink, Marcel R M, Peterson, Christine B, Rondon, Gabriela, Molldrem, Jeffrey J, Champlin, Richard E, Shpall, Elizabeth J, Lorenzi, Philip L, Mehta, Rohtesh S, Martens, Eric C, Alousi, Amin M, Jenq, Robert R

“…Acute lower gastrointestinal GVHD (aLGI-GVHD) is a serious complication of allogeneic hematopoietic stem cell transplantation. Although the intestinal…”
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Impairments in experience-dependent scaling and stability of hippocampal place fields limit spatial learning in a mouse model of Alzheimer's disease: Impaired Place Field Scaling and Stability in App Mice by Zhao, Rong, Fowler, Stephanie W., Chiang, Angie C.A., Ji, Daoyun, Jankowsky, Joanna L.

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Effects of Swim Stress on Ne ophobia and Re conditioning Using a Conditioned Taste Aversion Procedure by Walker, Jennifer M., Ramsey, Ashley K., Fowler, Stephanie W., Schachtman, Todd R.

“…Previous research has found that swim stress during a classical conditioning trial attenuates conditioned taste aversion (CTA). In the current study, rats were…”
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