Search Results - "Fowler, M. M."

Deep mutational scanning: a new style of protein science by Fowler, Douglas M, Fields, Stanley

“…This Perspective discusses the power of large mutational scans for the study of protein properties, the analytical challenges posed by the resulting data sets…”
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Electrochemical thermal modeling and experimental measurements of 18650 cylindrical lithium-ion battery during discharge cycle for an EV by Panchal, S., Mathew, M., Fraser, R., Fowler, M.

“…•Designed and developed the battery thermal testing system.•Developed ECT model using ANSYS Fluent.•Studied the temperature and voltage profile at different…”
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Thermal design and simulation of mini-channel cold plate for water cooled large sized prismatic lithium-ion battery by Panchal, S., Khasow, R., Dincer, I., Agelin-Chaab, M., Fraser, R., Fowler, M.

“…•Design of battery thermal management system with water cooling for LFP battery.•Design of mini-channel cold plates in NX and meshing in ICEM-CFD.•ANSYS CFD…”
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Experimental Investigation of a New Passive Thermal Management System for a Li-Ion Battery Pack Using Phase Change Composite Material by Malik, M., Dincer, I., Rosen, M., Fowler, M.

“…A pack level passive thermal management system has been designed, developed and experimentally investigated using a phase change composite material. Three 20Ah…”
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Tropomodulins and Leiomodins: Actin Pointed End Caps and Nucleators in Muscles by Fowler, Velia M., Dominguez, Roberto

“…Cytoskeletal structures characterized by actin filaments with uniform lengths, including the thin filaments of striated muscles and the spectrin-based membrane…”
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Experimental and theoretical investigations of heat generation rates for a water cooled LiFePO4 battery by Panchal, S., Dincer, I., Agelin-Chaab, M., Fraser, R., Fowler, M.

“…•Presents experimental method for heat generation measurement in Li-ion battery.•Method is based on temperature and heat flux measurement.•Experimental data…”
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Intrathecal drug delivery in the era of nanomedicine by Fowler, M.J., Cotter, J.D., Knight, B.E., Sevick-Muraca, E.M., Sandberg, D.I., Sirianni, R.W.

“…Administration of substances directly into the cerebrospinal fluid (CSF) that surrounds the brain and spinal cord is one approach that can circumvent the…”
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Thermal and electrical performance evaluations of series connected Li-ion batteries in a pack with liquid cooling by Malik, M., Dincer, I., Rosen, Marc A., Mathew, M., Fowler, M.

“…•Li-ion battery pack testing at 1C, 2C, 3C, 4C and drive cycle with liquid cooling.•Three 20Ah LiFePO4 cells connected in series tested with coolant at…”
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Analysis of Large-Scale Mutagenesis Data To Assess the Impact of Single Amino Acid Substitutions by Gray, Vanessa E, Hause, Ronald J, Fowler, Douglas M

“…Mutagenesis is a widely used method for identifying protein positions that are important for function or ligand binding. Advances in high-throughput DNA…”
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Battery state of the charge estimation using Kalman filtering by Mastali, M., Vazquez-Arenas, J., Fraser, R., Fowler, M., Afshar, S., Stevens, M.

“…Battery management system (BMS) requires an accurate prediction the remaining energy level or state of charge (SOC) of the cell or battery pack. However, in…”
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MaveDB: an open-source platform to distribute and interpret data from multiplexed assays of variant effect by Esposito, Daniel, Weile, Jochen, Shendure, Jay, Starita, Lea M, Papenfuss, Anthony T, Roth, Frederick P, Fowler, Douglas M, Rubin, Alan F

“…Multiplex assays of variant effect (MAVEs), such as deep mutational scans and massively parallel reporter assays, test thousands of sequence variants in a…”
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Transient electrochemical heat transfer modeling and experimental validation of a large sized LiFePO4/graphite battery by Panchal, S., Dincer, I., Agelin-Chaab, M., Fraser, R., Fowler, M.

“…•Design of battery IR imaging set-up for LFP battery.•Design of LiFePO4-20Ah in NX and meshing in ANSYS.•Transient electrochemical heat transfer modeling and…”
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Measuring the activity of protein variants on a large scale using deep mutational scanning by Fowler, Douglas M, Stephany, Jason J, Fields, Stanley

“…In this protocol, the authors describe deep mutational scanning, an approach that involves selecting for protein function followed by high-throughput DNA…”
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Simulation of lithium ion battery replacement in a battery pack for application in electric vehicles by Mathew, M., Kong, Q.H., McGrory, J., Fowler, M.

“…The design and optimization of the battery pack in an electric vehicle (EV) is essential for continued integration of EVs into the global market…”
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A statistical framework for analyzing deep mutational scanning data by Rubin, Alan F, Gelman, Hannah, Lucas, Nathan, Bajjalieh, Sandra M, Papenfuss, Anthony T, Speed, Terence P, Fowler, Douglas M

“…Deep mutational scanning is a widely used method for multiplex measurement of functional consequences of protein variants. We developed a new deep mutational…”
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Thermal modeling and validation of temperature distributions in a prismatic lithium-ion battery at different discharge rates and varying boundary conditions by Panchal, S., Dincer, I., Agelin-Chaab, M., Fraser, R., Fowler, M.

“…•Designed and developed the battery thermal management system.•Studied average surface temperature distributions with varying boundary conditions.•Studied the…”
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Deep mutational scanning: assessing protein function on a massive scale by Araya, Carlos L, Fowler, Douglas M

“…Analysis of protein mutants is an effective means to understand their function. Protein display is an approach that allows large numbers of mutants of a…”
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Oxygen isotopes in titanite and apatite, and their potential for crustal evolution research by Bruand, E., Storey, C., Fowler, M., Heilimo, E.

“…Oxygen isotope analysis of zircon, often combined with geochronology and Hf isotope analysis, has been pivotal in understanding the evolution of continental…”
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Functional amyloid--from bacteria to humans by Fowler, Douglas M, Koulov, Atanas V, Balch, William E, Kelly, Jeffery W

“…Amyloid--a fibrillar, cross beta-sheet quaternary structure--was first discovered in the context of human disease and tissue damage, and was thought to always…”
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Regional MJO Modulation of Northwest Pacific Tropical Cyclones Driven by Multiple Transient Controls by Fowler, M. D., Pritchard, M. S.

“…The Madden–Julian Oscillation (MJO) is widely acknowledged for its ability to modulate Northwest Pacific tropical cyclones (TCs), but a complete understanding…”
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